Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Metyrapone
CAS:Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.Formula:C14H14N2OPurezza:99.03% - ≥95%Colore e forma:Crystals From Ether & Pentane SolidPeso molecolare:226.27Myricetin
CAS:Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.Formula:C15H10O8Purezza:97.92% - 99.85%Colore e forma:Yellow Needles From Dilute Alcohol SolidPeso molecolare:318.24Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Formula:C20H28O2Purezza:97.21% - 99.60%Colore e forma:Yellow-Orange PowderPeso molecolare:300.44Telmisartan
CAS:Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.Formula:C33H30N4O2Purezza:99.88% - 99.97%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:514.62Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormula:C25H35N7O9S4Purezza:99.63%Colore e forma:SolidPeso molecolare:705.85Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Formula:C20H18ClNO4Purezza:99.47% - 99.93%Colore e forma:Yellow Crystalline PowderPeso molecolare:371.80Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purezza:97.72% - 99.78%Colore e forma:SolidPeso molecolare:207.27Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Formula:C66H76Cl3N9O24Purezza:97.20% - 99.19%Colore e forma:Off White PowderPeso molecolare:1485.71Letrozole
CAS:<p>Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.</p>Formula:C17H11N5Purezza:98.67% - 99.84%Colore e forma:White To Off-Whitecrystalline PowderPeso molecolare:285.3Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Formula:C33H39ClN4O6Purezza:98% - 99.94%Colore e forma:Yellow Crystalline PowderPeso molecolare:623.14Ref: TM-T0486L
10mg35,00€25mg52,00€50mg69,00€100mg95,00€200mg136,00€500mg268,00€1mL*10mM (DMSO)74,00€ZX-29
CAS:ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Formula:C23H28ClN7O3SPurezza:98.32%Colore e forma:SolidPeso molecolare:518.03Ref: TM-T13416
1mg92,00€5mg230,00€10mg364,00€25mg620,00€50mg848,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)264,00€Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formula:C14H24Cl2N2O3Purezza:99.58%Colore e forma:Crystalline SolidPeso molecolare:339.258LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Formula:C23H26O3Purezza:98.65%Colore e forma:SolidPeso molecolare:350.45Ref: TM-T11844
2mg47,00€5mg70,00€10mg97,00€25mg167,00€50mg249,00€100mg369,00€200mg545,00€1mL*10mM (DMSO)77,00€Felodipine
CAS:Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.Formula:C18H19Cl2NO4Purezza:99.91%Colore e forma:SolidPeso molecolare:384.25Ref: TM-T0145
2mg35,00€5mg49,00€10mg71,00€25mg92,00€50mg130,00€100mg172,00€500mg432,00€1mL*10mM (DMSO)57,00€Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purezza:98.34% - 99.85%Colore e forma:Physical Description Beige Solid (Ntp 1992)Peso molecolare:205.64Isoliquiritigenin
CAS:Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.Formula:C15H12O4Purezza:97.61% - 99.44%Colore e forma:PowderPeso molecolare:256.25Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formula:C27H29NO11·HClPurezza:98% - 99.52%Colore e forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecolare:579.99Erlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4·HClPurezza:99.78% - 99.85%Colore e forma:White Or Off-White PowderPeso molecolare:429.9Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purezza:98.22% - 99.88%Colore e forma:Beige To Brown Fine Crystalline PowderPeso molecolare:250.09Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formula:C23H19F3N4O3Purezza:97.53%Colore e forma:SolidPeso molecolare:456.429-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purezza:99.32%Colore e forma:SolidPeso molecolare:404.35Ref: TM-T14066
1mg49,00€2mg70,00€5mg99,00€10mg163,00€25mg325,00€50mg472,00€100mg705,00€1mL*10mM (DMSO)116,00€Bicalutamide
CAS:<p>Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the</p>Formula:C18H14F4N2O4SPurezza:98% - 99.87%Colore e forma:Off-White Crystalline SolidPeso molecolare:430.37Pyrazinamide
CAS:Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFormula:C5H5N3OPurezza:99.71% - 99.9%Colore e forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecolare:123.11Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFormula:C27H29NO10·HClPurezza:96.21% - 99.53%Colore e forma:Cancer DrugPeso molecolare:563.99Ref: TM-T1511
5mg37,00€10mg56,00€25mg92,00€50mg119,00€100mg187,00€200mg298,00€500mg467,00€1mL*10mM (DMSO)63,00€Vitamin B3-d4
CAS:<p>Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.</p>Formula:C6HD4NO2Purezza:99.86%Colore e forma:SolidPeso molecolare:127.13Amiodarone hydrochloride
CAS:Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Formula:C25H29I2NO3·HClPurezza:99.82% - ≥95%Colore e forma:White To Cream Crystalline PowderPeso molecolare:681.78Itraconazole
CAS:Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Formula:C35H38Cl2N8O4Purezza:98% - 99.90%Colore e forma:Off-White Crystalline SolidPeso molecolare:705.63Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Formula:C9H16ClN3O2Purezza:98.36% - 99.44%Colore e forma:Solid SolidPeso molecolare:233.7Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormula:C7H8N4O2Purezza:99.65% - 99.98%Colore e forma:White Solid PowderPeso molecolare:180.16Acesulfame Potassium
CAS:Acesulfame potassium is a non-nutritive sweetener.Formula:C4H4KNO4SPurezza:99.65%Colore e forma:White Solid CrystallinePeso molecolare:201.24Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formula:CH4N2O2Purezza:99.85% - 99.92%Colore e forma:SolidPeso molecolare:76.05Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purezza:90.08% - 99.32%Colore e forma:Yellow PowderPeso molecolare:446.36Ref: TM-T2775
1g85,00€2gPrezzo su richiesta5gPrezzo su richiesta50mg37,00€100mg52,00€200mg51,00€500mg58,00€1mL*10mM (DMSO)52,00€Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurezza:99.05% - 99.75%Colore e forma:SolidPeso molecolare:494.00Tranexamic acid
CAS:Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.Formula:C8H15NO2Purezza:99.64% - 99.79%Colore e forma:White Crystalline PowderPeso molecolare:157.21Sulfacetamide sodium monohydrate
CAS:Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.Formula:C8H9N2NaO3S·H2OPurezza:99.92%Colore e forma:White Crystalline PowderPeso molecolare:254.2Colistin sulfate
CAS:Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Formula:C53H100N16O17SPurezza:98%Colore e forma:PowderPeso molecolare:1253.51Sulfanitran
CAS:Sulfanitran is a sulfonamide antibiotic used in the poultry industry.Formula:C14H13N3O5SPurezza:98.3% - 99.60%Colore e forma:SolidPeso molecolare:335.34Adapalene
CAS:Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.Formula:C28H28O3Purezza:99.53% - 99.76%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:412.52MLi-2
CAS:MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Formula:C21H25N5O2Purezza:98.96%Colore e forma:SolidPeso molecolare:379.46Ref: TM-T16115
1mg58,00€2mg88,00€5mg133,00€10mg188,00€25mg432,00€50mg652,00€100mg929,00€1mL*10mM (DMSO)142,00€Loperamide hydrochloride
CAS:Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Purezza:99.91% - >99.99%Colore e forma:Crystals Practically Insoluble In WaterPeso molecolare:513.50Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurezza:99.87%Colore e forma:White PowderPeso molecolare:416.57Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Formula:C15H24N2OPurezza:99.77% - >99.99%Colore e forma:SolidPeso molecolare:248.36Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formula:C27H44O7Purezza:99.06% - 99.67%Colore e forma:Canary Yellow Fine PowderPeso molecolare:480.63Paclitaxel
CAS:<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formula:C47H51NO14Purezza:98% - 99.92%Colore e forma:White PowderPeso molecolare:853.91Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formula:C24H40O4Purezza:99.70% - 99.93%Colore e forma:White - Almost White Solid PowderPeso molecolare:392.57Pemetrexed disodium
CAS:<p>Pemetrexed disodium treats lung cancer/mesothelioma; may cause moderate serum enzyme elevation, rarely acute liver injury.</p>Formula:C20H19N5Na2O6Purezza:99.29% - 99.49%Colore e forma:Crystalline SolidPeso molecolare:471.37Naproxen sodium
CAS:<p>Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.</p>Formula:C14H13NaO3Purezza:99.68% - 99.79%Colore e forma:White PowderPeso molecolare:252.24Vorinostat
CAS:Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.Formula:C14H20N2O3Purezza:99.47% - 99.65%Colore e forma:White Crystalline SolidPeso molecolare:264.32Sulfisoxazole
CAS:Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.Formula:C11H13N3O3SPurezza:99.87% - 99.98%Colore e forma:White To Cream PowderPeso molecolare:267.30Pentoxifylline
CAS:Pentoxifylline (PTX) stimulates cytokines, inhibits phosphodiesterase, enhances blood flow, and increases cell flexibility.Formula:C13H18N4O3Purezza:99.26% - 99.93%Colore e forma:SolidPeso molecolare:278.31
