Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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IKK 16 hydrochloride
CAS:IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.Formula:C28H30ClN5OSColore e forma:SolidPeso molecolare:520.09Pazopanib-d6
CAS:Pazopanib-d6 is a deuterated compound of Pazopanib.Formula:C21H17D6N7O2SPeso molecolare:443.56Venetoclax-d8
CAS:Venetoclax-d8 (ABT-199-d8) is a deuterated form of Venetoclax, a potent, selective, and orally active Bcl-2 inhibitor that induces autophagy and apoptosis.Formula:C45H42D8ClN7O7SColore e forma:SolidPeso molecolare:876.49Peptide R TFA
<p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>Formula:C39H57N13O8S2·xC2HF3O2Colore e forma:SolidPeso molecolare:900.08 (free base)Brivanib
CAS:Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormula:C19H19FN4O3Purezza:98.87%Colore e forma:SolidPeso molecolare:370.38Ref: TM-T6036
1mg47,00€5mg88,00€10mg144,00€25mg259,00€50mg375,00€100mg560,00€200mg815,00€1mL*10mM (DMSO)97,00€Cediranib maleate
CAS:Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Formula:C29H31FN4O7Colore e forma:SolidPeso molecolare:566.58Ref: TM-T2500L
5mg216,00€10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)236,00€Resveratrol analog 1
CAS:Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.Formula:C14H11FO2Purezza:98.42%Colore e forma:SolidPeso molecolare:230.23Rupatadine
CAS:Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.Formula:C26H26ClN3Purezza:99.87%Colore e forma:SolidPeso molecolare:415.96Silibinin-d3
Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.Formula:C25H22O10Colore e forma:SolidPeso molecolare:485.46Megestrol Acetate-d3
CAS:Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.Formula:C24H29D3O4Colore e forma:SolidPeso molecolare:387.53Afatinib D6
CAS:Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.Formula:C24H25ClFN5O3Colore e forma:SolidPeso molecolare:491.98Dexamethasone-d5
CAS:<p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>Formula:C22H24D5FO5Colore e forma:SolidPeso molecolare:397.49Pyrazinamide-d3
CAS:Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.Formula:C5D3H2N3OColore e forma:SolidPeso molecolare:126.13V-9302 hydrochloride
CAS:V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.Formula:C34H39ClN2O4Purezza:97.31%Colore e forma:SolidPeso molecolare:575.14Thiacloprid
CAS:Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.Formula:C10H9ClN4SPurezza:98.66% - 99.95%Colore e forma:Yellowish Crystalline PowderPeso molecolare:252.72Isorhapontigenin
CAS:Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.Formula:C15H14O4Purezza:98.49% - 99.85%Colore e forma:Off White Crystals PowerPeso molecolare:258.27Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purezza:97.78% - 99%Colore e forma:Colourless To Pale Yellow Liquid ViscousPeso molecolare:144.21Ginkgolide K
CAS:Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.Formula:C20H22O9Purezza:99.44% - 99.72%Colore e forma:SolidPeso molecolare:406.38PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Formula:C23H20F3N5O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:455.43Ref: TM-T4323
2mg35,00€5mg52,00€10mg88,00€25mg163,00€50mg235,00€100mg419,00€200mg545,00€1mL*10mM (DMSO)58,00€Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purezza:99.04% - 99.3%Colore e forma:SolidPeso molecolare:785.01Ref: TM-T3916
1mg35,00€5mg69,00€10mg88,00€25mg144,00€50mg205,00€100mg303,00€500mg735,00€1mL*10mM (DMSO)97,00€
