Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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Clematichinenoside AR
CAS:Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Formula:C82H134O43Purezza:99.04% - 99.69%Colore e forma:SolidPeso molecolare:1807.92Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Formula:C31H43N3O8Purezza:98.24% - 99.83%Colore e forma:Dark Purple SolidPeso molecolare:585.69TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purezza:99.17% - 99.53%Colore e forma:White Solid PowderPeso molecolare:166.22Selenomethionine
CAS:DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.Formula:C5H11NO2SePurezza:98% - 99.95%Colore e forma:Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidPeso molecolare:196.11Dimethyl fumarate
CAS:Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H8O4Purezza:90.51% - >99.99%Colore e forma:White To Off-White Powder White Crystalline PowderPeso molecolare:144.13JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Formula:C25H27Cl2N3OColore e forma:SolidPeso molecolare:456.41Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purezza:99.51% - 99.63%Colore e forma:SolidPeso molecolare:1031.18GNE0877
CAS:GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Formula:C14H16F3N7Purezza:98.01% - 99.97%Colore e forma:SolidPeso molecolare:339.32Ref: TM-T6031
1mg47,00€2mg60,00€5mg119,00€10mg187,00€25mg376,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)96,00€Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFormula:C14H11ClN6O3Purezza:99.25% - 99.41%Colore e forma:SolidPeso molecolare:346.73Ref: TM-T4219
2mg42,00€5mg62,00€10mg93,00€25mg169,00€50mg227,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)70,00€STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Formula:C19H10N2O3Purezza:97.14% - 98.8%Colore e forma:SolidPeso molecolare:314.29Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purezza:96.83% - 99.93%Colore e forma:SolidPeso molecolare:384.47ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurezza:98.84% - 99.50%Colore e forma:SolidPeso molecolare:371.41UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formula:C16H13N3Purezza:98.31%Colore e forma:SolidPeso molecolare:247.29Ref: TM-T7679
1mg40,00€5mg81,00€10mg116,00€25mg226,00€50mg324,00€100mg452,00€200mg632,00€1mL*10mM (DMSO)100,00€CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formula:C22H18Cl2N8Purezza:97.94% - ≥95%Colore e forma:SolidPeso molecolare:465.34Ref: TM-T2310
2mg43,00€5mg64,00€10mg96,00€25mg160,00€50mg254,00€100mg404,00€200mg603,00€500mg938,00€1mL*10mM (DMSO)70,00€Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purezza:99.02% - 99.73%Colore e forma:White PowderPeso molecolare:329.39Bergapten
CAS:Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.Formula:C12H8O4Purezza:99.48% - ≥95%Colore e forma:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Peso molecolare:216.19Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurezza:99.54% - ≥95%Colore e forma:White SolidPeso molecolare:327.83IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formula:C22H15Br2N3O4Purezza:98.92% - ≥95%Colore e forma:SolidPeso molecolare:545.18Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formula:C15H12O4Purezza:99.61% - >99.99%Colore e forma:SolidPeso molecolare:256.25MW-150 dihydrochloride dihydrate
CAS:MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.Formula:C24H29Cl2N5O2Colore e forma:SolidPeso molecolare:490.43
