Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purezza:99.42% - 99.79%Colore e forma:SolidPeso molecolare:443.85UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formula:C16H13N3Purezza:98.31%Colore e forma:SolidPeso molecolare:247.29Ref: TM-T7679
1mg38,00€5mg77,00€10mg110,00€25mg215,00€50mg306,00€100mg429,00€200mg600,00€1mL*10mM (DMSO)95,00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purezza:98.63% - >99.99%Colore e forma:Yellow SolidPeso molecolare:267.28Ref: TM-T2623
5mg40,00€10mg52,00€25mg82,00€50mg106,00€100mg177,00€200mg264,00€500mg444,00€1mL*10mM (DMSO)58,00€Retro-2
CAS:Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.
Formula:C19H16N2OSPurezza:98.15%Colore e forma:SolidPeso molecolare:320.41SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurezza:98.84%Colore e forma:SolidPeso molecolare:469.56BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formula:C10H9NO2SPurezza:98% - 99.92%Colore e forma:SolidPeso molecolare:207.25Ref: TM-T1902
5mg48,00€10mg54,00€25mg90,00€50mg161,00€100mg251,00€200mg378,00€500mg627,00€1mL*10mM (DMSO)50,00€Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purezza:99.14% - 99.95%Colore e forma:SolidPeso molecolare:416.46Ref: TM-T6S1917
5mg67,00€10mg90,00€25mg190,00€50mg286,00€100mg429,00€500mg982,00€1mL*10mM (DMSO)74,00€Fasudil hydrochloride hydrate
CAS:Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.Formula:C28H38Cl2N6O5S2Colore e forma:SolidPeso molecolare:673.67Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4·HClPurezza:99.28% - 99.98%Colore e forma:White Crystalline Granular OdorlessPeso molecolare:299.66Brefeldin A
CAS:Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).Formula:C16H24O4Purezza:96.45% - 99.89%Colore e forma:White SolidPeso molecolare:280.36Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formula:C24H40O3Purezza:98% - 99.93%Colore e forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecolare:376.57Sanguinarine
CAS:Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.Formula:C20H14NO4Purezza:99.04% - 99.76%Colore e forma:SolidPeso molecolare:332.33Bicyclol
CAS:Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.
Formula:C19H18O9Purezza:99.64% - 99.85%Colore e forma:SolidPeso molecolare:390.34BL-918
CAS:BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.Formula:C23H15F8N3OSPurezza:99.4% - 99.89%Colore e forma:SolidPeso molecolare:533.44Ref: TM-T8322
1mg50,00€2mg66,00€5mg99,00€10mg147,00€25mg269,00€50mg432,00€100mg708,00€500mg1.423,00€1mL*10mM (DMSO)120,00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14ABT-737
CAS:ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.Formula:C42H45ClN6O5S2Purezza:98.15% - >99.99%Colore e forma:SolidPeso molecolare:813.43FIPI HCl
CAS:FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.Formula:C23H25ClFN5O2Colore e forma:SolidPeso molecolare:457.93Lapatinib tosylate
CAS:Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Formula:C36H34ClFN4O7S2Colore e forma:SolidPeso molecolare:753.26Idarubicin
CAS:Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.Formula:C26H27NO9Colore e forma:SolidPeso molecolare:497.49MRT68921 HCl
CAS:MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).
Formula:C25H34N6O·HClPurezza:99.86% - 99.98%Colore e forma:SolidPeso molecolare:471.04
