Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1492 prodotti di "Autofagia"
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TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purezza:99.17% - 99.53%Colore e forma:White Solid PowderPeso molecolare:166.22Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purezza:99.04% - 99.3%Colore e forma:SolidPeso molecolare:785.01Ref: TM-T3916
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€500mg695,00€1mL*10mM (DMSO)92,00€Thiacloprid
CAS:Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.Formula:C10H9ClN4SPurezza:98.66% - 99.95%Colore e forma:Yellowish Crystalline PowderPeso molecolare:252.72PFE-360
CAS:PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).
Formula:C16H16N6OPurezza:98.14% - 99.73%Colore e forma:SolidPeso molecolare:308.34Mocetinostat
CAS:Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formula:C23H20N6OPurezza:99% - 99.21%Colore e forma:SolidPeso molecolare:396.44Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Formula:C20H15Cl3N2OSPurezza:99.483%Colore e forma:SolidPeso molecolare:437.77Ref: TM-T50005
5mg55,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€1mL*10mM (DMSO)79,00€NAcM-OPT HCl(2089293-61-6 free base)
CAS:NAcM-OPT HCL: Oral DCN1 inhibitor targeting N-Acetyl-UBE2M & DCN1, IC50=79 nM.Formula:C23H30Cl3N3OPurezza:99.43%Colore e forma:SolidPeso molecolare:470.86Ref: TM-T9140
2mg35,00€5mg49,00€10mg87,00€25mg140,00€50mg226,00€100mg370,00€500mg879,00€1mL*10mM (DMSO)93,00€AZD-8055
CAS:AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.
Formula:C25H31N5O4Purezza:98% - 99.69%Colore e forma:SolidPeso molecolare:465.54ARRY-797
CAS:ARRY-797 (ARRY-371797) is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
Formula:C22H26F2N4O2Purezza:98.97% - 99.81%Colore e forma:SolidPeso molecolare:416.46Sulfosuccinimidyl oleate sodium
CAS:Sulfosuccinimidyl oleate sodium is a long-chain fatty acid that inhibits fatty acid transport into cells.Cost-effective and quality-assured.Formula:C22H36NNaO7SPurezza:96.53%Colore e forma:SolidPeso molecolare:481.58Ref: TM-T13036L
1mg35,00€5mg69,00€10mg111,00€25mg177,00€50mg284,00€100mg447,00€200mg575,00€500mg888,00€Lamotrigine hydrate
CAS:Lamotrigine hydrate: oral anticonvulsant, blocks Na+ channels, stabilizes neurons, inhibits glutamate, treats epilepsy, focal seizure.Formula:C9H9Cl2N5OColore e forma:SolidPeso molecolare:274.11Entrectinib
CAS:Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C31H34F2N6O2Purezza:98.03% - 99.61%Colore e forma:SolidPeso molecolare:560.64Ref: TM-T3678
2mg42,00€5mg59,00€10mg88,00€25mg111,00€50mg168,00€100mg283,00€500mg692,00€1mL*10mM (DMSO)69,00€Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formula:C15H10O7Purezza:96.29% - 98.05%Colore e forma:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Peso molecolare:302.24Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5SPurezza:98.85% - 99.99%Colore e forma:SolidPeso molecolare:556.76PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Formula:C23H20F3N5O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:455.43Ref: TM-T4323
2mg34,00€5mg50,00€10mg84,00€25mg155,00€50mg222,00€100mg396,00€200mg515,00€1mL*10mM (DMSO)55,00€MRT68921
CAS:MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.Formula:C25H34N6OPurezza:99.23%Colore e forma:SolidPeso molecolare:434.58KU-55933
CAS:KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.
Formula:C21H17NO3S2Purezza:97.21% - >99.99%Colore e forma:SolidPeso molecolare:395.49CGI-1746
CAS:CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Formula:C34H37N5O4Purezza:97.69% - 97.88%Colore e forma:SolidPeso molecolare:579.69Tolvaptan
CAS:Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.
Formula:C26H25ClN2O3Purezza:99.78% - >99.99%Colore e forma:SolidPeso molecolare:448.94Telaglenastat hydrochloride
CAS:Telaglenastat (CB-839) HCl: First-in-class, oral GLS1 inhibitor, targets KGA/GAC, IC50 23-28 nM, triggers autophagy, anticancer.Formula:C26H25ClF3N7O3SColore e forma:SolidPeso molecolare:608.04
