Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formula:C8H7NO2SPurezza:99.33% - 99.79%Colore e forma:SolidPeso molecolare:181.21Valinomycin
CAS:Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormula:C54H90N6O18Purezza:95.37% - 97.16%Colore e forma:White SolidPeso molecolare:1111.32Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purezza:98.53% - 99%Colore e forma:SolidPeso molecolare:344.32LYN-1604
CAS:LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
Formula:C33H43Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:584.62SR9009
CAS:SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.Formula:C20H24ClN3O4SPurezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:437.94Ref: TM-T3685
2mg39,00€5mg58,00€10mg93,00€25mg137,00€50mg236,00€100mg384,00€200mg568,00€1mL*10mM (DMSO)64,00€Kaempferol
CAS:Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.
Formula:C15H10O6Purezza:98% - 99.41%Colore e forma:Yellow Needles From Alcohol And Water SolidPeso molecolare:286.24DPN
CAS:DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formula:C15H13NO2Purezza:99.01%Colore e forma:Off-White SolidPeso molecolare:239.27Nutlin-3a
CAS:Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purezza:95.62% - 99.71%Colore e forma:SolidPeso molecolare:581.49Ref: TM-T6023
1mg50,00€2mg66,00€5mg90,00€10mg156,00€25mg254,00€50mg376,00€100mg557,00€1mL*10mM (DMSO)128,00€FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formula:C23H24FN5O2Purezza:97.21% - 98.68%Colore e forma:SolidPeso molecolare:421.47Quercitrin
CAS:Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.Formula:C21H20O11Purezza:98.89% - 99.66%Colore e forma:Yellow Crystals From Dil Methanol Or Ethanol SolidPeso molecolare:448.38Quisinostat dihydrochloride
CAS:Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。Formula:C21H28Cl2N6O2Purezza:97.13%Colore e forma:SolidPeso molecolare:467.39Ref: TM-T6865
1mg62,00€5mg120,00€10mg170,00€25mg294,00€50mg411,00€100mg573,00€200mg807,00€1mL*10mM (DMSO)123,00€3-Bromopyruvic acid
CAS:3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.
Formula:C3H3BrO3Purezza:95% - 99.644%Colore e forma:White To Pale Yellow Crystalline PowderPeso molecolare:166.96Fangchinoline
CAS:Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:608.72AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purezza:99.87% - 99.95%Colore e forma:SolidPeso molecolare:408.45Dioscin
CAS:Dioscin (Collettiside III) is a saponin with antitumor activities.Formula:C45H72O16Purezza:99.85% - 99.87%Colore e forma:SolidPeso molecolare:869.04Ref: TM-T6473
5mg34,00€10mg42,00€25mg58,00€50mg81,00€100mg105,00€200mg152,00€500mg245,00€1mL*10mM (DMSO)52,00€GLPG1837
CAS:GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.Formula:C16H20N4O3SPurezza:99.64% - 99.91%Colore e forma:SolidPeso molecolare:348.42Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurezza:97.88% - 99.75%Colore e forma:SolidPeso molecolare:436.26Turofexorate Isopropyl
CAS:Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
Formula:C25H24F2N2O3Purezza:98.55% - 99.73%Colore e forma:SolidPeso molecolare:438.47SGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Formula:C20H22F3N5OPurezza:99.3% - >99.99%Colore e forma:SolidPeso molecolare:405.42Milciclib
CAS:Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formula:C25H32N8OPurezza:99.28%Colore e forma:SolidPeso molecolare:460.57Ref: TM-T6081
1mg49,00€5mg101,00€10mg168,00€25mg356,00€50mg572,00€100mg858,00€200mg1.153,00€1mL*10mM (DMSO)104,00€
