Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormula:C21H23N3O5Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:397.42Ref: TM-T7130
1mg38,00€5mg80,00€10mg114,00€25mg200,00€50mg299,00€100mg442,00€500mg973,00€1mL*10mM (DMSO)88,00€PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formula:C20H13FN4O2Purezza:98.65%Colore e forma:SolidPeso molecolare:360.34AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purezza:99.39%Colore e forma:SolidPeso molecolare:896.07SB-265610
CAS:SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.Formula:C14H9BrN6OPurezza:99.5%Colore e forma:SolidPeso molecolare:357.16Ref: TM-T16850
1mg56,00€5mg119,00€10mg187,00€25mg376,00€50mg560,00€100mg800,00€500mg1.644,00€1mL*10mM (DMSO)131,00€ML339
CAS:ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
Formula:C26H32ClN3O5Purezza:99.9%Colore e forma:SolidPeso molecolare:502AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formula:C21H28ClN5Purezza:98.38% - 98.57%Colore e forma:SolidPeso molecolare:385.93CTCE 9908 acetate
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.Formula:C88H151N27O25Purezza:98.47%Colore e forma:SolidPeso molecolare:1987.31MSX-127
CAS:MSX-127 elicites positive response in peptide CXCR4.Formula:C16H24N2O4Purezza:98.43%Colore e forma:SolidPeso molecolare:308.37WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formula:C18H18N4Purezza:99.42% - ≥95%Colore e forma:SolidPeso molecolare:290.36USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurezza:98.46% - 99.56%Colore e forma:SolidPeso molecolare:422.57Ref: TM-T17208
1mg42,00€5mg88,00€10mg127,00€25mg250,00€50mg393,00€100mg628,00€500mg1.304,00€1mL*10mM (DMSO)87,00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purezza:99.21%Colore e forma:SolidPeso molecolare:531.13Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purezza:98% - 99.5%Colore e forma:SolidPeso molecolare:855.02JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Formula:C25H26ClN3OPurezza:98.7% - 99.44%Colore e forma:SolidPeso molecolare:419.95Ref: TM-T5849
1mg35,00€5mg78,00€10mg117,00€25mg198,00€50mg310,00€100mg460,00€200mg665,00€1mL*10mM (DMSO)87,00€TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.Formula:C92H144N34O21S2Purezza:98.33% - 99.71%Colore e forma:SolidPeso molecolare:2126.47MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Formula:C36H26N4Purezza:99.19%Colore e forma:SolidPeso molecolare:514.62SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purezza:99.65% - 99.92%Colore e forma:SolidPeso molecolare:475.53Plerixafor
CAS:Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.Formula:C28H54N8Purezza:99.17% - >99.99%Colore e forma:SolidPeso molecolare:502.78AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Formula:C18H22F2N4O5S2Purezza:98.38% - 98.63%Colore e forma:SolidPeso molecolare:476.52Ref: TM-T7681
1mg37,00€2mg49,00€5mg70,00€10mg103,00€25mg202,00€50mg311,00€100mg472,00€200mgPrezzo su richiesta1mL*10mM (DMSO)78,00€Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Formula:C28H62Cl8N8Purezza:98.01% - 99.79%Colore e forma:SolidPeso molecolare:794.46SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurezza:98.19% - 99.61%Colore e forma:SolidPeso molecolare:467.2
