Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Isobavachalcone
CAS:Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in
Formula:C20H20O4Purezza:98% - 99.76%Colore e forma:SolidPeso molecolare:324.37HG-10-102-01
CAS:HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Formula:C17H20ClN5O3Purezza:99.59%Colore e forma:SolidPeso molecolare:377.83Ref: TM-T7196
2mg35,00€5mg55,00€10mg89,00€25mg161,00€50mg250,00€100mg360,00€200mg512,00€1mL*10mM (DMSO)62,00€Lucanthone
CAS:Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formula:C20H24N2OSPurezza:99.92%Colore e forma:Yellow Crystals From Alcohol SolidPeso molecolare:340.48Ref: TM-T4569
1mg52,00€2mg75,00€5mg119,00€10mg178,00€25mg379,00€50mg560,00€100mg793,00€1mL*10mM (DMSO)133,00€Pennogenin 3-O-β-chacotrioside
CAS:Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.Formula:C45H72O17Purezza:99.69% - 99.77%Colore e forma:SolidPeso molecolare:885.04RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purezza:98.49% - 99.55%Colore e forma:SolidPeso molecolare:292.37Ref: TM-T1798
1mg35,00€5mg66,00€10mg96,00€25mg187,00€50mg279,00€100mg420,00€200mg607,00€1mL*10mM (DMSO)89,00€4EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formula:C18H12Cl2N4O4SPurezza:96.8% - 99.12%Colore e forma:SolidPeso molecolare:451.28Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purezza:97.79% - >99.99%Colore e forma:Yellow SolidPeso molecolare:384.24Ref: TM-T2399
5mg50,00€10mg60,00€25mg75,00€50mg92,00€100mg137,00€200mg213,00€500mg353,00€1mL*10mM (DMSO)50,00€CZC-25146 hydrochloride
CAS:CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.
Formula:C22H26ClFN6O4SPurezza:98.76%Colore e forma:SolidPeso molecolare:525Danshensu
CAS:Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.
Formula:C9H10O5Purezza:98.4% - 99.74%Colore e forma:SolidPeso molecolare:198.17SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purezza:99.47% - 99.92%Colore e forma:SolidPeso molecolare:402.91Ref: TM-T2170
5mg57,00€10mg86,00€25mg138,00€50mg243,00€100mg470,00€200mg717,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Vitexin
CAS:Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.Formula:C21H20O10Purezza:98.13% - 99.64%Colore e forma:Yellow PowderPeso molecolare:432.3810074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purezza:99.51% - 99.94%Colore e forma:SolidPeso molecolare:332.31Ref: TM-T3686
2mg39,00€5mg59,00€10mg84,00€25mg135,00€50mg213,00€100mg375,00€200mg535,00€500mg853,00€1mL*10mM (DMSO)65,00€KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formula:C26H29ClN2O4SPurezza:99.56% - 99.86%Colore e forma:White SolidPeso molecolare:501.04Ref: TM-T2697
1mg54,00€2mg74,00€5mg107,00€10mg146,00€25mg289,00€50mg358,00€100mg523,00€1mL*10mM (DMSO)120,00€Taxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purezza:94.91% - 98.9%Colore e forma:Yellowish PowderPeso molecolare:304.25RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurezza:99.56%Colore e forma:SolidPeso molecolare:518.41Ref: TM-T6296
1mg44,00€2mg59,00€5mg93,00€10mg140,00€25mg253,00€50mg413,00€100mg605,00€1mL*10mM (DMSO)94,00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purezza:99.99%Colore e forma:White Or Off-White PowderPeso molecolare:146.14IU1
CAS:IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂，可以穿透细胞，IC50为 4.7 μM。Formula:C18H21FN2OPurezza:98% - 99.3%Colore e forma:SolidPeso molecolare:300.37PF-3845
CAS:PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Formula:C24H23F3N4O2Purezza:99.54% - 99.58%Colore e forma:SolidPeso molecolare:456.46Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purezza:98.75% - 99.57%Colore e forma:SolidPeso molecolare:199.25Ref: TM-T4414
5mg73,00€10mg105,00€25mg207,00€50mg368,00€100mg652,00€500mg1.320,00€1mL*10mM (DMSO)81,00€ML-SA1
CAS:ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.Formula:C22H22N2O3Purezza:99.34% - 99.71%Colore e forma:SolidPeso molecolare:362.42Ref: TM-T23004
2mg34,00€5mg49,00€10mg77,00€25mg142,00€50mg230,00€100mg344,00€200mg520,00€1mL*10mM (DMSO)55,00€
