Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formula:C18H14N2O4Purezza:95.85% - 99.22%Colore e forma:SolidPeso molecolare:322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formula:C27H45IN2Purezza:98.60%Colore e forma:SolidPeso molecolare:524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€CX546
CAS:CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formula:C14H17NO3Purezza:99.75%Colore e forma:SolidPeso molecolare:247.295-Aminolevulinic acid hydrochloride
CAS:5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Formula:C5H10ClNO3Purezza:98% - 99.97%Colore e forma:White To Pale Yellow Crystals OrPeso molecolare:167.59Ulipristal acetate
CAS:Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Formula:C30H37NO4Purezza:98.83% - 99.94%Colore e forma:SolidPeso molecolare:475.62Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purezza:99.6% - 99.84%Colore e forma:SolidPeso molecolare:719.91Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purezza:98.67%Colore e forma:SolidPeso molecolare:487.93Ref: TM-T4S0797
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mg93,00€100mg125,00€500mg266,00€1mL*10mM (DMSO)55,00€Ginkgetin
CAS:Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Formula:C32H22O10Purezza:98.63% - 99.94%Colore e forma:SolidPeso molecolare:566.51Ref: TM-T4S2126
1mg46,00€5mg92,00€10mg146,00€25mg250,00€50mg369,00€100mg545,00€200mg777,00€1mL*10mM (DMSO)114,00€Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Formula:C10H19N2O5PPurezza:99.99% - ≥95%Colore e forma:SolidPeso molecolare:278.24Ref: TM-T6641
1mg34,00€5mg67,00€10mg93,00€25mg152,00€50mg230,00€100mg363,00€200mg528,00€1mL*10mM (DMSO)67,00€Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.
Formula:C4H11N5Purezza:99.77% - >99.99%Colore e forma:SolidPeso molecolare:129.16Indomethacin farnesil
CAS:Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.Formula:C34H40ClNO4Purezza:97.29%Colore e forma:SolidPeso molecolare:562.14SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurezza:98% - 99.84%Colore e forma:Pale YellowPeso molecolare:331.34CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Formula:C29H30ClN5O2SPurezza:99.69%Colore e forma:SolidPeso molecolare:548.1Ref: TM-T14860
1mg50,00€2mg71,00€5mg113,00€10mg166,00€25mg334,00€50mg520,00€100mg750,00€1mL*10mM (DMSO)137,00€Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purezza:96.68% - 98.229%Colore e forma:SolidPeso molecolare:320.25MHY1485
CAS:MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.Formula:C17H21N7O4Purezza:97.74% - >99.99%Colore e forma:SolidPeso molecolare:387.39(-)-Epicatechin gallate
CAS:(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.Formula:C22H18O10Purezza:99.16% - 99.93%Colore e forma:SolidPeso molecolare:442.371-Monomyristin
CAS:1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFormula:C17H34O4Purezza:99.58%Colore e forma:SolidPeso molecolare:302.45Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purezza:97.82% - 98.3%Colore e forma:SolidPeso molecolare:676.66CFTR(inh)-172
CAS:CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.Formula:C18H10F3NO3S2Purezza:98% - 99.72%Colore e forma:SolidPeso molecolare:409.4Ref: TM-T2355
1mg34,00€2mg43,00€5mg63,00€10mg92,00€25mg178,00€50mg340,00€100mg502,00€1mL*10mM (DMSO)65,00€
