Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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PF-06455943
CAS:PF-06455943: LRRK2 inhibitor, IC50=3nM, PET radioligand, used for ADME/neuro PK & Parkinson's research.Formula:C17H14FN5OColore e forma:SolidPeso molecolare:323.32Poloppin
CAS:Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.Formula:C20H15BrF3NO2Purezza:98%Colore e forma:SolidPeso molecolare:438.24AMD 3465
CAS:AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).Formula:C24H38N6Purezza:98%Colore e forma:SolidPeso molecolare:410.60Fluoxetine oxalate
CAS:Fluoxetine oxalate, an SSRI, treats depression, OCD, bulimia, panic, and PMS.Formula:C19H20F3NO5Colore e forma:SolidPeso molecolare:399.36Nicodicosapent
CAS:Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.Formula:C28H39N3O2Purezza:98%Colore e forma:SolidPeso molecolare:449.63GSK3-IN-3
CAS:<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Formula:C24H35N3O4Purezza:99.37%Colore e forma:SolidPeso molecolare:429.55Xantocillin
CAS:Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.Formula:C18H12N2O2Purezza:98%Colore e forma:SolidPeso molecolare:288.3Methophenazine diethanesulfonate
CAS:Methophenazine diethanesulfonate is a Calmodulin antagonist.Formula:C35H48ClN3O11S3Colore e forma:SolidPeso molecolare:818.41Olacaftor
CAS:Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).Formula:C29H34FN3O4SColore e forma:SolidPeso molecolare:539.66CXCR4 antagonist 5
CAS:CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.Formula:C21H30N6Colore e forma:SolidPeso molecolare:366.5CUR5g
CAS:CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formula:C22H20N2O2Purezza:98.92%Colore e forma:SolidPeso molecolare:344.41Ref: TM-T73550
1mg92,00€5mg216,00€10mg344,00€25mg692,00€50mg1.103,00€100mg1.644,00€1mL*10mM (DMSO)240,00€Ambroxol-d5
CAS:Ambroxol-d5 is a standard for quantifying ambroxol in GC/LC-MS, an expectorant metabolite of bromhexine improving mucociliary functions.Formula:C13H13Br2D5N2OPeso molecolare:383.13p38 MAPK-IN-2
CAS:p38 MAPK-IN-2 is an inhibitor of p38 kinase.Formula:C20H19ClFN5O2Purezza:98%Colore e forma:SolidPeso molecolare:415.85(3S,5R)-Rosuvastatin
CAS:(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).Formula:C22H28FN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:481.54Ivacaftor hydrate
CAS:Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.Formula:C24H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:410.514Dinoprost
CAS:Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formula:C20H34O5Purezza:97.94% - 98.04%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:354.48Ref: TM-T15133
5mg51,00€10mg79,00€25mg144,00€50mg216,00€100mg344,00€200mg512,00€1mL*10mM (DMSO)57,00€CP-53631
CAS:CP-53631 is a selective serotonin reuptake inhibitor (SSRI)Formula:C17H19BrClNColore e forma:SolidPeso molecolare:352.7GSK812397
CAS:GSK812397 inhibits X4-tropic HIV-1 with high potency, targeting CXCR4 receptor noncompetitively and showing broad efficacy and good pharmacokinetics.Formula:C24H32N6OColore e forma:SolidPeso molecolare:420.55SMER18
CAS:SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.Formula:C16H14ClNO2Purezza:97.27%Colore e forma:SolidPeso molecolare:287.74Ref: TM-T16900
1mg133,00€5mg329,00€10mg472,00€25mg914,00€50mg1.415,00€100mg1.882,00€1mL*10mM (DMSO)360,00€MF-095
CAS:MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.Formula:C27H31N3O4SColore e forma:SolidPeso molecolare:493.62
