CaSR
Il recettore sensibile al calcio (CaSR) è un GPCR che svolge un ruolo vitale nel mantenimento dell'omeostasi del calcio regolando la secrezione dell'ormone paratiroideo e il riassorbimento del calcio nei reni. Il CaSR è anche coinvolto in vari altri processi fisiologici, tra cui il metabolismo osseo e la funzione vascolare. I modulatori del CaSR sono utilizzati nel trattamento di condizioni come l'iperparatiroidismo, l'osteoporosi e le malattie cardiovascolari. Presso CymitQuimica, offriamo una selezione di modulatori del CaSR di alta qualità per supportare la tua ricerca nel metabolismo del calcio, endocrinologia e salute delle ossa.
Trovati 31 prodotti per "CaSR".
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AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.Formula:C17H17NOSPurezza:>99.99%Colore e forma:SolidPeso molecolare:283.39Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Formula:C12H6N2O8S·2SrPurezza:98.97%Colore e forma:White SolidPeso molecolare:513.49Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Formula:C24H26N2O2Purezza:98.88% - 99.68%Colore e forma:SolidPeso molecolare:374.48Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Formula:C11H15Cl2N3O6SPurezza:98.56%Colore e forma:Yellow SolidPeso molecolare:388.22Etelcalcetide
CAS:Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.Formula:C38H73N21O10S2Purezza:98%Colore e forma:SolidPeso molecolare:1048.26γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Formula:C11H17F3N2O7Colore e forma:SolidPeso molecolare:346.26Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Formula:C23H24N2O2Colore e forma:SolidPeso molecolare:360.45Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Formula:C22H22F3NPurezza:99.48%Colore e forma:Transparent LiquidPeso molecolare:357.41NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Formula:C24H25ClN2O2·HClPurezza:99.38% - 99.67%Colore e forma:White SolidPeso molecolare:445.38Ref: TM-T4967
1mg43,00€2mg56,00€5mg87,00€1mL*10mM (DMSO)95,00€10mg119,00€25mg203,00€50mg320,00€100mg475,00€TNCA
CAS:TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.Formula:C12H12N2O2Purezza:97.33% - 97.73%Colore e forma:SolidPeso molecolare:216.24Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFormula:Cl3GdPurezza:98%Colore e forma:SolidPeso molecolare:263.61Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Formula:C22H23ClF3NPurezza:99.96% - >99.99%Colore e forma:SolidPeso molecolare:393.87Ref: TM-T2406
1mL*10mM (DMSO)34,00€10mg48,00€25mg66,00€50mg84,00€100mg137,00€200mg175,00€500mg294,00€Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Formula:C38H73N21O10S2·xHClPurezza:>99.99%Colore e forma:White SolidPeso molecolare:1353.33NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Formula:C19H21N3OPurezza:97.13%Colore e forma:SolidPeso molecolare:307.389Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFormula:C18H22ClNOColore e forma:SolidPeso molecolare:303.83SB-423562 HCl
CAS:SB-423562 is a calcium-sensing receptor antagonist.Formula:C26H33ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:473Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Formula:C33H40O18Purezza:98% - 99.92%Colore e forma:SolidPeso molecolare:724.66Poly-D-lysine hydrobromide (MW 30000-70000)
CAS:Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is a peptide CaSR agonist that removes proteinase K-resistant PrP from SN56 neuroblastoma cells.Formula:(C6H14N2O2)x·xHBrColore e forma:Yellow ViscousPeso molecolare:227.102NPS-2143
CAS:NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.Formula:C24H25ClN2O2Purezza:99.56%Colore e forma:SolidPeso molecolare:408.92Calhex 231 hydrochloride
CAS:Calhex 231 hydrochloride a potent CaSR negative-conversion modulator that blocks the increase in [3H]inositol phosphate, inhibits mir-208a-mediated .Formula:C25H28Cl2N2OPurezza:99.36%Colore e forma:SolidPeso molecolare:443.41Ref: TM-T10666
25mgPrezzo su richiesta50mgPrezzo su richiesta1mg47,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg152,00€
