Recettore degli oppioidi
I recettori degli oppioidi sono un gruppo di recettori accoppiati alle proteine G che mediano gli effetti degli oppioidi endogeni ed esogeni. Questi recettori svolgono un ruolo centrale nella modulazione del dolore, nella regolazione dell'umore e nei comportamenti di dipendenza. Gli agonisti e antagonisti dei recettori degli oppioidi sono ampiamente utilizzati nella gestione del dolore e nel trattamento delle dipendenze, nonché nella ricerca sui disturbi neurologici e psichiatrici. Presso CymitQuimica, offriamo una selezione completa di modulatori dei recettori degli oppioidi di alta qualità per supportare la tua ricerca in neurobiologia, gestione del dolore e terapia delle dipendenze.
Trovati 328 prodotti per "Recettore degli oppioidi".
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Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formula:C19H24ClNO4Purezza:99.43%Colore e forma:SolidPeso molecolare:365.85BTRX-335140
CAS:BTRX-335140 (CYM-53093) is a potent and selective orally active κ-opioid receptor (KOR) antagonist with antagonistic activity.Cost-effective and quality-assured.Formula:C25H32FN5O2Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:453.55Ref: TM-T14835
1mg100,00€2mg146,00€5mg236,00€1mL*10mM (DMSO)268,00€10mg385,00€25mg797,00€50mg1.305,00€100mg1.783,00€200mg2.493,00€Meptazinol hydrochloride
CAS:Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.Formula:C15H23NO·HClPurezza:99.75%Colore e forma:White SolidPeso molecolare:269.81Trimebutine maleate
CAS:Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects.Formula:C26H33NO9Purezza:99.89% - 99.98%Colore e forma:White SolidPeso molecolare:503.55LY2940094
CAS:LY2940094 (LY-2940094) decreases ethanol self-administration in animal models.Formula:C22H23ClF2N4O2SPurezza:99.4%Colore e forma:SolidPeso molecolare:480.96Ref: TM-T15799
1mg77,00€2mg101,00€5mg155,00€1mL*10mM (DMSO)170,00€10mg259,00€25mg513,00€50mg737,00€100mg1.018,00€Apitegromab
CAS:Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases includingPurezza:97.59% (SDS-PAGE); 99.78% (SEC-HPLC) - >95.0% (SDS-PAGE); 99.62% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.06 kDaMatrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Formula:C15H24N2OPurezza:99.77% - >99.99%Colore e forma:SolidPeso molecolare:248.36CP 866087
CAS:CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.Formula:C24H30N2O3SPurezza:99.22% - 99.74%Colore e forma:SolidPeso molecolare:426.57Moguisteine
CAS:Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.Formula:C16H21NO5SPurezza:99.98%Colore e forma:SolidPeso molecolare:339.41Samidorphan HCl
CAS:Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors.Formula:C21H27ClN2O4Purezza:96.79% - 97.85%Colore e forma:SolidPeso molecolare:406.9ZT 52656A hydrochloride
CAS:ZT 52656A is a selective agonist of kappa opioid, and used for the prevention or alleviation of pain in the eye.Formula:C19H26ClF3N2OPurezza:98.78%Colore e forma:SolidPeso molecolare:390.87Ref: TM-T13414
1mg94,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg715,00€50mg1.144,00€100mg1.783,00€Alvimopan
CAS:Alvimopan is a potent opioid antagonist targeting gut receptors to reverse opioid effects on motility.Formula:C25H32N2O4Purezza:99.47% - 99.78%Colore e forma:SolidPeso molecolare:424.53Ref: TM-T1242
1mg44,00€2mg57,00€5mg93,00€1mL*10mM (DMSO)94,00€10mg120,00€25mg220,00€50mg356,00€100mg530,00€200mg755,00€Loperamide hydrochloride
CAS:Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Purezza:99.91% - >99.99%Colore e forma:Crystals Practically Insoluble In WaterPeso molecolare:513.50Naltrexone hydrochloride
CAS:Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.Formula:C20H24ClNO4Purezza:98.72% - 99.65%Colore e forma:White Crystalline PowderPeso molecolare:377.862CTOP
CAS:Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.Formula:C50H67N11O11S2Purezza:98%Colore e forma:SolidPeso molecolare:1062.28β-Naltrexamine dihydrochloride
CAS:β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.Formula:C20H28Cl2N2O3Purezza:95.98%Colore e forma:SolidPeso molecolare:415.35MT-7716 free base
CAS:MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.Formula:C27H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:440.54HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Formula:C23H24N8O5Colore e forma:SolidPeso molecolare:492.49Akuammicine
CAS:Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.Formula:C20H22N2O2Colore e forma:SolidPeso molecolare:322.408Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Formula:C26H31N3OPurezza:98%Colore e forma:SolidPeso molecolare:401.54BAM-22P
CAS:Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.Formula:C130H184N38O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2839.22Nociceptin(1-7)
CAS:Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesiaFormula:C31H41N7O9Purezza:98%Colore e forma:SolidPeso molecolare:655.709Dermorphin
CAS:Dermorphin is agonist of μ-opioid receptor (MOR) agonist.Formula:C40H50N8O10Purezza:98.82%Colore e forma:SolidPeso molecolare:802.87μ/κ/δ opioid receptor agonist 1
μ/κ/δopioid receptor agonist1 is an agonist for the μ opioid receptor (MOR), κ opioid receptor (KOR), and δ opioid receptor (DOR). It produces potent and long-lasting analgesic effects in the tail flick test through peripheral MOR and KOR activation.Formula:C35H45FN8O8Colore e forma:SolidPeso molecolare:724.33444DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Formula:C28H36F3N5O8Purezza:98%Colore e forma:SolidPeso molecolare:627.61[Des-Tyr1]-γ-Endorphin
CAS:[Des-Tyr1]-gamma-Endorphin is a neuropeptide found in human cerebrospinal fluid. It exhibits antidepressant activity, helps eliminate active avoidance behaviors in rats, and reduces passive avoidance behaviors in these animals.Formula:C74H122N18O25SColore e forma:SolidPeso molecolare:1695.93[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Formula:C65H107N21O15Purezza:99.59%Colore e forma:SolidPeso molecolare:1422.7[(pF)Phe4]Nociceptin(1-13)NH2
CAS:Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.Formula:C61H99FN22O15Purezza:98%Colore e forma:SolidPeso molecolare:1399.6Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Colore e forma:Odour SolidHerkinorin
CAS:Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.Formula:C28H30O8Colore e forma:SolidPeso molecolare:494.53Dermorphin Analog
Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.Formula:C44H59N11O10Purezza:98%Colore e forma:SolidPeso molecolare:901.43Dynorphin B (1-13)
CAS:Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formula:C74H115N21O17Purezza:98%Colore e forma:SolidPeso molecolare:1570.84Neuropeptide AF (human)
CAS:Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Formula:C90H132N26O25Purezza:98%Colore e forma:SolidPeso molecolare:1978.17KOR agonist 6
KOR agonist 6 is a KOR agonist with a Ki value of 0.25 pM. In CHO cells, it exhibits agonistic activity on MOR and DOR and inhibits forskolin-stimulated cAMP accumulation. The compound stimulates KOR-mediated [35S]GTPγS binding in HEK293 cells expressing KOR and effectively suppresses cAMP accumulation as a potent agonist, showing lower β-arrestin recruitment efficacy. Additionally, KOR agonist 6 demonstrates analgesic effects in mice and can be employed in the study of analgesics with reduced central nervous system (CNS) side effects.Colore e forma:Odour SolidU-54494A hydrochloride
CAS:U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Formula:C18H25Cl3N2OColore e forma:SolidPeso molecolare:391.76SNC 80
CAS:SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.Formula:C28H39N3O2Purezza:99.65%Colore e forma:SolidPeso molecolare:449.63Frakefamide TFA
Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.Formula:C32H35F4N5O7Colore e forma:SolidPeso molecolare:677.64[Nphe1]Nociceptin(1-13)NH2
CAS:Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.Formula:C61H100N22O15Purezza:98%Colore e forma:SolidPeso molecolare:1381.6DPDPE
CAS:DPDPE is selective δ-opioid receptor agonist peptide.Formula:C30H39N5O7S2Purezza:98%Colore e forma:SolidPeso molecolare:645.79KOR agonist 4
KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.Formula:C21H25N3Colore e forma:SolidPeso molecolare:319.44NP-5497-KA
NP-5497-KA is a κ-opioid receptor agonist with oral bioavailability.Formula:C26H39Cl3N4O2Peso molecolare:544.21386ICI 174,864
CAS:Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.Formula:C38H53N5O7Purezza:98%Colore e forma:White SolidPeso molecolare:691.87δ opioid receptor antagonist 1
Compound 6-Cy3, a δ-opioid receptor antagonist, serves as a highly selective fluorescent probe for δ-opioid receptors (DOR), showcasing an affinity (Ki=1.7 nM). This compound is used in the study of pain perception mechanisms.Colore e forma:Odour SolidAxelopran
CAS:Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.Formula:C26H39N3O4Colore e forma:SolidPeso molecolare:457.61KOR agonist 5
KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).Formula:C38H38N2O5Colore e forma:SolidPeso molecolare:602.72UFP-101
CAS:Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.
Formula:C82H138N32O21Purezza:98%Colore e forma:SolidPeso molecolare:1908.19Biphalin TFA
CAS:Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.Formula:C46H56N10O10·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:909.00 (free base)Ac-RYYRIK-NH2
CAS:NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Formula:C44H70N14O9Purezza:98%Colore e forma:SolidPeso molecolare:939.12Gluten Exorphin B5
CAS:Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.Formula:C30H38N6O7Purezza:98%Colore e forma:SolidPeso molecolare:594.66β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Formula:C156H249F3N42O46SColore e forma:SolidPeso molecolare:3537.96
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