Recettore degli oppioidi
I recettori degli oppioidi sono un gruppo di recettori accoppiati alle proteine G che mediano gli effetti degli oppioidi endogeni ed esogeni. Questi recettori svolgono un ruolo centrale nella modulazione del dolore, nella regolazione dell'umore e nei comportamenti di dipendenza. Gli agonisti e antagonisti dei recettori degli oppioidi sono ampiamente utilizzati nella gestione del dolore e nel trattamento delle dipendenze, nonché nella ricerca sui disturbi neurologici e psichiatrici. Presso CymitQuimica, offriamo una selezione completa di modulatori dei recettori degli oppioidi di alta qualità per supportare la tua ricerca in neurobiologia, gestione del dolore e terapia delle dipendenze.
Trovati 326 prodotti di "Recettore degli oppioidi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PIPE-3297
PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.Formula:C23H30N2OPeso molecolare:350.23581Naldemedine
CAS:Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.Formula:C32H34N4O6Colore e forma:SolidPeso molecolare:570.64Orphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Formula:C49H75N15O14Purezza:98%Colore e forma:SolidPeso molecolare:1098.2SB 205607 dihydrobromide
CAS:non-peptide δ1 opioid receptor agonistFormula:C23H24N2OPurezza:98%Colore e forma:SolidPeso molecolare:344.45HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Formula:C23H24N8O5Colore e forma:SolidPeso molecolare:492.49CSD-CH2(1,8)-NH2
CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM.Formula:C76H125N25O15S2Purezza:98%Colore e forma:SolidPeso molecolare:1693.09KOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formula:C21H25N3Colore e forma:SolidPeso molecolare:319.44[Arg14,Lys15]Nociceptin
CAS:Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Formula:C82H137N31O22Purezza:98%Colore e forma:SolidPeso molecolare:1909.18β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Formula:C156H249F3N42O46SColore e forma:SolidPeso molecolare:3537.96Dynorphin B (1-13) (TFA)
Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .Formula:C76H116N21F3O19Colore e forma:SolidPeso molecolare:1684.86Axelopran sulfate
CAS:Axelopran sulfate is used in Oral Therapies for Opioid-induced Bowel Dysfunction in Patients with Chronic Noncancer Pain.Formula:C26H41N3O8SColore e forma:SolidPeso molecolare:555.68β-Endorphin, equine
CAS:Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.Formula:C154H248N42O44SPurezza:98%Colore e forma:SolidPeso molecolare:3423.94Nociceptin(1-7)
CAS:Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesiaFormula:C31H41N7O9Purezza:98%Colore e forma:SolidPeso molecolare:655.709MT-7716 hydrochloride
CAS:MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)Formula:C27H29ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:477(S,S)-J-113397
CAS:(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .Formula:C24H37N3O2Colore e forma:SolidPeso molecolare:399.57[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Formula:C61H99FN22O15Purezza:98%Colore e forma:SolidPeso molecolare:1399.6β-Endorphin (6-31), human
CAS:β-Endorphin is an endogenous opioid neuropeptide and opioid receptor agonist that preferentially binds to μ-opioid receptors.Formula:C131H218N34O40Purezza:98%Colore e forma:SolidPeso molecolare:2909.38Clocinnamox mesylate
CAS:Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).Formula:C30H33ClN2O7SColore e forma:SolidPeso molecolare:601.11LY255582
CAS:LY255582 is a selective centrally active opioid receptor antagonist with high affinity for mu, delta and kappa receptors with Ki of 0.4 nM, 5.2, 2.0 nM,Formula:C22H35NO2Purezza:98%Colore e forma:SolidPeso molecolare:345.52R-6890
CAS:R-6890 is an opioid compound with analgesic properties.Formula:C21H24ClN3OColore e forma:SolidPeso molecolare:369.89
![[Arg14,Lys15]Nociceptin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1986.webp&w=3840&q=75)
![[(pF)Phe4]Nociceptin(1-13)NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1885.webp&w=3840&q=75)
