Recettore degli oppioidi
I recettori degli oppioidi sono un gruppo di recettori accoppiati alle proteine G che mediano gli effetti degli oppioidi endogeni ed esogeni. Questi recettori svolgono un ruolo centrale nella modulazione del dolore, nella regolazione dell'umore e nei comportamenti di dipendenza. Gli agonisti e antagonisti dei recettori degli oppioidi sono ampiamente utilizzati nella gestione del dolore e nel trattamento delle dipendenze, nonché nella ricerca sui disturbi neurologici e psichiatrici. Presso CymitQuimica, offriamo una selezione completa di modulatori dei recettori degli oppioidi di alta qualità per supportare la tua ricerca in neurobiologia, gestione del dolore e terapia delle dipendenze.
Trovati 326 prodotti di "Recettore degli oppioidi"
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[Met5]-Enkephalin, amide
CAS:[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Formula:C27H36N6O6SPurezza:98%Colore e forma:SolidPeso molecolare:572.68PL-017
CAS:μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.Formula:C29H37N5O5Purezza:98%Colore e forma:SolidPeso molecolare:535.64CTOP acetate
CTOP acetate is a somatostatin analogue and a μ-opioid receptor antagonist.Formula:C52H71N11O13S2Purezza:99.87%Colore e forma:SoildPeso molecolare:1122.32AH 7563
CAS:AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Formula:C16H24N2OColore e forma:SolidPeso molecolare:260.38Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Formula:C26H31N3OPurezza:98%Colore e forma:SolidPeso molecolare:401.54Orphine
CAS:Orphine is an opioid compound that can amplify the antinociceptive effects reduced by naloxone in mice.Formula:C20H23N3OColore e forma:SolidPeso molecolare:321.42Orphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Formula:C49H75N15O14Purezza:98%Colore e forma:SolidPeso molecolare:1098.2Opioid receptor agonist 1
<p>Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.</p>Formula:C32H45N5OColore e forma:SolidPeso molecolare:515.73SNC 80
CAS:SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.Formula:C28H39N3O2Purezza:99.65%Colore e forma:SolidPeso molecolare:449.63Dynorphin B (1-13) (TFA)
Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .Formula:C76H116N21F3O19Colore e forma:SolidPeso molecolare:1684.86Ac-RYYRWK-NH2 TFA
CAS:Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.Formula:C51H70F3N15O11Colore e forma:SolidPeso molecolare:1126.21(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS:E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioidFormula:C50H81N15O9Colore e forma:SolidPeso molecolare:1036.27[Nphe1]Nociceptin(1-13)NH2 TFA
[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.Formula:C63H101F3N22O17Colore e forma:SolidPeso molecolare:1495.61Dynorphin A (1-13) amide
CAS:Dynorphin A (1-13) amide, an endogenous opioid peptide, counteracts the analgesic effects of morphine [1].Formula:C75H127N25O14Peso molecolare:1602.97Alvimopan dihydrate (LY246736 dihydrate)
CAS:Alvimopan dihydrate is a potent, oral μ-opioid receptor blocker (IC50 1.7 nM, Ki 0.47 nM) used in postoperative ileus research.Formula:C25H36N2O6Colore e forma:SolidPeso molecolare:460.56Asimadoline
CAS:Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany.Formula:C27H30N2O2Colore e forma:SolidPeso molecolare:414.54Porcine dynorphin A(1-13)
CAS:Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.Formula:C75H126N24O15Purezza:98%Colore e forma:SolidPeso molecolare:1603.95Loperamide phenyl
CAS:Loperamide phenyl, an impurity detected in Loperamide, is an opioid receptor agonist.Formula:C35H37ClN2O2Colore e forma:SolidPeso molecolare:553.14BMS-986121
CAS:BMS-986121 is a selective positive allosteric modulator (PAM) of the μ opioid receptor with analgesic effects.Formula:C15H9Cl2N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:366.22Endomorphin 2 TFA
CAS:Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.Formula:C34H38F3N5O7Colore e forma:SolidPeso molecolare:685.69
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