Recettore dell'adenosina
I recettori dell'adenosina sono una classe di GPCR che rispondono al nucleoside endogeno adenosina. Questi recettori sono coinvolti nella regolazione di vari processi fisiologici, tra cui la funzione cardiovascolare, i cicli sonno-veglia e le risposte immunitarie. I modulatori dei recettori dell'adenosina hanno un potenziale terapeutico nel trattamento di condizioni come le aritmie cardiache, l'infiammazione e le malattie neurodegenerative. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori dell'adenosina di alta qualità per supportare la tua ricerca in biologia cardiovascolare, neuroscienze e immunologia.
Trovati 218 prodotti per "Recettore dell'adenosina".
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LUF6096
CAS:LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically whileFormula:C22H21Cl2N3OPurezza:99.5%Colore e forma:White SolidPeso molecolare:414.33A3AR agonist 1
A3AR Agonist 1 (Compound 12), with a Ki of 25.8 nM, is a potent A3 adenosine receptor (A3AR) agonist that promotes β-arrestin2 recruitment with an effectiveFormula:C28H34N6O6Purezza:98%Colore e forma:SolidPeso molecolare:550.61Adenosine receptor agonist 1
Compound 6m, an A3 adenosine receptor (AR) partial agonist, exhibits a K i value of 6.7 nM as an adenosine receptor agonist.Formula:C12H14ClN5O2SeColore e forma:SolidPeso molecolare:374.68hA3AR agonist 2
hA3AR agonist 2 is a potent activator of A3AR, with a Ki value of 3.5 nM.Formula:C11H14ClN5O2SColore e forma:SolidPeso molecolare:315.78A3AR agonist 2
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM.Formula:C34H34N6O6Purezza:98%Colore e forma:SolidPeso molecolare:622.67Heterobivalent ligand-1
Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.Formula:C86H115FN16O21Colore e forma:SolidPeso molecolare:1727.93MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Formula:C27H29N5O5Purezza:99.00%Colore e forma:SolidPeso molecolare:503.55Xanthine amine congener dihydrochloride
CAS:XAC dihydrochloride is an Adenosine A1 and A2 receptor antagonist with IC50s of 1.8 nM and 114 nM, also a mouse convulsant.Formula:C21H30Cl2N6O4Colore e forma:SolidPeso molecolare:501.41LUF7690
CAS:LUF7690 (Compound 9), a clickable and covalent affinity-based probe (AfBP) for the human A3 adenosine receptor (hA3AR), facilitates the detection andFormula:C25H24FN5O6SColore e forma:SolidPeso molecolare:541.55A2A/A3 AR antagonist-1
A2A/A3 AR antagonist-1 is a dual fluorescent AR ligand with K i of 90 nM (hA2A) & 31.8 nM (hA3).Formula:C56H71N15O12S2Colore e forma:SolidPeso molecolare:1210.39A-286501
CAS:A-286501: Oral adenosine kinase inhibitor, IC50=0.47 nM, reduces pain via non-opioid, non-NSAID ADO receptors.Formula:C11H14BrN5O2Purezza:98%Colore e forma:SolidPeso molecolare:328.17Theophyllol
CAS:Theophyllol (theophylline sodium acetate) can alter calcium levels in subcellular fractions of rat brain cortex.Formula:C9H10N4Na2O4Colore e forma:SolidPeso molecolare:284.18Inupadenant
CAS:Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1].Formula:C25H26F2N8O4S2Colore e forma:SolidPeso molecolare:604.65ABT-702
CAS:ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.Formula:C22H19BrN6OPurezza:99.57%Colore e forma:SoildPeso molecolare:463.33AR ligand 40
AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonistic activity. It exhibits antiproliferative effects on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells, with EC50 values of 7, 10, 12, 13, 15, and 39 μM, respectively.Formula:C21H25N5Colore e forma:SolidPeso molecolare:347.211MIPS3526
MIPS3526 is a potent and selective A2B adenosine receptor (A2BR) agonist, exhibiting a pEC50 value of 10.17 (with an EC50 of 58 pM). It demonstrates high receptor subtype selectivity against A1R, A2AR, and A3R. MIPS3526 mitigates the stimulatory effects of angiotensin II on cardiomyocytes and fibroblasts and is useful in studying cardiovascular diseases, particularly heart failure driven by cardiac remodeling.A3AR modulator 1
MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.Formula:C23H25IN4Colore e forma:SolidPeso molecolare:484.38Adenosine receptor antagonist 1
CAS:A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.Formula:C22H15ClFN7OColore e forma:SolidPeso molecolare:447.863F6-9G5
3F6-9G5 is a humanized monoclonal antibody targeting AA2AR/Adenosine A2aR, used in neurodegenerative disease research.Purezza:>95%Colore e forma:LiquidPeso molecolare:146.66 kDaPSB 0777 ammonium hydrate
PSB 0777 ammonium hydrate is a potent and selective adenosine A2A receptor full agonist, exhibiting K i values of 44.4 nM for rat A2A receptors and 360 nM forFormula:C18H20N5O7S2·NH4·75H2OPurezza:98%Colore e forma:SolidPeso molecolare:532.09
