Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 505 prodotti per "Proteasi HIV".
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HIV-1 inhibitor-74
HIV-1inhibitor-74 (compound 10c) is a potent inhibitor of HIV-1, displaying an EC50 of 0.0047 µM against HIV-1IIIB. It exhibits cytotoxic properties and effectively inhibits the activity of WTHIV-1RT with an IC50 of 0.134 µM. Additionally, HIV-1inhibitor-74 demonstrates broad-spectrum anti-HIV-1 activity.Formula:C28H31N9O2SColore e forma:SolidPeso molecolare:557.67GLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formula:C102H194N40O20Purezza:98%Colore e forma:SolidPeso molecolare:2300.89HIV-1 inhibitor-59
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.Formula:C28H28FN5O3SColore e forma:SolidPeso molecolare:533.62Tipranavir
CAS:Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzymeFormula:C31H33F3N2O5SPurezza:99.85%Colore e forma:White SolidPeso molecolare:602.66Ref: TM-T4578
1mg69,00€5mg147,00€1mL*10mM (DMSO)192,00€10mg260,00€25mg580,00€50mg888,00€100mg1.485,00€200mg2.008,00€HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormula:C14H10N4O4SPurezza:99.33%Colore e forma:SolidPeso molecolare:330.32NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1407.17Protease Inhibitor Library
A unique collection of xnum protease and proteasome inhibitors for research in chemical genomics, and drug screening;Colore e forma:Odour SolidRef: TM-L1100
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaL 754394
CAS:L 754394 is an effective and specific inhibitor of the HIV-1 protease.Formula:C38H47N5O5Colore e forma:SolidPeso molecolare:653.81NNRT-IN-8
NNRT-IN-8 (compound 9K) is a potent non-nucleoside reverse transcriptase inhibitor, exhibiting EC50 values of 0.0014, 0.0041, and 0.0077 µM against HIV-1WT, K103N, and E138K, respectively.HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Colore e forma:Odour SolidNNRT-IN-12
NNRT-IN-12 (compound 19) is a potent inhibitor of non-nucleoside reverse transcriptase (NNRT), exhibiting an IC50 value of 0.107 μM against WTHIV-1RT. It shows anti-HIV-1 activity with EC50 values of 14.1 nM, 5.03 nM, 7.64 nM, and 27.1 nM against the L100I, K103N, Y181C, and Y188L mutant strains of HIV-1, respectively. Additionally, NNRT-IN-12 demonstrates cytotoxicity.NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formula:C32H31N9O3SColore e forma:SolidPeso molecolare:621.71HIV-IN-2
CAS:HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].Formula:C34H27ClF7N9O3SColore e forma:SolidPeso molecolare:810.14ELDKWA
CAS:ELDKWA, a highly conserved sequence of amino acids located on the ecto-domain of gp41, serves as the epitope for mAb 2F5, a neutralizing monoclonal antibodyFormula:C35H52N8O11Colore e forma:SolidPeso molecolare:760.83Cys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Formula:C67H124N34O14SPurezza:98%Colore e forma:SolidPeso molecolare:1661.99HIV p17 Gag (77-85)
CAS:Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Formula:C44H72N10O15Purezza:98%Colore e forma:SolidPeso molecolare:981.1Carbovir triphosphate
CAS:Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].Formula:C11H16N5O11P3Colore e forma:SolidPeso molecolare:487.19AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormula:C67H57N7O23Colore e forma:SolidPeso molecolare:1328.2Aureothin
CAS:Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).Formula:C22H23NO6Colore e forma:SolidPeso molecolare:397.42
