Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 475 prodotti per "Proteasi HIV".
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
HIV-1 inhibitor-74
HIV-1inhibitor-74 (compound 10c) is a potent inhibitor of HIV-1, displaying an EC50 of 0.0047 µM against HIV-1IIIB. It exhibits cytotoxic properties and effectively inhibits the activity of WTHIV-1RT with an IC50 of 0.134 µM. Additionally, HIV-1inhibitor-74 demonstrates broad-spectrum anti-HIV-1 activity.Formula:C28H31N9O2SColore e forma:SolidPeso molecolare:557.67HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Colore e forma:Odour SolidMPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formula:C126H201N35O33SPurezza:98%Colore e forma:SolidPeso molecolare:2766.22Globotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Formula:C60H113NO18Colore e forma:SolidPeso molecolare:1136.553(-)-Rabdosiin
CAS:(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].Formula:C36H30O16Colore e forma:SolidPeso molecolare:718.61VIR-165
VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.Formula:C109H158N22O25S2Purezza:98%Colore e forma:SolidPeso molecolare:2240.7AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormula:C67H57N7O23Colore e forma:SolidPeso molecolare:1328.2Peptide T
CAS:Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.Formula:C35H55N9O16Purezza:98%Colore e forma:SolidPeso molecolare:857.86HIV-1 inhibitor-80
HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.Formula:C26H19N7OColore e forma:SolidPeso molecolare:445.475SDZ 283-910
CAS:SDZ 283-910 is used as a statine-derived inhibitor.Formula:C46H59N5O9Purezza:98%Colore e forma:SolidPeso molecolare:826.004HIV-IN-2
CAS:HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].Formula:C34H27ClF7N9O3SColore e forma:SolidPeso molecolare:810.14Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Colore e forma:Odour SolidRef: TM-L1100
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiesta(2S,5S)-Censavudine
(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.Formula:C12H12N2O4Colore e forma:SolidPeso molecolare:248.23NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1407.17Tenofovir-C3-O-C15-CF3 ammonium
CAS:Tenofovir-C3-O-C15-CF3 (ammonium) has a longer half-life and stronger anti-HIV action, improving pharmacokinetics in vivo.Formula:C28H52F3N6O5PColore e forma:SolidPeso molecolare:640.73BNM-III-170
CAS:BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.Formula:C25H26ClF7N6O6Colore e forma:SolidPeso molecolare:674.96HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Colore e forma:Odour SolidGLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formula:C102H194N40O20Purezza:98%Colore e forma:SolidPeso molecolare:2300.89GRL-07524
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.Colore e forma:Odour SolidHIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormula:C26H24N6O2Colore e forma:SolidPeso molecolare:452.51
