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Proteasi HIV

Proteasi HIV

Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.

Trovati 502 prodotti di "Proteasi HIV"

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  • Clavirolide L


    Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without
    Formula:C20H28O3
    Colore e forma:Solid
    Peso molecolare:316.43
  • MB-66


    MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.
    Colore e forma:Odour Liquid
  • CTP518

    CAS:
    CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.
    Formula:C38H52N6O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:719.95
  • (2S,5S)-Censavudine


    (2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.
    Formula:C12H12N2O4
    Colore e forma:Solid
    Peso molecolare:248.23
  • (+)-Carbovir triphosphate

    CAS:
    (+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.
    Formula:C11H16N5O11P3
    Colore e forma:Solid
    Peso molecolare:487.19
  • Lopinavir Metabolite M-1

    CAS:
    Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.
    Formula:C37H46N4O6
    Colore e forma:Solid
    Peso molecolare:642.78
  • Peptide T

    CAS:
    Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.
    Formula:C35H55N9O16
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:857.86
  • CI-39

    CAS:
    CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.
    Formula:C19H18N2O4
    Colore e forma:Solid
    Peso molecolare:338.36
  • HIV-1 protease-IN-4


    HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.
    Formula:C48H69N7O11
    Colore e forma:Solid
    Peso molecolare:920.1
  • QYL-685

    CAS:
    QYL-685 is a methylenecyclopropane nucleoside analog.
    Formula:C20H24N7O5P
    Colore e forma:Solid
    Peso molecolare:473.42
  • HIV-1 inhibitor-58


    HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type
    Formula:C26H24N6O2
    Colore e forma:Solid
    Peso molecolare:452.51
  • GLR-19

    CAS:
    GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].
    Formula:C102H194N40O20
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2300.89
  • KRL74

    CAS:
    KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 μM and a Kd of 11.9 μM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 μM in virus-like particle (VLP) budding assays.
    Formula:C50H61ClN10O9
    Colore e forma:Solid
    Peso molecolare:981.53
  • ICeD-2


    ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.
    Formula:C20H29N3O
    Colore e forma:Solid
    Peso molecolare:327.46
  • Carbovir triphosphate

    CAS:
    Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].
    Formula:C11H16N5O11P3
    Colore e forma:Solid
    Peso molecolare:487.19
  • VIR-165


    VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.
    Formula:C109H158N22O25S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2240.7
  • NF279

    CAS:
    P2X1 antagonist
    Formula:C49H36N6Na6O23S6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1407.17
  • Indoline

    CAS:
    Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    Formula:C8H9N
    Colore e forma:Clear To Yellow Liquid
    Peso molecolare:119.16
  • Salvianan A

    CAS:
    <p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>
    Formula:C20H17NO2
    Colore e forma:Solid
    Peso molecolare:303.35
  • HIV-IN-2

    CAS:
    HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].
    Formula:C34H27ClF7N9O3S
    Colore e forma:Solid
    Peso molecolare:810.14