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Segnalazione PI3K/Akt/mTOR

Segnalazione PI3K/Akt/mTOR

Gli inibitori della segnalazione PI3K/Akt/mTOR sono composti che bersagliano le vie della fosfoinositide 3-chinasi (PI3K), della chinasi Akt e del bersaglio della rapamicina nei mammiferi (mTOR). Queste vie sono regolatori critici della crescita cellulare, della sopravvivenza, del metabolismo e dell'autofagia, rendendole bersagli chiave nella ricerca sul cancro e nei disturbi metabolici. Inibendo queste vie è possibile aiutare a controllare la crescita e la proliferazione tumorale, offrendo potenziali strategie terapeutiche per vari tipi di cancro e altre malattie caratterizzate da una segnalazione cellulare disfunzionale. Presso CymitQuimica, offriamo una vasta selezione di inibitori PI3K/Akt/mTOR di alta qualità per supportare la tua ricerca in oncologia, segnalazione cellulare e malattie metaboliche.

Sottocategorie di "Segnalazione PI3K/Akt/mTOR"

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Trovati 1034 prodotti di "Segnalazione PI3K/Akt/mTOR"

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  • Logo CymitQuimica
    Targetmol
    + Info

    Anti-EGFR Monoclonal Antibody

    <p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>
    Purezza:> 95% as determined by SDS-PAGE.
    Colore e forma:Liquid
    Peso molecolare:150 kDa

    Ref: TM-TMAZ-0108

  • Logo CymitQuimica
    Targetmol
    + Info

    Anti-EGFR Monoclonal Antibody-Biotin

    Antibody Type: Rabbit Monoclonal<br> Application: FCM<br> Reactivity: Human
    Purezza:> 95% as determined by SDS-PAGE.
    Colore e forma:Liquid
    Peso molecolare:150 kDa

    Ref: TM-TMAZ-0108B

  • Osimertinib
    Targetmol
    + Info

    Osimertinib

    CAS:
    Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.
    Formula:C28H33N7O2
    Purezza:99.32% - >99.99%
    Colore e forma:Solid
    Peso molecolare:499.61

    Ref: TM-T2490

  • CHIR-99021
    Targetmol
    + Info

    CHIR-99021

    CAS:
    View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.
    Formula:C22H18Cl2N8
    Purezza:97.94% - ≥95%
    Colore e forma:Solid
    Peso molecolare:465.34

    Ref: TM-T2310

  • AZD-8835
    Targetmol
    + Info

    AZD-8835

    CAS:
    <p>AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).</p>
    Formula:C22H31N9O3
    Purezza:98.22% - 99.88%
    Colore e forma:Solid
    Peso molecolare:469.54

    Ref: TM-T6774

  • PIK-75 hydrochloride
    Targetmol
    + Info

    PIK-75 hydrochloride

    CAS:
    <p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>
    Formula:C16H14BrN5O4S·HCl
    Purezza:97.82%
    Colore e forma:Solid
    Peso molecolare:488.74

    Ref: TM-T2287

  • TX1-85-1
    Targetmol
    + Info

    TX1-85-1

    CAS:
    TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.
    Formula:C32H36N8O3
    Purezza:97.16% - 98.12%
    Colore e forma:Solid
    Peso molecolare:580.68

    Ref: TM-T17182

  • Sulforaphene
    Targetmol
    + Info

    Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Formula:C6H9NOS2
    Purezza:97.55% - 99.19%
    Colore e forma:Slightly Yellowish Liquid
    Peso molecolare:175.27

    Ref: TM-TL0016

  • GSK2334470
    Targetmol
    + Info

    GSK2334470

    CAS:
    <p>GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.</p>
    Formula:C25H34N8O
    Purezza:99.57% - 99.87%
    Colore e forma:Solid
    Peso molecolare:462.59

    Ref: TM-T2348

  • Tyrphostin B44, (+) enantiomer
    Targetmol
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    Tyrphostin B44, (+) enantiomer

    CAS:
    Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)
    Formula:C18H16N2O3
    Purezza:97.18%
    Colore e forma:Solid
    Peso molecolare:308.33

    Ref: TM-T22450

  • RSVA405
    Targetmol
    + Info

    RSVA405

    CAS:
    <p>RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor</p>
    Formula:C17H20N4O2
    Purezza:99.30%
    Colore e forma:Solid
    Peso molecolare:312.37

    Ref: TM-T8476

  • Trastuzumab
    Targetmol
    + Info

    Trastuzumab

    CAS:
    Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.
    Purezza:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%
    Colore e forma:Liquid
    Peso molecolare:Approximately 145.53 kDa

    Ref: TM-T9912

  • AZ-5104
    Targetmol
    + Info

    AZ-5104

    CAS:
    AZ5104 is a potent EGFR inhibitor.
    Formula:C27H31N7O2
    Purezza:98.40% - 99.59%
    Colore e forma:Solid Powder
    Peso molecolare:485.58

    Ref: TM-T2491

  • GNE-317
    Targetmol
    + Info

    GNE-317

    CAS:
    GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).
    Formula:C19H22N6O3S
    Purezza:98.42% - 99.54%
    Colore e forma:Solid
    Peso molecolare:414.48

    Ref: TM-T6845

  • TGX-221
    Targetmol
    + Info

    TGX-221

    CAS:
    <p>TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.</p>
    Formula:C21H24N4O2
    Purezza:99.68% - >99.99%
    Colore e forma:Solid
    Peso molecolare:364.44

    Ref: TM-T2661

  • Autogramin-1
    Targetmol
    + Info

    Autogramin-1

    CAS:
    <p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>
    Formula:C23H27N5O5S
    Purezza:97.69% - 99.25%
    Colore e forma:Solid
    Peso molecolare:485.56

    Ref: TM-T10413

  • AEE788
    Targetmol
    + Info

    AEE788

    CAS:
    <p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>
    Formula:C27H32N6
    Purezza:98% - >99.99%
    Colore e forma:Solid
    Peso molecolare:440.58

    Ref: TM-T2116

  • AG-1557 hydrochloride (189290-58-2(free base))
    Targetmol
    + Info

    AG-1557 hydrochloride (189290-58-2(free base))

    AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
    Formula:C16H15ClIN3O2
    Purezza:98.64%
    Colore e forma:Solid
    Peso molecolare:443.66

    Ref: TM-T4694

  • Voxtalisib
    Targetmol
    + Info

    Voxtalisib

    CAS:
    Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
    Formula:C13H14N6O
    Purezza:98.21% - 99.69%
    Colore e forma:Solid
    Peso molecolare:270.29

    Ref: TM-T7014

  • IM-12
    Targetmol
    + Info

    IM-12

    CAS:
    <p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>
    Formula:C22H20FN3O2
    Purezza:99.42% - >99.99%
    Colore e forma:Solid
    Peso molecolare:377.41

    Ref: TM-T2261