PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 237 prodotti per "PI3K".
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P110δ-IN-1
CAS:P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).Formula:C31H40N8O3SPurezza:99.75%Colore e forma:SolidPeso molecolare:604.77WYE-687
CAS:WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).Formula:C28H32N8O3Purezza:99.93%Colore e forma:SolidPeso molecolare:528.61Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formula:C16H13ClO4SPurezza:98.85% - 98.96%Colore e forma:SolidPeso molecolare:336.79Ref: TM-T13862
1mg43,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg113,00€25mg177,00€50mg295,00€100mg477,00€200mg677,00€NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Formula:C29H27F2N5O5S2Purezza:99.58%Colore e forma:SolidPeso molecolare:627.68Ref: TM-T16355
2mg39,00€5mg60,00€1mL*10mM (DMSO)84,00€10mg87,00€25mg159,00€50mg231,00€100mg355,00€200mg505,00€Safingol hydrochloride
CAS:Safingol hydrochloride (L-threo-dihydrosphingosine hydrochloride) is a PKC-specific inhibitor that inhibits PKC and PI3k and induces cancer cell death.Formula:C18H40ClNO2Purezza:99.71% - 99.87%Colore e forma:SolidPeso molecolare:337.969Tenalisib
CAS:Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)Formula:C23H18FN5O2Purezza:99.71%Colore e forma:SolidPeso molecolare:415.42PI4KIIIbeta-IN-9
CAS:PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .Formula:C23H25N3O5S2Purezza:97.18%Colore e forma:SolidPeso molecolare:487.59Ref: TM-T12469
1mg49,00€5mg111,00€1mL*10mM (DMSO)122,00€10mg166,00€25mg290,00€50mg406,00€100mg532,00€Inavolisib
CAS:Inavolisib (GDC-0077) is an orally available selective PI3Kα inhibitor with an IC50 value of 0.038 nM.Cost-effective and quality-assured.Formula:C18H19F2N5O4Purezza:97.36% - 99.90%Colore e forma:SolidPeso molecolare:407.37Ref: TM-T15375
1mg84,00€5mg200,00€10mg353,00€1mL*10mM (DMSO)383,00€25mg602,00€50mg982,00€100mg1.603,00€200mg2.142,00€CGS 15943
CAS:CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.Formula:C13H8ClN5OPurezza:97.4%Colore e forma:SolidPeso molecolare:285.69Ref: TM-T14944
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg82,00€25mg147,00€50mg222,00€100mg334,00€200mg494,00€Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purezza:99.55% - 99.95%Colore e forma:White SolidPeso molecolare:407.04Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormula:C25H35N7O9S4Purezza:99.63%Colore e forma:SolidPeso molecolare:705.85IPI-3063
CAS:IPI-3063 is an effective and selective inhibitor of PI3K p110δ (IC50: 2.5 ± 1.2 nM).Formula:C25H25N7O2Purezza:98.00%Colore e forma:SolidPeso molecolare:455.51Ref: TM-T15592
1mg44,00€2mg60,00€5mg99,00€1mL*10mM (DMSO)107,00€10mg166,00€25mg323,00€50mg447,00€100mg610,00€PI4KIIIbeta-IN-10
CAS:PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).Formula:C22H25N3O5S2Purezza:99.76%Colore e forma:SolidPeso molecolare:475.58Ref: TM-T12468
1mg75,00€5mg156,00€1mL*10mM (DMSO)164,00€10mg241,00€25mg399,00€50mg532,00€100mg750,00€200mg1.009,00€Parsaclisib
CAS:Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)Formula:C20H22ClFN6O2Purezza:98.59%Colore e forma:SolidPeso molecolare:432.88Ref: TM-T12367
1mg138,00€5mg289,00€1mL*10mM (DMSO)318,00€10mg434,00€25mg763,00€50mg1.054,00€100mg1.423,00€Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formula:C15H22N2OPurezza:99.55%Colore e forma:White SolidPeso molecolare:246.35Copanlisib dihydrochloride
CAS:Copanlisib dihydrochloride: ATP-competitive PI3K inhibitor, potent for PI3Kα/δ/β/γ, antitumor, 2000x selectivity over other kinases except mTOR.Formula:C23H30Cl2N8O4Purezza:99.05% - 99.16%Colore e forma:SolidPeso molecolare:553.44ARUK2001607
CAS:ARUK2001607 selectively inhibits PI5P4Kγ (Kd=7.1 nM) with high selectivity over 150+ kinases.Formula:C14H13N3O2S2Purezza:99.75%Colore e forma:SolidPeso molecolare:319.40PI3Kα-IN-25
PI3Kα-IN-25 (Compound Djh1) is a selective inhibitor of PI3Kα, suitable for research in triple-negative breast cancer.Formula:C21H19ClN4O4Colore e forma:SolidPeso molecolare:426.853PI3K-IN-57
PI3K-IN-57 (Compound 4a) is a PI3K inhibitor that shows strong inhibitory effects on the proliferation of HeLa tumor ectopic xenografts in vivo. It holds promise for anticancer agent research.Colore e forma:Odour SolidPI3K-AKT-mTOR Compound Library
A unique collection of xnum compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;Colore e forma:Odour SolidRef: TM-L1300
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