PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 237 prodotti per "PI3K".
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740 Y-P acetate
740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-Formula:C143H226N43O41PS3Purezza:99.92%Colore e forma:SoildPeso molecolare:3330.79PI3Kδ-IN-12
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities with pKi values of 8.0 for PI3Kδ, 6.5 for PI3Kγ, 6.4Formula:C20H15Cl2N5O3Purezza:98%Colore e forma:SolidPeso molecolare:444.27GSK251
CAS:GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with a unique binding mode.Formula:C29H37FN6O4SPurezza:99.8%Colore e forma:White SolidPeso molecolare:584.71(3S)-GSK-F1
CAS:(3S)-GSK-F1 is a selective small molecule inhibitor of Type III Phosphatidylinositol 4‑Kinase Alpha (PI4KIIIα), pIC50=8.3.Formula:C27H18F5N5O4SPurezza:99.04%Colore e forma:SolidPeso molecolare:603.52Ref: TM-T67837
100mgPrezzo su richiesta1mg70,00€5mg133,00€1mL*10mM (DMSO)182,00€10mg210,00€25mg371,00€50mg532,00€IHMT-PI3Kδ-372 S-isomer
CAS:IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM.Formula:C26H23F2N7O2Purezza:99.97%Colore e forma:White SolidPeso molecolare:503.5Ref: TM-T60196
1mg109,00€2mg163,00€5mg241,00€1mL*10mM (DMSO)294,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€Duvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor.Formula:C22H18Cl2N6OPurezza:99.86% - 99.88%Colore e forma:White SolidPeso molecolare:453.32Ref: TM-T11129L
1mg296,00€5mg718,00€1mL*10mM (DMSO)895,00€10mg982,00€25mg1.485,00€50mg2.008,00€100mg2.637,00€PROTAC PI3K/110β degrader-1
CAS:PROTACPI3K/110β degrader-1 (J-9) acts as a PROTAC degrader specifically targeting PI3K/110β.Formula:C51H65N9O9SColore e forma:SolidPeso molecolare:980.18PI3K-IN-46
CAS:PI3K-IN-46 is a specific inhibitor of PI3Kγ.Formula:C13H9N3OSPurezza:97.26%Colore e forma:SolidPeso molecolare:255.3Ref: TM-T64392
1mg62,00€1mL*10mM (DMSO)133,00€5mg149,00€10mg213,00€25mg319,00€50mg450,00€100mg605,00€ARUK2001607
CAS:ARUK2001607 selectively inhibits PI5P4Kγ (Kd=7.1 nM) with high selectivity over 150+ kinases.Formula:C14H13N3O2S2Purezza:99.75%Colore e forma:SolidPeso molecolare:319.40GSK2292767 FA
GSK2292767 FA: potent PI3Kδ inhibitor, pIC50=10.1, 500x selectivity, for respiratory research.Formula:C25H30N6O7SPurezza:99.52%Colore e forma:SolidPeso molecolare:558.61PI3K-IN-57
PI3K-IN-57 (Compound 4a) is a PI3K inhibitor that shows strong inhibitory effects on the proliferation of HeLa tumor ectopic xenografts in vivo. It holds promise for anticancer agent research.Colore e forma:Odour SolidPenetratin-PI3Kγ(126-150)
Penetratin-PI3Kγ(126-150) is a peptide inhibitor of PI3Kγ that plays a significant role in respiratory diseases.Formula:C229H362N76O57SColore e forma:SolidPeso molecolare:5120.74849IHMT-PI3K-315
IHMT-PI3K-315 (20e) serves as a potent, selective inhibitor of PI3Kγ/δ, exhibiting IC 50 values of 4.0 nM for PI3Kγ and 9.1 nM for PI3Kδ. Additionally, it demonstrates antitumor activity.Formula:C22H20F2N6O4Colore e forma:SolidPeso molecolare:470.43Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Colore e forma:Odour SolidRef: TM-L1600
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaBAY1082439
CAS:BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2].Formula:C25H30N6O5Purezza:98%Colore e forma:White SolidPeso molecolare:494.54PI3K-AKT-mTOR Compound Library
A unique collection of xnum compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;Colore e forma:Odour SolidRef: TM-L1300
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaUmbralisib R-enantiomer
CAS:Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202.Formula:C31H24F3N5O3Purezza:97.34%Colore e forma:SolidPeso molecolare:571.55Ref: TM-T13140
1mg177,00€5mg432,00€1mL*10mM (DMSO)532,00€10mg620,00€25mg1.108,00€50mg1.431,00€100mg1.783,00€PI3Kα-IN-25
PI3Kα-IN-25 (Compound Djh1) is a selective inhibitor of PI3Kα, suitable for research in triple-negative breast cancer.Formula:C21H19ClN4O4Colore e forma:SolidPeso molecolare:426.853FDA-Approved Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.Colore e forma:LiquidRef: TM-L1610
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaPI3K-IN-47
PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, exhibiting inhibitory concentration (IC50)Formula:C50H46F4N8O8S2Purezza:98%Colore e forma:SolidPeso molecolare:1027.07
