PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 235 prodotti per "PI3K".
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Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Formula:C31H24F3N5O3Purezza:99.56% - 99.56%Colore e forma:White SolidPeso molecolare:571.55Ref: TM-T4976
1mg46,00€2mg62,00€5mg90,00€1mL*10mM (DMSO)114,00€10mg166,00€25mg324,00€50mg425,00€100mg623,00€AZD-8835
CAS:AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).Formula:C22H31N9O3Purezza:98.22% - 99.88%Colore e forma:SolidPeso molecolare:469.54AS-604850
CAS:AS-604850: ATP-competitive PI3Kγ inhibitor, IC50 250 nM, 18x > PI3Kα, 80x > PI3Kδ/β.Formula:C11H5F2NO4SPurezza:99.65%Colore e forma:SolidPeso molecolare:285.22PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Formula:C14H16ClN3O4S2Purezza:97.72%Colore e forma:SolidPeso molecolare:389.88Ref: TM-T2616
1mg42,00€5mg85,00€1mL*10mM (DMSO)94,00€10mg105,00€25mg200,00€50mg305,00€100mg427,00€200mg613,00€CH5132799
CAS:CH5132799 has been used in trials studying the treatment of Solid Tumors.Formula:C15H19N7O3SPurezza:99.41% - 99.87%Colore e forma:SolidPeso molecolare:377.42Ref: TM-T2619
1mg60,00€2mg92,00€5mg137,00€10mg215,00€25mg399,00€50mg590,00€100mg838,00€500mg1.693,00€Seletalisib
CAS:Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).Formula:C23H14ClF3N6OPurezza:99.81%Colore e forma:SolidPeso molecolare:482.85Ref: TM-TQ0044
1mg54,00€2mg77,00€5mg114,00€1mL*10mM (DMSO)119,00€10mg178,00€25mg313,00€50mg447,00€100mg625,00€α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Formula:C18H30O2Purezza:97.05% - 99.81%Colore e forma:Transparent LiquidPeso molecolare:278.43GSK2636771
CAS:GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, andFormula:C22H22F3N3O3Purezza:98.58% - ≥95%Colore e forma:SolidPeso molecolare:433.42Ref: TM-T2073
1mg40,00€2mg54,00€5mg84,00€1mL*10mM (DMSO)84,00€10mg142,00€25mg240,00€50mg340,00€100mg518,00€Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formula:C21H24ClN7OPurezza:97.04%Colore e forma:SolidPeso molecolare:425.91Ref: TM-T7015
1mg43,00€2mg56,00€5mg88,00€1mL*10mM (DMSO)96,00€10mg124,00€25mg207,00€50mg333,00€100mg477,00€SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purezza:99.42% - 99.99%Colore e forma:SolidPeso molecolare:443.85PIK-90
CAS:PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .Formula:C18H17N5O3Purezza:98.25% - ≥95%Colore e forma:SolidPeso molecolare:351.36A66
CAS:A66 is a specific and effective p110α inhibitor(IC50=32 nM).Formula:C17H23N5O2S2Purezza:99.51% - ≥95%Colore e forma:SolidPeso molecolare:393.53Ref: TM-T2418
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg79,00€25mg137,00€50mg234,00€100mg344,00€200mg485,00€Linperlisib
CAS:Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3KδFormula:C28H37FN6O5SPurezza:99.01%Colore e forma:SolidPeso molecolare:588.69Ref: TM-T6330
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)87,00€10mg90,00€25mg192,00€50mg295,00€100mg462,00€Vps34-IN-4
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formula:C21H25N7OPurezza:98.6%Colore e forma:SolidPeso molecolare:391.47Ref: TM-T7944
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg378,00€50mg537,00€100mg713,00€200mg982,00€CAY10505
CAS:CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Formula:C14H8FNO3SPurezza:99.69% - 99.74%Colore e forma:SolidPeso molecolare:289.28Ref: TM-T6433
10mg34,00€1mL*10mM (DMSO)38,00€25mg52,00€50mg96,00€100mg144,00€200mg205,00€500mg350,00€GDC-0326
CAS:GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).Formula:C19H22N6O3Purezza:99.35% - >99.99%Colore e forma:SolidPeso molecolare:382.42Ref: TM-T3985
1mg34,00€2mg50,00€1mL*10mM (DMSO)88,00€5mg90,00€10mg146,00€25mg241,00€50mg385,00€100mg560,00€AZD8186
CAS:AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).Formula:C24H25F2N3O4Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:457.47Ref: TM-T6773
2mg43,00€5mg63,00€1mL*10mM (DMSO)69,00€10mg94,00€25mg165,00€50mg289,00€100mg477,00€500mg1.063,00€Selective PI3Kδ Inhibitor 1
CAS:Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).Formula:C23H20FN7OPurezza:97.96%Colore e forma:SolidPeso molecolare:429.45Pilaralisib analogue
CAS:Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.Formula:C21H16N6O2S2Purezza:99.3% - 99.72%Colore e forma:SolidPeso molecolare:448.52Ref: TM-T2377
2mg35,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg84,00€25mg132,00€50mg205,00€100mg354,00€200mg460,00€AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purezza:99.87% - 99.95%Colore e forma:SolidPeso molecolare:408.45
