Eterocicli con azoto (N)

Applications Benzimidazole-4,5,6,7-d4 (CAS# 64531-29-9) is a useful isotopically labeled research compound.

Applications 3-chloropyridazine hydrochloride (cas# 856847-77-3) is a useful research chemical.

Applications (αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid is an intermediate used to prepare Cephalosporin derivatives with activities against both Gram-positive and Gram-negative bacteria.
References Albrecht, H., et al.: J. Med. Chem., 37, 400 (1994)

Applications 4-Pyridinecarboxamide 1-Oxide (cas# 38557-82-3) is a compound useful in organic synthesis.

Applications N-[1-(pyridin-3-yl)ethyl]hydroxylamine (cas# 887411-44-1) is a useful research chemical.

Applications Reagent used to prepare biosynthetic polymer surfactants designed for shear-stable endothelialization.
References Schaefer, A., et al.: J. Bacteriol., 178, 2897 (1996), Ruegsegger, M., et al.: J. Biomed. Mat. Res., 56, 159 (2001), Abdu-Allah, H., et al.: J. Med. Chem., 51, 6665 (2008), Georgiades, S., et al.: Bioorg. Med. Chem. Lett., 18, 3117 (2008),

Applications 4-Pyrazoleboronic Acid Pinacol Ester is used in the preparation of Rho kinase (ROCK) inhibitors as wella s other biologically active compounds.
References Chowdhury, S. et al.: Bioorg. Med. Chem. Lett., 21, 7107 (2011);

Applications A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kenner, G.W., Seely, J., J. Am. Chem. Soc., 94, 3259 (1972), Castro, B., et al.: Tetrahedron Lett., 1219 (1975)

Applications 4-Chloro-6-phenylpyrimidine (cas# 3435-26-5) is a useful research chemical.

Applications 2,4-Dichloro-5-trifluoromethylpyrimidine is a reactant in the preparation of pyrimidine derivatives as inhibitors of gene ALK protein Kinase phosphorylating kinase and as cell proliferation inhibitors.
References Yang, E.H., et. al.: Bull. Korean Chem. Soc., 34, 3129 (2013)

Applications 2-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).
References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)

Applications (S)-3-Aminopiperidin-2-one-D6 is a labelled analogue of (S)-3-Aminopiperidin-2-one (A627940). (S)-3-Aminopiperidin-2-one, is an building block , used in the synthesis of various pharmaceutical compounds. It is an intermediate in the synthesis of calpinactam derivatives, possessing antimycobacterial activity.
References Kenichiro, N., et al.: Bioorg. Med. Chem. Lett., 22, 7739 (2012);

Applications 2,5-Diacetamido-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one (cas# 22365-29-3) is a compound useful in organic synthesis.

Applications tert-butyl 2,2-dimethyl-3-oxopyrrolidine-1-carboxylate (cas# 1215295-96-7) is a useful research chemical.

Applications 2-Chloro-4-ethylpyridine (cas# 40325-11-9) is a compound useful in organic synthesis.

Stability Moisture Sensitive, Air Sensitive
Applications pyrimidine-2-sulfonyl fluoride (cas# 35762-87-9) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-(Hydroxymethyl)pyridine N-Oxide (cas# 10242-36-1) is a compound useful in organic synthesis.

Applications 2-Chloro-3-nitropyridine (cas# 5470-18-8) is a useful research chemical.

Applications Phenyl (4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamate Hydrochloride is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
References Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);

Applications 1-(2-Phenylethyl)piperazine is used to prepare non-imidazole human histamine H4 receptor antagonists. it is also used to synthesize imidazopyridine derivatives as inhibitors of Aurora kinases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jablonowski, J., et al.: J. Med. Chem., 46, 3957 (2003); Bavetsias, V., et al.: Bioorg. Med. Chem. Lett., 17, 6567 (2007)

Applications 4-Hydroxypiperidine-D4 is an isotope labelled form of 4-Hydroxypiperidine (H950845), a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.
References Yang, D. et al.: Macromol., 35, 5304 (2002); Harrison, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 2463 (1999);

Applications Pyridine-15N, is the labeled analogue of Pyridine (P991280), a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions.
References Egyed, J. et al.: Bull. Soc. Chim. Fra., 11, 3014 (1973); Li, Y. et al.: Wuli HUa. Xueb., 14, 1048 (1998);

Applications 1-(pyridin-4-yl)-1H-pyrazole-3-carboxylic acid (cas# 911463-81-5) is a useful research chemical.

Applications 4-Benzylpyridine is a benzylpyridine with antifungal properties. 4-Benzylpyridine has been used as a reactant in the synthesis of bis(alkylpyridinium)alkanes as antifungal agents.
References Takeshiba, H. et al.: Sank. Kenk. Nen., 23, 225 (1971)

Applications 3-​Methoxy-​4-​methyl-​1H-​1,​2,​4-​triazol-​5(4H)​-​one Hydrate, is a Triazole (T767410) derivative that was used in microwave synthesis of 1,2,4-triazolone derivatives possessing antifungal activity. 3-​Methoxy-​4-​methyl-​1H-​1,​2,​4-​triazol-​5(4H)​-​one is also a key intermediate for sulfonylurea herbicides, such as flucarbazone.
References Su, J., Shang, Z.: Nongyao, 49, 563 (2010); Sun, N., et al.: BioMed Res. Int., 1 (2015);

Applications 5-phenyl-1H-1,2,3-triazole-4-carboxylic acid (cas# 830-78-4) is a useful research chemical.

Applications 2,2-Dimethylpiperazine is a chemical reagent used in the preparation of non-covalent NAAA inhibitors used as a protective agent for the development of multiple sclerosis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Migliore, M. et al.: Angew. Chem. Int. Ed., 55, 11193 (2016);

Applications PIPERONYL ACETONE (cas# 55418-52-5) is a useful research chemical.

Applications 3-Piperidinesulfonic Acid is an isomer of piperidine-4-sulfonic acid, a new specific GABA agonist.
References Krogsgaard-Larsen, P., et al.: J. Neurochem., 34, 756 (1980)

Applications A labelled Voriconazole (V760000) impurity.
References Rieke, R., et al.: Science, 246, 1260 (1989), Dickinson, R., et al.: Bioorg. Med. Chem. Lett., 6, 2031 (1996),

Applications 6-Methoxy-4-pyrimidinamine is used in the synthesis of carbamothiolacrylamides as selective EP2 antagonists in the treatment of neurodegenerative peripheral diseases. Also used in the preparation of PARP-1 inhibitors.
References Ganesh, T. et al.: ACS Med. Chem. Lett., 4, 616 (2013); Rhee, H. et al.: Bioorg, Med. Chem., 17, 7537 (2009);

Applications 3-Bromo-5-(1-hydroxyethyl)pyridine

Applications 4,6-Dichloropyrazolo[3,4-d]pyrimidine (cas# 42754-96-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1-Acetyl-1H-pyrazole-4-boronic acid, pinacol ester

Applications 1-(2-Chlorophenyl)-3-phenyl-4-(m-tolyl)-6,8-dihydro-1H-pyrazolo[3,4-e][1,4]thiazepin-7(4H)-one is an intermediate for the synthesis of 1-(2-Chlorophenyl)-1,4,6,7-tetrahydro-4-(3-methylphenyl)-7-oxo-3-phenyl-8H-pyrazolo[3,4-e][1,4]thiazepine-8-acetic Acid (C597045).

Applications N-Methylpiperidinyl-2-methyl Benzilate (cas# 94909-90-7) is a compound useful in organic synthesis.

Applications Bimodal effect of the picolinic acid derivatives on the rate of wheat and pea germination.
References Hamaker, J., et al.: Science, 141, 363 (1963),

Applications Methyl 5-Oxopyrrolidine-3-carboxylate has been used as a reactant in the synthesis of tert-butyloxycarbonyl protected 4,5-methano-β-proline.
References Tymtsunik, A.V., et. al.: Tetrahedron Lett., 55, 3312 (2014)

Applications 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine Dihydrochloride is a useful reagent for synthesis of the bicyclic secondary amines via dimethylaminomethylene derivatives of 3-pyrrolidone and 3-piperidone.
References Fukui, H., et al.: Heterocycles, 56, 257 (2002);

Stability Hygroscopic
Applications 2-Fluoro-6-(trifluoromethyl)pyridine-3-boronic acid

Applications 1-(2-Ethoxyphenyl)piperazine monohydrochloride 99 (cas# 83081-75-8) is a useful research chemical.

Applications 4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride (cas# 62002-31-7) is a useful research chemical.

Applications 6-Chloro-3-Fluoro-2-Iodopyridine (cas# 1211590-36-1) is a useful research chemical.

Applications 4-amino-1,2,4-triazolidine-3,5-dione (cas# 21531-96-4) is a useful research chemical.

Applications 2-(1-Adamantyl)-4,5-dihydro-1H-imidazole (cas# 52725-79-8) is a useful research chemical.

Applications 2-Benzoylpyrrole (cas# 7697-46-3) is a compound useful in organic synthesis.

Applications A useful synthetic intermediate.

Applications 5-(4-Bromo-2-methylphenyl)-1H-tetrazole (cas# 1007128-19-9) is a useful research chemical.

Applications 5-Amino-4H-1,2,4-triazole-3-carboxylic Acid is a building block used in the synthesis of purine nucleotide analogs by a promiscuous hypoxanthine phosphoribosyltransferase.
References Scism, R.A., et. al.: Org. Lett., 9, 4179 (2007)

Applications (1-Ethyl-piperidin-3-yl)-carbamic Acid tert-Butyl Ester is an intermediate in the synthesis of 4-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide (A609495), which is an impurity of Amisulpride (A633250). Amisulpride EP Impurity G.
References Elslager, E.F., et al.: J. Med. Chem., 24, 127 (1981)

Applications Methyl 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (cas# 1083181-12-7) is a useful research chemical.

Applications 2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity.
References Prochazkova, E. et al.: Free Radical Res., 46, 61 (2011); Lin, S. et al.: J. Med. Chem., 22, 741 (1979)

Applications n-Hexadecylpyridinium-d5 Bromide (CAS# 143715-91-7) is a useful isotopically labeled research compound.

Applications 2-Isopropylthio-5-trifluoromethylpyridine-3-boronic acid

Applications 1-tert-butyl-1H-pyrrole-3-carboxylic acid (cas# 1266364-46-8) is a useful research chemical.

Applications: 2,7-Dimethyl-[1,4]dioxino[2,3-b:5,6-b']dipyridine is intermediate in the synthesis of compounds used in analytical studies for the presence and formation of dioxin-like compounds in heat-treated chlorpyrifos herbicide, a potential precursor of pyridine analog of 2,3,7,8-Tetrachloro-p-dioxin (T291370).
References Sakiyaama, T., et al.: Organohalogen Compounds, 73, 146 (2011);