Reagenti sintetici

<p>Applications Acetylenedicarboxylic Acid is used as an electrolyte in the fabrication of anodic nanoporous alumina. It is also used as a reagent in the synthesis of several organic compounds including that of derivatives of metronodazole (antibiotic and antiprotozoal medication) which display increased antimicrobial and antiparasitic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kikuchi, T., et al.: Electrochem. Lett., 3, C25 (2014); Al-Masoudi, N., et al.: Monatsh. Chem., 147, 383 (2016);<br></p>

<p>Applications 1,8-Dibromooctane is used as a reagent in the synthesis of novel 7-aminoalkyl-substituted flavonoid derivatives as potential cholinesterase inhibitors.<br>References Luo, W., et al.: Bioorg. Med. Chem., 24, 672 (2016)<br></p>

<p>Applications 4-Methoxynaphthalen-1-ol is a novel antibacterial compound targeting the WalK/WalR two-component signal transduction system of Gram (+) bacteria. walrycin A is a novel human PXR activator, that induces human PXR transcriptional activity. 4-Methoxynaphthalen-1-ol is a WalR inhibitors, a novel antibacterial compound specifically targeting essential WalR response regulator.<br>References Berthier, A., et al.: Toxicol.l Sci., 127, 225 (2012); Gotoh, Y., et al.: J. Antibiot., 63, 127 (2010)<br></p>

<p>Applications Thioisonicotinamide is an impurity of Ethionamide (E890420) with tuberculostatic activity.<br>References Pappalardo, G. et al.: Farm. Ediz. Sco., 22, 808 (1967); Waisser, K. et al.: Cesk.-Slov. Farm., 33, 99 (1984); Devani, M. B. et al.: J. Pharmac. Sci., 43, 1471 (1974);<br></p>

<p>Applications Cerium(IV) trifluoromethanesulfonate, is used as a strong oxidizing agent, in the oxidation of benzyl alcohols and alkylbenzenes to aryl aldehydes and aryl ketones respectively. It can slo be used as a catalyst for high-yield deprotection of tert-butyldimethylsilyl ethers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Imamoto, T., et al.: Chem. Lett., 8, 1445 (1990); Tetrahedron Lett., 43, 5945 (2002).<br></p>

<p>Applications 2-Methyl-5-nitrobenzoic Acid (cas# 1975-52-6) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Benzylethanolamine is used in the synthesis of imidazoles as potent calcitonin (CGRP) antagonists. Also it aids in the preparation of benzofused hydroxamix acids, as useful fragments for the synthesis of histone deacetylase inhibitors.<br>References Tora, G. et al.: Bioorg. Med. Chem. Lett., 23, 5684 (2013); Marastoni, E. et al.: Bioorg. Med. Chem. Lett., 23, 4091 (2013);<br></p>

<p>Applications Sodium Hydrogen Sulfate is used in production of Nickel Hydroxide Electrode material for Alkaline battery.<br>References Naboka, O., et al.: Eur. Pat. Appl., (2020);<br></p>

<p>Applications A chiral derivative of Camphor.<br>References Peng, R., et al.: Biochem. Pharmacol., 35, 1391 (1986), Tanaka, E., et al.: Biochem. Pharmacol., 41, 472 (1991),<br></p>

<p>Applications cis-1-Ethoxy-2-(tributylstannyl)ethene is used in the synthesis of (+)-pleuromutilin (P610500), an antibiotic substance produced by the basidiomycetes Pleurotus mutilus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fazakerley, N.J., et. al.: Chem. Eur. J., 19, 6718 (2013)<br></p>

<p>Applications Chloro(triethylphosphine)gold is an analogue of auranofin. Auranofin and its analogs show antimicrobial activity against multidrug-resistant pathogens<br>References Tizian M. et al.: Chem. Med. Chem. 13(22), 2448-2454 (2018)<br></p>

<p>Applications Titanium(IV) Isopropoxide is used as a catalyst in chemical reactions and photodegredation of pollutants in water and air. Also used in the preparation and operation of polymer solar cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ohno, T. et al.: App. Catal. A., 265, 115 (2004); Kim, J. et al.: Science., 317, 222 (2007);<br></p>

<p>Applications Bariumhydroxidemonohydrate (cas# 22326-55-2) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications Butyl Nitrite is reagent used in the preparation of p-hydroxyphenylpyruvate dioxygenase inhibitors which has herbicidal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Witschel, M., Bioorg. Med. Chem., 17, 4221 (2009)<br></p>

<p>Applications Copper(I) Chloride, has many applications. The main use of copper(I) Chloride is as a precursor to the fungicide copper oxychloride. In organic synthesis, CuCl is used as an initiator of radical reactions such as the hydrostannation of α,β-unsaturated ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wade, L. G., et al.: Org. Chem., 5th Ed., 871 (2003); Ooi, T., et al.: Tetrahedron Lett., 40, 2133 (1999);<br></p>

<p>Applications Potassium Hexamethyldisilazane is used in the preparation of 5-azacytidine, an antineoplastic drug. Also used in the preparation of β3-AR agonists used in anti-stress formulations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vujjini, S. et al.: Org. Proc. Res. Dev., 17, 303 (2013); Xu, F. et al.: Org. Lett., 15, 1342 (2013);<br></p>

<p>Applications 1,1'-(AZODICARBONYL)DIPIPERIDINE (cas# 10465-81-3) is a useful research chemical.<br></p>

<p>Applications 2-(4-Chlorophenyl)ethylamine has been used as a reactant in the preparation of isoalloxazine derivatives as cholinesterase inhibitors with a potential use in Alzheimer therapy.<br>References Kanhed, A.M., et. al.: Bioorg. Chem., 61, 7 (2015)<br></p>

<p>Applications [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium(II), is a palladium catalyst used in chemical synthesis of various compounds.<br></p>

<p>Applications Potassium hydrogen fluoride (cas# 7789-29-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications LITHIUM FLUORIDE (cas# 7789-24-4) is a useful research chemical.<br></p>

<p>Applications (S)-(-)-α-Methylbenzylamine (cas# 2627-86-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-acetylindole (cas# 703-80-0) is a useful research chemical.<br></p>

<p>Applications Bismuth Nitrate Pentahydrate acts as a precursor in the prepoaration of photocatalysts.<br>References Tang, J. et al.: J. Phys. Chem. C., 111, 12779 (2007);<br></p>

<p>Applications (R)-RuCl[(p-cymene)(BINAP)]Cl is a ruthenium BINAP catalysts.<br>References Yue, C., et al.: Yingyong Huagong, 43, 1042 (2014); Bernas, H., et al.: Catal. Sci. Technol., 2, 1901 (2012)<br></p>

<p>Applications Hydrofluoric Acid is a common chemical reagent used as a precursor to most pharmaceutical and high volume fluoride compounds as well as in the oil refinery process. Hydrofluoric acid causes skin burns if contact with skin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamashita M. et al.; Crit. Care. Med., 29, 1575 (2001); Stahl, K. et al.: Ind. Eng. Chem., 7, 56 (1915);<br></p>

<p>Applications DICHLOROTRIS(TRIPHENYLPHOSPHINE)RUTHENIUM(II) (cas# 15529-49-4) is a useful research chemical.<br></p>

<p>Applications Methyl α-bromophenylacetate is used in synthetic chemistry as an initiator for polymerization reactions (such as the polymerization of methyl methacrylate). Methyl α-bromophenylacetate is also used as a reagent to synthesize compounds that act as selective Serotonin (HCl: S274980) reuptake inhibitors (SSRI). SSRIs are used to modulate symptoms in autistic patients.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fors, B. &amp; Hawker, C.: Angew. Chem. Int. Edit., 51, 8850 (2012); Ghoneim, O., et al.: Bioorgan. Med. Chem. Lett., 21, 6714 (2011); O’Reilly, R., et al.: Macromolecules, 40, 7441 (2007)<br></p>

<p>Applications Potassium trimethylsilanolate is widely used in synthetic chemistry as a nucleophilic agent. Potassium Trimethylsilanolate is also used as a catalyst in the cyclization of diphenyldiaminosilane with organosilanes (such as dichlorophenylsilane).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andrianov, K., et al.: Chem. Hetero. Comp., 8, 679 (1972); Baker-Glenn, C., et al.: Tetrahedron Lett., 46, 7427 (2005); Jimonet, P., et al.: Bioorg. Med. Chem. Lett., 3, 983 (1993)<br></p>

<p>Applications 1,1,1-Trimethoxybutane is used in the synthesis of angiotensin II receptor antagonists affecting blood pressure. Also used in the preparation of inhibitors of cyclin-dependant kinases.<br>References Yanagisawa, H. et al.: J. Med. Chem., 39, 323 (1996);<br></p>

<p>Applications (R)​-​[2,​2'-​Bis(diphenylphosphin​o)​-​1,​1'-​binaphthyl]​dichlororuthenium is a catalyst used in the synthesis of helicobacter pylori lipopolysaccharide structures displaying anti-inflammatory activiy.<br>References Shimoyama, A. et al.: Chem. A Eur. J., 17, 14464 (2011);<br></p>

<p>Stability Moisture Sensitive<br>Applications N-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).<br>References Takano, R. et al.: J. Carb. Chem., 14, 885 (1995); Rao, K. et al.: Synth. Comm., 37, 2275 (2007);<br></p>

<p>Applications Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.<br>References Young, R.C., et al.: J. Med. Chem., 31, 670 (1988); Chai, B. et al.: Bioorg. Med. Chem. Lett., 23, 3505 (2013);<br></p>

<p>Applications (R)-Jorgensen-Hayashi Catalyst is a useful catalyst in enantioselective organic reactions.<br>References Bencivenni, G., et al.: Angew. Chem. Int. Ed., 48, 7200 (2009); Zhu, S., et al.: Angew. Chem. Int. Ed., 47, 545 (2008);<br></p>

<p>Stability Moisture Sensitive<br>Applications Aluminum Trichloride is a powerful chemical reagent used as a catalyst in Freidel Crafts reactions, alkylations and acylations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Groggins. P. et al.: Ind. Eng. Chem., 23, 152 (1931); Brown, H. et al.L J. Am. Chem. Soc., 80, 2291 (1958);<br></p>

<p>Applications 5,6,7,8-Tetrahydro-1-naphthylamine is used as a reagent in the synthesis of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels. 5,6,7,8-Tetrahydro-1-naphthylamine is also used as a reagent in the synthesis of benzopyrans and related compounds as inhibitors of the hypoxia inducible factor pathway.<br>References Roy, S., et al.: Eur. J. Med. Chem., 75, 426 (2014); Mooring, S.R., et al.: J. Med. Chem., 54, 8471 (2011)<br></p>

<p>Applications Iron(III) Bromide is used in the production of new disinfectant and in the study of it’s antimicrobial activity, improved synthesis of neotame, an artificial sweetner.<br>References Gluzman, M. K., et al.: Farmatsevtichnii Zhurnal, 24, 37 (1969); Yan, R., et al.: From Shipin Kexue (Beijing, China) (2008), 29(12), 312-315<br></p>