Glicoscienza

<p>Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside is a modification of the natural carbohydrate D-glucose and has been synthesized by methylation. This product has a purity of 99% and is made up of three monosaccharides: D-glucose, D-mannose, and D-galactose. It also contains an oligosaccharide chain that consists of 6 sugar units. Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside is insoluble in water but soluble in acetone. The molecular weight of this product is 522.2 g/mol.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>2,3-O-Isopropylidene-1-O-methyl-D-ribosic acid is a synthetic glycosylate that can be used to modify saccharides and oligosaccharides. It is a methylated form of ribose and has been shown to inhibit the glycosylation reactions of glycogen. 2,3-O-Isopropylidene-1-O-methyl-D-ribosic acid is also known to react with fluorine in order to produce a variety of fluorinated carbohydrates. This product has high purity and can be used for custom synthesis of carbohydrates. The CAS number for this product is 54622-95-6.</p>

<p>Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide, CAS No., Polysaccharide, Glycosylation, sugar, Carbohydrate</p>

<p>2-C-Hydroxymethyl- 2, 3:5, 6- di-O-isopropylidene-D-mannose is a synthetic monosaccharide. This compound has a fluorination and methylation step that causes the molecule to resemble a natural sugar. The addition of this modification allows for the synthesis of complex carbohydrates.</p>

<p>3-O-Benzyl 4-C-(methanesulfonyloxymethyl)-5-O-methanesulfonyl-1,2-O-isopropylidene-a-D-ribofuranose is an Oligosaccharide with a CAS number of 293751-01-6. It has been synthesized by Click modification and has a purity of greater than 98%. The glycosylation is custom synthesis. Glycosylations are modifications to saccharides that are added to the sugar chain in order to increase the biological activity or improve the pharmacokinetics of the drug.</p>

<p>2,3,5-Tri-O-acetyl-L-arabinofuranosyl fluoride is a monosaccharide sugar that has been fluorinated. It is a custom synthesis of methylation and click modification. The CAS number for this product is 565-64-8. This product has been modified to make it more resistant to degradation by enzymes such as alpha amylase and beta amylase. It is also used for polysaccharide synthesis and saccharides with higher purity than other products on the market. This product is synthesized from natural sources, making it high in purity and suitable for use in food production.END&gt;</p>

<p>4-O-Allyl-3,6-di-O-tert-butyldimethylsilyl-D-glucal is a custom synthesis of an oligosaccharide. It has been modified with fluorination, methylation, and click chemistry. 4-O-Allyl-3,6-di-O-tert-butyldimethylsilyl-D-glucal has been shown to be a high purity product that can be used in glycosylation reactions. This compound is very reactive and can be used in the synthesis of complex carbohydrates such as saccharides and polysaccharides.</p>

<p>Methyl 2,3,4-tri-O-benzyl-6-O-triisopropylsilyl-a-D-mannopyranoside is a glycosylation agent that can be used in the synthesis of oligosaccharides and polysaccharides. The compound is fluorinated at the C2 position and methylated at the C3 position. The final product is a white solid with a purity level of &gt;99%. The molecular formula is CHO and the molecular weight is 522.9 g/mol.<br>Methyl 2,3,4-tri-O-benzyl-6-O-(1,1'-biphenyl)-aD manno pyranoside can be synthesized through click chemistry by reacting an alkyne (1) with trimethylsilylacetylene (2). This reaction yields an α,β unsaturated carbonyl (3), which undergoes pall</p>

<p>L-iduronic acid (IdoA) (Collins, 2006) is the major uronic acid component of the glycosaminoglycans dermatan sulfate, chondroitin sulfate and heparin. Iduronic acid is also present in heparan sulfate, although in a minor amount relative to glucuronic acid. Glycosaminoglycans represent a physiologically important group of molecules involved in a variety of biological functions, such as, cell proliferation, cell-to-cell communication, wound healing, coagulation, morphogenesis, and pathogenesis. Glycosaminoglycans present an intriguing target for the design of new approaches for diagnostic and therapeutic agents against various infectious diseases (Kamhi, 2013).</p>

<p>Inhibitor and pharmacological chaperone of lysosomal β-glucosidase (glucosylceramidase). The compound binds to the unstable glucosidase active site during the folding and post-translational processing in Golgi apparatus and endoplasmatic reticulum. It is effective in stabilising the enzyme and preventing accumulation of glucosylceramides in models for Gaucher disease, especially in the ones carrying N370S mutation. In addition, it has antiviral activity against Hepatitis C virus, which is mediated by misfolding of viral glycoproteins in the presence of the inhibitor.</p>

<p>5-Azido-5,6-dideoxy-2,3-O-isopropylidene-D-gulonic acid-1,4-lactone is a carbohydrate that belongs to the group of saccharides. It is a synthetic sugar that has been modified with fluorine atoms on the 2 and 3 position of the sugar. 5-Azido-5,6-dideoxygulonic acid 1,4lactone has been shown to be resistant to enzymatic degradation by α amylase and β amylase. The compound also has a high level of purity (&gt;98%) and custom synthesis capabilities.</p>

<p>N-(Phenyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside (NPG) is a synthetic oligosaccharide. It is an Methylation and Click modification of the natural glycosylation product of glucose with pivalic acid. NPG has been shown to inhibit the Glycosylation enzyme by methylating it and preventing it to be able to catalyze the attachment of a sugar molecule to an amino acid residue. This inhibition prevents the production of complex carbohydrates in bacteria. NPG is also fluorinated at the 2,3,4,6 positions on the glucose ring which allows for better binding to bacterial cells. NPG has been shown to bind specifically to mycobacterial cell wall glycolipids and inhibit their synthesis as well as other bacterial cells such as staphylococcus aureus.</p>

<p>CO2-philic compound; used in pharmaceuticals and CO2-based processes</p>

<p>A3 Glycan, 2-AB labelled is a complex carbohydrate. It is synthesized by the methylation and glycosylation of the A3 sugar, which is a monosaccharide. The A3 Glycan, 2-AB labelled has a CAS No. of 711-81-2 and is a synthetic oligosaccharide with high purity. Its chemical formula is C6H8O5N2O2 and its molecular weight is 192.19 g/mol. The A3 Glycan, 2-AB labelled has an MW of 192.19 g/mol and an MW of 643 Da (1). It also contains one saccharide unit that consists of two bonded monosaccharides: fructose and glucose. A3 Glycan, 2-AB labelled CAS No.: 711-81-2 Molecular Formula: C6H8O5N2O2 Mole</p>

<p>2,4-Anhydro-3,5:6,7-di-O-isopropylidene-D-glycero-D-gulo-heptonic acid benzylamide is a glycosylation agent that is used in the synthesis of complex carbohydrate. It can be methylated and fluorinated to produce saccharides with desired properties. It also has a variety of chemical modifications for use as a synthetic sugar or oligosaccharide. 2,4-Anhydro-3,5:6,7-di-O-isopropylidene-D-glycero-D -gulo heptonic acid benzylamide is typically synthesized in high purity for use in pharmaceuticals or other applications requiring high purity.</p>

<p>Ethyl 2,4,6-tri-O-benzoyl-b-D-thiogalactopyranoside is a custom synthesis that is a modification of an oligosaccharide. It is a glycosylation and carbonylation product of an ethyl 2,4,6-tri-O-(benzoyl)-b-D-thioglucopyranoside. This product has been fluorinated and methylated. Ethyl 2,4,6-tri-O-(benzoyl)-b-D-thiogalactopyranoside is a polysaccharide with a complex carbohydrate structure. It has been modified by glycosylation and carbonylation.</p>

<p>Resource for the 6-O-modification of Glc e.g. in glucuronic acid synthesis</p>

<p>Building block for the synthesis of 2'-€‹C-€‹methyl substituted nucleosides</p>

<p>Low-calorie sweetener; additive in detergents, cosmetics, and pharmaceuticals</p>

<p>Raffinose is the most abundant of the family of oligosaccharides that are α-galactosyl derivatives of sucrose (Collins, 2006). The other main member of the group is the tetrasaccharide stachyose. Raffinose is found in sugar beet molasses and whole grains. Soybean oligosaccharides make up approximately 5% of dry matter in whole beans and up to 8% of dry matter in soybean meal. Together raffinose and stachyose rank second only to sucrose in abundance, as water-soluble carbohydrates (Kumar, 2010).</p>

<p>(2S, 3R, 4R) -3-Benzyloxy-1-butyl-4-(hydroxymethyl)-N-methyl-2-azetidinecarboxylic acid methyl ester is a modification of an oligosaccharide. This product is custom synthesized and has a high purity. It is a methylated carbohydrate that contains a fluorinated saccharide.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>The 1,2,3,4-Tetra-O-benzoyl-6-O-triisopropylsilyl-a-D-mannopyranose is a high purity custom synthesis sugar. It is a Click modification fluorination glycosylation synthetic mannose with methylation modification and CAS No.<br>Mannosaccharide is an oligosaccharide that consists of three monosaccharides linked by alpha (1-&gt;4) bonds. Monosaccharides are simple sugars containing either one or two sugar units. Carbohydrates are polymers of simple sugars and complex carbohydrates are polymers of more than ten sugars.</p>

<p>2-Butenoic acid methylester is a carbohydrate compound with a molecular formula of C4H6O4 and a molecular weight of 136.09. It has the chemical name of (2E) -4- [(3aS, 4R, 5aR) -5-hydroxy-( 2, 2-dimethyltetrahydro- 4H- 1, 3- dioxolo)[3, 4- c] piperidin- 2- yl] -2- butenoic acid meth yl ester. This product is an oligosaccharide that can be custom synthesized to meet your needs. This product is also known as an Oligosaccharide or sugar and can be fluorinated to produce a complex carbohydrate. The CAS number for this product is 72695-10-8. This product is available in high purity and has been methylated and glycosylated.</p>

<p>Gum karaya is exuded from Sterculia urens, a bushy tree found in dry regions of North India. Due to its extensive swelling capacity in water it is used as a laxative and as a denture adhesive. The structure consists of D-galactose, D-glucuronic acid and L-rhamnose but the detailed molecular structure is still incompletely known.</p>

<p>Methyl 2,3-di-O-acetyl-4,6-O-benzylidene-a-D-galactopyranoside is a custom synthesis of a complex carbohydrate that can be modified with a methyl group on the C2 position. This compound has been fluorinated and glycosylated in the laboratory. This product has high purity and is insoluble in water.</p>

<p>Biologically relevant in neurotransmission and carbohydrate-protein recognition</p>

<p>4,6-O-(4-Methoxybenzylidene)-1,2,3-tri-O-pivaloyl-a-D-mannopyranose is a sugar with the following characteristics: Glycosylation, complex carbohydrate, Methylation, Click modification, Polysaccharide, Fluorination and saccharide. The CAS No. of this compound is 44915-12-2. This compound can be synthesized to custom specifications or ordered as a stock chemical.</p>

<p>(2R, 3R, 4S, 5R) -3, 4- Dihydroxy- 5- (hydroxymethyl) - N- methyl-2- pyrrolidinecarboxami de is an Methylation product of 2-pyrrolidinone. It is a white to off-white solid. This product has been modified with Click chemistry to create a glycosylation site at the C6 position. It is soluble in water and alcohols. The CAS number for this product is 1591783-03-7.</p>

<p>2-Azido-2-deoxy-3,4-O-isopropylidene-L-lyxonic acid methyl ester is a custom synthesis, modification, fluorination and methylation of a monosaccharide. It is an Oligosaccharide and saccharide that is a complex carbohydrate.</p>

<p>2,3,5-Tri-O-benzyl-1,4-dideoxy-1,4-epithio-D-arabinitol is a compound that belongs to the family of thiosugars. It has been isolated from a variety of plant sources and has been shown to have inhibitory activity against the growth of bacteria. 2,3,5-Tri-O-benzyl-1,4-dideoxy-1,4 epithio D arabinitol inhibits bacterial growth by binding to the enzyme formate dehydrogenase and thereby prevents the formation of formate. This compound also inhibits salacinol and thiosugar synthesis in extracts of plants such as Salacia reticulata. 2,3,5 Tri O Benzyl 1,4 dideoxy 1 4 epithio D arabinitol is also found in the Ayurvedic medicine water extract known as voglibose.</p>

<p>Galactooligosaccharides (GOS) have a sweetness of 30–60 % relative to sucrose. They have applications in a wide range of food products such as sweeteners, bulking agents, and sugar substitutes and are found in a range of product types including bread, ‘sports’ drinks, jams, fermented milk, confectionary and desserts. In Europe they are incorporated into infant formula foods.</p>

<p>Methyl 5-Acetamido-N-benzyl-5,6-dideoxy-2,6-imino-3-O-benzyl-L-galactofuranoside is a modified carbohydrate with a methyl group at the C5 position. It is synthesized by modification of the saccharide and has a CAS number. This compound is used as a custom synthesis for synthesis of complex carbohydrates.</p>

<p>N-[(4'-Dimethylaminophenyl)-1-propenyl]imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranose is a fluorinated sugar that can be used for the synthesis of glycoconjugates. It is an oligosaccharide with an acetal linkage to the hydroxyl group at C2 and a pivaloyl group linked to the hydroxyl group at C3. This compound has been shown to be effective in methylation reactions.</p>

<p>L-Lyxonic acid potassium salt is a synthetic, fluorinated sugar that can be modified with a variety of functional groups. It is an excellent starting material for the synthesis of glycosylations, oligosaccharides, and sugar derivatives. L-Lyxonic acid potassium salt is typically used as a sugar substitute in food products. L-Lyxonic acid potassium salt is also used in the synthesis of complex carbohydrates and saccharides. L-Lyxonic acid potassium salt has been modified to include Click chemistry or other modifications to improve its properties.</p>

<p>(1R) -1- [(2S, 3S) - N-Methyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that is used in the manufacture of other chemical compounds. It has a CAS number of 93908-06-6 and can be custom synthesized to fit your needs. This product is highly pure and can be modified with methylation or glycosylation. The synthesis of this product can be done with click chemistry.</p>

<p>Methyl N-Benzyl-3-fluoro-2,3,4-trideoxy-2,4-imino-a-L-ribopyranoside is a fluorinated monosaccharide that is synthesized from an oligosaccharide. This compound is a glycosylation product of the natural polysaccharide maltose. It has been modified by methylation and click chemistry to produce a stable product with high purity.<br>Methyl N-Benzyl 3 Fluoro 2,3,4 Trideoxy 2,4 Imino A L Ribopyranoside has a molecular weight of 539.62 and is soluble in water at 25°C. It can be used as a sugar or carbohydrate for research purposes in laboratory settings.</p>

<p>(5R, 6S, 7R) -6, 7- Dihydro- 5- [(1R) - 1- hydroxyethyl] - 5H- pyrrolotetrazole- 6, 7- diol is a synthetic compound used in the synthesis of various complex carbohydrates. It is a methylated derivative of 2-(2-(4-nitrophenyl) diazenyl)-5H-pyrrolo[2,3-d]pyrimidine and can be synthesized by the click modification of an oligosaccharide or polysaccharide (such as cellulose). This compound has been modified with fluorine and is highly pure. It belongs to the group of monosaccharides and sugars.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>2-Acetamido-2,4-dideoxy-D-xylo-hexose is a synthetic monosaccharide that is modified with fluorine, methylation and acetamidodeoxysugar. The product is used as an intermediate in the synthesis of oligosaccharides and polysaccharides. It can also be used to modify saccharides with modifications such as click chemistry, fluorination and saccharide modification. 2-Acetamido-2,4-dideoxy-D-xylo-hexose (2A6DH) has CAS number 40555-55-3.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-galactopyranoside is a glycosylated sugar that can be custom synthesized or purchased. This product is a fluorinated oligosaccharide with a methyl group at C2. The chemical name for this modified sugar is O-(3,4,5,6-tetra-O-(1,1,1,3,3,3,-hexafluoroethoxy)propyl)-a-D-galactopyranose. It can be used in glycosylation reactions to modify the saccharides and it has an average purity of 99%. Methyl 2,3,4-tri-O-pivaloyl-6-O--triisopropylsilyl--a--D--galactopyranoside has a CAS</p>

<p>Synthetic building block for nucleic acid research</p>

<p>Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.   Purity typically above 60%.  Contains other oligosaccharide fragments.  For a typical IC trace see datasheet section</p>

<p>2-Hydroxydesipramine glucuronide is a metabolite of desipramine, which is a tricyclic antidepressant that inhibits the uptake of noradrenaline and 5-hydroxytryptamine. 2-Hydroxydesipramine glucuronide is formed by conjugation with glucuronic acid. It has been found in human urine and has been proposed as a biomarker for the clinical monitoring of patients taking desipramine. The pharmacological effects of 2-hydroxydesipramine glucuronide are similar to those of desipramine, but it is less potent and selective than its parent compound. This metabolite also has biliary excretion properties, which may be due to its small molecular size.</p>

<p>2,5-Anhydro-4-azido-4-deoxy-L-xylonic acid methyl ester is a custom synthesized carbohydrate that has been modified with glycosylation and methylation. This product can be used as a sugar or polysaccharide in the synthesis of complex carbohydrates. 2,5-Anhydro-4-azido-4-deoxy-L-xylonic acid methyl ester is an intermediate in the production of high purity monosaccharides for use in the manufacture of fluorinated saccharides.<br>2,5-Anhydro-4-azido-4-deoxy--L--xylonic acid methyl ester is also available from other suppliers.</p>

<p>The interaction of 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranoside with DNA is selective for the hydroxyl group and for the stacking of its glycosidic bonds. The data obtained from the spectra show that this compound interacts with the sugar moiety of nucleosides to yield a product with a lower melting point. The binding constants are high and the yields are low.</p>

<p>3-Deoxy-1,2-O-isopropylidene-5-O-toluoyl-b-L-ribofuranose is a sugar that is a methylated form of ribose. It also forms the backbone of polysaccharides and is modified with glycosylation. 3DOTRB can be custom synthesized in high purity and has CAS No. 2072145-19-6.</p>

<p>GT1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes. It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).</p>

<p>2-O-Acetamido-1,6-di-O-acetyl-2-deoxy-4-O-(2-acetamido-3,4,6-tri-O-acetyl)muramic acid is a synthetic oligosaccharide. This compound is used in research for the synthesis of glycosylides and glycosidase inhibitors. It can be modified to include fluorine atoms and click chemistry modifications. 2OAAmDDA is soluble in DMSO and acetone. It has a CAS number of 4891465.</p>