Nucleotidi
Sottocategorie di "Nucleotidi"
Trovati 2634 prodotti di "Nucleotidi"
Thymidine
CAS:Thymidine is a nucleoside that is found in cells and is involved in the synthesis of DNA. Thymidine has been shown to inhibit the growth of tumor cells through apoptosis. In addition, thymidine can be used for the treatment of bowel disease by reducing inflammation and increasing the production of mucin. The mechanism by which thymidine exerts its effects on tumor cells is not well understood, but it may involve interactions with dna binding activity and enzyme activities.
Formula:C10H14N2O5Purezza:Min. 99 Area-%Peso molecolare:242.23 g/molRef: 3D-Q-201829
1kgPrezzo su richiesta5kgPrezzo su richiesta250gPrezzo su richiesta500gPrezzo su richiesta2500gPrezzo su richiesta-Unit-kgkgPrezzo su richiesta2'-Deoxy-6-thioguanosine
CAS:2'-Deoxy-6-thioguanosine is a purine nucleoside analog that inhibits the activation of transcription factors such as nuclear factor kappa-B (NF-κB) and activator protein 1 (AP-1). It also inhibits the synthesis of proinflammatory cytokines, such as IL-1β, IL-6, and TNFα. The matrix effect is an important factor in the prevention of tumor progression. 2'-Deoxy-6-thioguanosine has been shown to inhibit cell proliferation and induce apoptosis in squamous cell carcinoma cells by modulating the expression of HLA class II molecules on tumors. It also prevents invasion by blocking matrix metalloproteinase activity. 2'-Deoxy-6-thioguanosine has been found to be effective against bowel diseases such as ulcerative colitis and Crohn's disease, as well as infectious diseases such as HIV/AIDS.Formula:C10H13N5O3SPurezza:Min. 97 Area-%Colore e forma:PowderPeso molecolare:283.31 g/mol5'-O-DMT-α-thymidine
5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.
Formula:C31H32N2O7Purezza:Min. 95%Peso molecolare:544.6 g/mol2'-Deoxy-L-cytidine
CAS:2'-Deoxy-L-cytidine is a nucleoside that is naturally found in the cells of E. coli K-12. It is an antioxidant compound that prevents lipid peroxidation and scavenges free radicals, which are generated by certain chemical reactions. 2'-Deoxy-L-cytidine has been shown to have antiviral potency in vitro, but its antiviral activity has not been evaluated in vivo. This compound also inhibits the growth of bacteria that are resistant to tetracycline, such as Mycobacterium tuberculosis and Helicobacter pylori. 2'-Deoxy-L-cytidine may cause drug interactions with other medications because it is metabolized by the CYP450 system and inhibits the activity of cytochrome P450 enzymes.
Formula:C9H13N3O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:227.22 g/mol8-Oxoguanosine
CAS:8-Oxoguanosine is an oxidative DNA lesion that has been shown to be a potential biomarker for the detection of cancer cells. 8-Oxoguanosine is produced by a number of pharmacological agents and reactive oxygen species, such as hydrogen peroxide and nitric oxide. It has been shown to bind to DNA duplexes, inhibiting their replication and repair, which may lead to cancer development. The electrochemical detector can detect 8-oxoguanosine at concentrations as low as 1 μM in biological samples.Formula:C10H13N5O6Purezza:Min. 98 Area-%Colore e forma:White Off-White PowderPeso molecolare:299.24 g/mol3'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a nucleic acid that is involved in the synthesis of polysaccharides and proteins. It has been shown to have an inhibitory effect on the synthesis of collagen, which may be due to its ability to increase hydrogen bonding between the nitrogen atoms and oxygen atoms. 3'-Deoxyguanosine has also been shown to have a protective effect on wheat germ extract, which may be due to its ability to inhibit oxidation reactions. The chemical structure of 3'-deoxyguanosine can be synthesized by reacting deoxyribose with sodium nitrate in the presence of sulfuric acid. This reaction can be monitored using electrochemical impedance spectroscopy (EIS).Formula:C10H13N5O4Purezza:Min. 95%Colore e forma:White Off-White PowderPeso molecolare:267.25 g/mol2'-Deoxy-5-fluorocytidine
CAS:2'-Deoxy-5-fluorocytidine is a methyltransferase inhibitor that inhibits the activity of DNA methyltransferases. It has been shown to inhibit the activity of DNA methyltransferases in vitro and in vivo, leading to tumor cell death. 2'-Deoxy-5-fluorocytidine has been shown to target intracellular targets, such as histones and ribosomes, which are involved in cancer development. The toxicity of this drug has been studied extensively and it has been shown to have low toxicity in mice. This drug is not toxic for normal cells or animals when administered at high doses.
Formula:C9H12FN3O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:245.21 g/mol2',3',5'-Tri-O-acetyl-5-bromouridine
CAS:2',3',5'-Tri-O-acetyl-5-bromouridine is a nucleoside analog of uridine, a basic building block of RNA. It has the addition of a bromine atom and three acetyl groups. 2',3',5'-Tri-O-acetyl-5-bromouridine can be used in researchFormula:C15H17BrN2O9Purezza:Min. 90%Peso molecolare:449.21 g/mol2'-Deoxy-5'-O-DMT-inosine
CAS:2'-Deoxy-5'-O-DMT-inosine is a chain congener of uridine and cytidine. It is an analog of guanosine, which is found in DNA. 2'-Deoxy-5'-O-DMT-inosine has shown to have cytotoxic effects on the cardiovascular system, as well as inflammatory properties. This drug can also inhibit nitric oxide production and chloride transport. The nitro group in 2'-deoxy-5'-O-DMT-inosine can be removed by ammonolysis or debenzoylation and glycosylation can be added to the molecule with the addition of glucose.Formula:C31H30N4O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:554.61 g/mol2-Amino-2'-O-methyladenosine
CAS:2-Amino-2'-O-methyladenosine is a modified nucleoside based on adenosine with a 2-amino group on the base, and a 2'-O-methyl group on the sugar.
Formula:C11H16N6O4Purezza:Min. 97 Area-%Colore e forma:White PowderPeso molecolare:296.28 g/mol(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine
CAS:(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine is a nucleoside for a range of applicationsFormula:C12H14N2O7Purezza:Min. 97 Area-%Colore e forma:White PowderPeso molecolare:298.25 g/molGuanosine 2',3'-cyclic monophosphate sodium
CAS:Guanosine 2',3'-cyclic monophosphate sodium is a novel antiviral agent that has been shown to be effective against HIV, herpesviruses, and vaccinia virus. It is an activator of guanosine 3'-5' cyclic monophosphate (cGMP) and can be used as a substitute for the nucleoside guanosine 5'-triphosphate (GTP). Guanosine 2',3'-cyclic monophosphate sodium inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase and DNA polymerase. This drug also has anticancer properties, which may be due to its ability to inhibit the production of tumor necrosis factor-α (TNF-α) in mice with lung cancer.Formula:C10H11N5NaO7PPurezza:Min. 97 Area-%Colore e forma:PowderPeso molecolare:367.19 g/molAdenosine 5'-diphosphate
CAS:Adenosine 5'-diphosphate (ADP) is a nucleoside that is an important component of the cell's energy pathways. ADP plays a role in platelet activation and nitrate reductase, which are enzymes that maintain the integrity of bacterial DNA. Adenosine 5'-diphosphate also has been shown to inhibit neural cell injury and protein oxidation.
Formula:C10H15N5O10P2Purezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:427.2 g/mol8-Bromo-2'-deoxyadenosine
CAS:8-Bromo-2'-deoxyadenosine (8-BrdA) is a reactive chemical that can be used in the study of DNA. It is used to measure the kinetics of oxidative dna damage and to study glycosidic bond cleavage reactions. 8-BrdA reacts with eosinophil peroxidase to yield an oxidant, which can then react with dna duplexes. This reaction has been shown to affect both intramolecular and intermolecular hydrogen bonds. 8-BrdA also has been shown to induce cell death in vitro by apoptosis.Formula:C10H12BrN5O3Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:330.14 g/mol3'-Deoxy-3'-fluorothymidine
CAS:3'-Deoxy-3'-fluorothymidine is a nucleoside analog that is used to diagnose and treat cancer. It is a prodrug that is metabolized intracellularly by deoxycytidine kinase to the 3'-deoxy-3'-fluoro derivative of thymidine, which competes with natural thymidine for incorporation into DNA. Uptake of 18F-flouride (18F-FDG) in tumor cells has been shown to be proportional to the rate constant (k) of cellular uptake. This process can be quantified using positron emission tomography imaging. The cell cycle inhibitor activity of 3'-deoxy-3'-fluorothymidine has also been demonstrated in vitro and in vivo, inhibiting the proliferation of tumor cells and normal cells in culture, respectively.Formula:C10H13FN2O4Purezza:Min. 97 Area-%Colore e forma:White Off-White PowderPeso molecolare:244.22 g/mol5-Chloro-2-pyridinecarboxylic acid methyl ester
CAS:5-Chloro-2-pyridinecarboxylic acid methyl ester is a monophosphate nucleoside that can be used in the synthesis of DNA and RNA. It is also an antiviral, anticancer, and anticoagulant agent. 5-Chloro-2-pyridinecarboxylic acid methyl ester has been shown to inhibit DNA replication and transcription by inhibiting the activity of enzymes involved in these processes. It can be used as a building block for the synthesis of DNA and RNA. The purity of this product is high, with no detectable impurities at levels above 0.1%.Formula:C7H6ClNO2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:171.58 g/molGuanylyl-3'-5'-cytidine ammonium salt
CAS:Guanylyl-3'-5'-cytidine ammonium salt is a nucleoside that is classified as a diphosphate. It has high quality and novel, anticancer and cytotoxic effects. Guanylyl-3'-5'-cytidine ammonium salt is synthesized from guanosine monophosphate (GMP) and cytidine monophosphate (CMP).Formula:C19H25N8O12P·NH3Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:605.46 g/mol9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine
CAS:9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine is a synthetic nucleoside that can be phosphorylated to form 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine 5'-triphosphate. This compound has been shown to have antitumor and antiviral activities. It inhibits DNA synthesis by inhibiting the activity of DNA polymerase and RNA polymerase, which are enzymes necessary for the replication of cellular DNA and RNA, respectively. 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine is high quality, novel, and CAS No. 98983-40-5.Formula:C10H11FN4O4Purezza:Min. 95%Colore e forma:White Off-White PowderPeso molecolare:270.22 g/molIsocytidine
CAS:Isocytidine, also known as 2-amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone, have broad antitumor activity targeting indolent lymphoid malignancies.
Formula:C9H13N3O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:243.22 g/molN7-Methylguanosine
CAS:N-7-Methylguanosine is a nucleotide that has potent anti-viral activity. It inhibits viral replication by binding to the effector proteins of a virus and preventing translation, transcriptional regulation, and other biochemical processes. N7-Methylguanosine also binds to the x-ray crystal structures of the viral genome and blocks the binding of RNA polymerase to DNA. This drug can be used as an antiviral agent for the treatment of HIV infection and hepatitis B infection. N7-Methylguanosine is not active against some viruses such as herpes simplex virus type 1 or 2, influenza virus type A/B, or rhinovirus type 2. N7-Methylguanosine has been shown to have an effect on body mass index in humans by reducing weight gain in patients with metabolic syndrome. It also has an enzyme form that can be used for therapeutic use in human serum.Formula:C11H15N5O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:297.27 g/mol
