Inibitori
Gli inibitori sono molecole che si legano a enzimi, recettori o altre proteine per ridurre o bloccare la loro attività biologica. Questi composti sono ampiamente utilizzati nella ricerca per studiare le vie biologiche, comprendere i meccanismi delle malattie e sviluppare farmaci terapeutici. Gli inibitori svolgono un ruolo cruciale nel trattamento di varie malattie, tra cui il cancro, le malattie cardiovascolari e le infezioni. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità per supportare le tue ricerche in biochimica, biologia cellulare e sviluppo farmaceutico.
Sottocategorie di "Inibitori"
- Angiogenesi(2.811 prodotti)
- Apoptosi(6.295 prodotti)
- Ciclo cellulare/Checkpoint(4.842 prodotti)
- Cromatina/Epigenetica(2.526 prodotti)
- Segnalazione citoscheletrica(1.550 prodotti)
- Danno al DNA/Riparazione del DNA(2.917 prodotti)
- Endocrinologia/Ormoni(3.708 prodotti)
- Enzima(3.671 prodotti)
- Proteina G/GPCR(9.024 prodotti)
- Immunologia e infiammazione(3.896 prodotti)
- Virus dell'influenza(302 prodotti)
- Segnalazione JAK/STAT(418 prodotti)
- Segnalazione MAPK(1.248 prodotti)
- Trasportatore di membrana/canale ionico(3.094 prodotti)
- Metabolismo(10.157 prodotti)
- Microbiologia/Virologia(7.623 prodotti)
- Neuroscienza(10.360 prodotti)
- Altri inibitori(35.913 prodotti)
- Ossidazione-riduzione(40 prodotti)
- Segnalazione PI3K/Akt/mTOR(1.440 prodotti)
- Proteasi/Proteasoma(1.711 prodotti)
- Cellule staminali e Derivati(792 prodotti)
- Adattatori Tirosin-chinasi(2.013 prodotti)
- Ubiquitinazione(1.722 prodotti)
Mostrare 16 più sottocategorie
Trovati 66619 prodotti di "Inibitori"
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Laulimalide
CAS:Microtubule stabilizer; halts cancer cell growth (IC50: 3-30 nM); arrests cells in prometaphase; prevents bipolar spindle formation.Formula:C30H42O7Colore e forma:SolidPeso molecolare:514.65Antitumor agent-77
Antitumor agent-77 suppresses cancer cell growth, migration, induces apoptosis, and hinders EMT.Formula:C7H11F3N2O5PtColore e forma:SolidPeso molecolare:455.25Glutaminyl Cyclase Inhibitor 3
CAS:Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formula:C24H32N6O2SPurezza:98%Colore e forma:SolidPeso molecolare:468.61VEGFR-2-IN-25
CAS:VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 (IC50: 12.1 nM).Formula:C24H22N6O2Colore e forma:SolidPeso molecolare:426.47UAWJ9-36-1
CAS:UAWJ9-36-1: potent broad-spectrum coronavirus Protease inhibitor; IC50 = 51 nM.Formula:C23H29N3O5Colore e forma:SolidPeso molecolare:427.49MsbA-IN-5
MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.Formula:C23H19Cl2N5OColore e forma:SolidPeso molecolare:452.34Dexnebivolol
CAS:Dexnebivolol (R67138), a ß-adrenergic antagonist, is Nebivolol's enantiomer with β1 blocking and vasodilation properties.Formula:C22H25F2NO4Colore e forma:SolidPeso molecolare:405.43Cryptopleurine
CAS:Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.Formula:C24H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:377.48XY153
XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.Formula:C33H34FN3O4Colore e forma:SolidPeso molecolare:555.64SOS1-IN-9
SOS1-IN-9 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 116.5 nM).Formula:C22H28F3N5OColore e forma:SolidPeso molecolare:435.49HDAC1-IN-3
HDAC1-IN-3 is a potent inhibitor of Pf HDAC1.Formula:C22H24ClN7O2Colore e forma:SolidPeso molecolare:453.92HIF-2α-IN-7
CAS:HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor.Formula:C18H9F6NO2Colore e forma:SolidPeso molecolare:385.26CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Formula:C18H18F2N4SColore e forma:SolidPeso molecolare:360.42COX-2-IN-9
COX-2-IN-9: potent oral COX-2 blocker, selective over Celecoxib, IC50 10.17 μM, less ulcers, strong anti-inflammatory.Formula:C25H23N5O4S2Colore e forma:SolidPeso molecolare:521.611,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formula:C22H34O5Purezza:98%Colore e forma:SolidPeso molecolare:378.5Cortistatin A
CAS:Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.Formula:C30H36N2O3Purezza:98%Colore e forma:SolidPeso molecolare:472.62Tasidotin hydrochloride
CAS:Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.Formula:C32H59ClN6O5Purezza:98%Colore e forma:SolidPeso molecolare:643.30Flusoxolol
CAS:Flusoxolol is a beta-adrenoceptor partial agonist.Formula:C22H30FNO4Colore e forma:SolidPeso molecolare:391.48PDE4-IN-14
CAS:PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, includingFormula:C19H20F2N4O3SColore e forma:SolidPeso molecolare:422.45CDK4/6-IN-13
CAS:Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.Formula:C25H29N7OColore e forma:SolidPeso molecolare:443.54AMG-25
CAS:AMG-25 (c-Kit-IN-5-1) is a c-Kit inhibitor that inhibits c-Kit, KDR, p38, Lck, and Src, and can be used for the study of mast cell-associated fibrotic diseases.Formula:C23H17N5O2Purezza:98.16%Colore e forma:SolidPeso molecolare:395.41PM-060184
CAS:PM-060184, a tubulin polymerisation inhibitor, is used potentially for the treatment of solid tumours and breast cancer.Formula:C31H45N3O7Purezza:98%Colore e forma:SolidPeso molecolare:571.7AZD-4121
CAS:AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.
Formula:C36H39F2N3O7SColore e forma:SolidPeso molecolare:695.77Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Formula:C29H42Cl2FN3O4Colore e forma:SolidPeso molecolare:586.57APN/AKT-IN-1
APN/AKT-IN-1, a dual APN (IC50=0.21μM) & AKT (IC50=0.27μM) inhibitor, hinders GSK3β phosphorylation.Formula:C18H27N7O3Colore e forma:SolidPeso molecolare:389.45NS2B/NS3-IN-3
CAS:NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .Formula:C19H21N3O2Colore e forma:SolidPeso molecolare:323.39PKG1α activator 3
PKG1α activator 3 is a PKG1α activator (EC50basal/partial=13/0.52 μM).Formula:C27H26Cl2N2O6Colore e forma:SolidPeso molecolare:545.41T-2513 hydrochloride
CAS:T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.Formula:C25H28ClN3O5Colore e forma:SolidPeso molecolare:485.96Esorubicin
CAS:Esorubicin, a doxorubicin derivative, intercalates DNA, inhibits topoisomerase II, has less cardiotoxicity, but more myelosuppression.Formula:C27H29NO10Colore e forma:SolidPeso molecolare:527.52FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Colore e forma:SolidSLN124
SLN124, a GalNAc-siRNA targeting TMPRSS6, may normalize iron balance by restoring ferroregulation.Colore e forma:SolidCLR01 sodium
CAS:CLR01 is a tweezer reducing α-synuclein in MSA, inhibits SOD1 in ALS, blocks Ebola/Zika, stabilizes proteins, and lessens mutant p53 toxicity.Formula:C42H30Na2O8P2Colore e forma:SolidPeso molecolare:770.6211(+)-Cevimeline hydrochloride hemihydrate
(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.Formula:C10H19ClNO1·5SPurezza:98%Colore e forma:SolidPeso molecolare:244.78L 365209
CAS:L 365209 is an oxytocin antagonist.Formula:C40H50N8O6Purezza:98%Colore e forma:SolidPeso molecolare:738.88Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formula:C31H39N5O7Purezza:98%Colore e forma:SolidPeso molecolare:593.67Tezampanel hydrate
CAS:Tezampanel is used for the treatment of migraine, neuropathic pain.Formula:C13H23N5O3Colore e forma:SolidPeso molecolare:297.35GLS1 Inhibitor-5
GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.Colore e forma:SolidDS01080522
DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.Formula:C23H20Cl2N4O3Colore e forma:SolidPeso molecolare:471.34HP590
CAS:HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formula:C29H24F6N4O3Colore e forma:SolidPeso molecolare:590.52264W94
CAS:264W94 robustly inhibits IBAT, induces CYP7A1, and significantly reduces cholesterol.Formula:C23H31NO4SPurezza:98%Colore e forma:SolidPeso molecolare:417.56Bometolol Hydrochloride
CAS:Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.Formula:C25H33ClN2O7Purezza:98%Colore e forma:SolidPeso molecolare:508.99MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formula:C23H24ClN3O3Colore e forma:SolidPeso molecolare:425.91(R)-ONO-2952
(R)-ONO-2952 is the R-enantiomer of ONO-2952. ONO-2952 is selective and oral effective TSPO antagonist, with Kis of 0.330-9.30 nM inhibiting rat and human TSPO.Formula:C22H20ClFN2O2Colore e forma:SolidPeso molecolare:398.86α-Amylase-IN-1
CAS:α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM).Formula:C18H18N2O3Purezza:99.92%Colore e forma:SoildPeso molecolare:310.35TAP311
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).Formula:C34H40F6N6O4Purezza:98%Colore e forma:SolidPeso molecolare:710.71PD 113271
CAS:PD 113,271 is an analog of the fermentation products fostriecin with antitumor activity in vitro and in vivo.Formula:C19H27O10PPurezza:98%Colore e forma:SolidPeso molecolare:446.39PDHK-IN-3
PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].Formula:C17H16N2O2Colore e forma:SolidPeso molecolare:280.32Desacetylravidomycin
CAS:Desacetylravidomycin is a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326.Formula:C29H31NO8Colore e forma:SolidPeso molecolare:521.56Tubulin inhibitor 22
Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.Formula:C20H17BrFNO4Colore e forma:SolidPeso molecolare:434.26Amicoumacin A
CAS:Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.Formula:C20H29N3O7Purezza:98%Colore e forma:SolidPeso molecolare:423.46MF-592
CAS:MF-592: EP4 receptor antagonist, hEP4 IC50 3 nM, hWB IC50 78 nM, great oral PK, rat arthritis ED50 0.1 mg/kg/day, promising for development.Formula:C34H33Cl2N3O6SColore e forma:SolidPeso molecolare:682.61Carbonic anhydrase inhibitor 2
CAS:Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.Formula:C12H16N4O6SColore e forma:SolidPeso molecolare:344.34LY 215840
CAS:5-HT2/5-HT7 receptor antagonistFormula:C24H33N3O2Purezza:98%Colore e forma:SolidPeso molecolare:395.54SOS1-IN-6
CAS:SOS1-IN-6 (compound 33-P1) is a potent inhibitor of SOS1, acting on SOS1-G12D (IC50: 14.9 nM) and SOS1-G12V (IC50: 73.3 nM).Formula:C26H28F3N3O2Colore e forma:SolidPeso molecolare:471.51Terguride
CAS:Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.Formula:C20H28N4OColore e forma:SolidPeso molecolare:340.46Beclabuvir
CAS:Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.Formula:C36H45N5O5SPurezza:99.87% - 99.93%Colore e forma:SolidPeso molecolare:659.84SML-10-70-1
CAS:SML-10-70-1 is a Novel Active Site Inhibitor of Oncogenic K-Ras G12C.Formula:C25H42ClN7O13P2Colore e forma:SolidPeso molecolare:746.04(S)-Butaprost free acid
CAS:(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].Formula:C23H38O5Colore e forma:SolidPeso molecolare:394.54BAY-899
CAS:BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.Formula:C25H19F2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:459.45Anti-inflammatory agent 13
Pentacyclic triterpene, Anti-inflammatory 13 inhibits DAMP/PAMP inflammation models.Formula:C30H48O4Colore e forma:SolidPeso molecolare:472.7AChE-IN-8
AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.Formula:C20H22N4O2SColore e forma:SolidPeso molecolare:382.48L-697639
CAS:L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.Formula:C18H21N3O2Colore e forma:SolidPeso molecolare:311.38PI3K-IN-29
CAS:PI3K-IN-29: Strong PI3K block, inhibits Akt phosphorylation. IC50: U87MG 0.264µM, HeLa 2.04µM, HL60 1.14µM.Formula:C27H22ClN7O3SColore e forma:SolidPeso molecolare:560.03Chitinase-IN-4
Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.Formula:C21H24ClN7Colore e forma:SolidPeso molecolare:409.92Vulolisib
CAS:Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.Formula:C18H19F2N5O3SColore e forma:SolidPeso molecolare:423.44Lp-PLA2-IN-10
Lp-PLA2-IN-10, a potent Lp-PLA2 inhibitor, may research neurodegenerative and cardiovascular diseases.Formula:C21H15F5N4O4Colore e forma:SolidPeso molecolare:482.36D1R antagonist 1
CAS:Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formula:C22H26BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:448.35Numidargistat
CAS:CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).Formula:C11H22BN3O5Purezza:98%Colore e forma:SolidPeso molecolare:287.12A1AR antagonist 1
Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).Formula:C18H14N4OColore e forma:SolidPeso molecolare:302.33Keap1-Nrf2-IN-1 TFA
Keap1-Nrf2-IN-1 TFA (compound35) is a potent inhibitor (IC50: 43 nM) protecting against acetaminophen liver damage.Formula:C26H25F3N2O9SColore e forma:SolidPeso molecolare:598.54BXL0124
CAS:BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.Formula:C32H44F6O4Colore e forma:SolidPeso molecolare:606.68Coleon-U-quinone
CAS:Coleon-U-quinone, a P-gp inhibitor, reduces cancer cell viability and enhances Doxorubicin sensitivity in resistant cells.Formula:C20H24O5Colore e forma:SolidPeso molecolare:344.4TT15
CAS:TT15 is an agonist of the GLP-1R.Formula:C51H44Cl2N4O6Colore e forma:SolidPeso molecolare:879.8217β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.Formula:C21H21NO3Colore e forma:SolidPeso molecolare:335.4(Rac)-BI 703704
CAS:(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).Formula:C32H37N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:559.72ERK-IN-2
CAS:ERK-IN-2, an ERK2 inhibitor, exhibits an IC50 value of 1.8 nM. At doses greater than 10 μM, it may induce off-target toxicity and/or activity [1].Formula:C16H18ClN5O2Purezza:98%Colore e forma:SolidPeso molecolare:347.80PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Formula:C22H29N5O2Colore e forma:SolidPeso molecolare:395.5(2S,3R)-LP99
CAS:(2S,3R)-LP99 is a less active enantiomer of LP99.Formula:C26H30ClN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:516.05Ro 31-8472
CAS:Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.Formula:C20H27N3O6Purezza:98%Colore e forma:SolidPeso molecolare:405.44Pareptide monohydrochloride
CAS:Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).Formula:C14H27ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:334.84Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Formula:C14H7Cl2F3N2OColore e forma:SolidPeso molecolare:347.12Antibacterial agent 80
Antibacterial agent 80 (compound 20) has antibacterial activity [1].Formula:C14H21N3S2Colore e forma:SolidPeso molecolare:295.47F 14679
CAS:F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.
Formula:C21H25ClF2N4OPurezza:99.09%Colore e forma:SolidPeso molecolare:422.9Aquayamycin
CAS:Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Formula:C25H26O10Colore e forma:SolidPeso molecolare:486.47MraY-IN-1
MraY-IN-1 inhibits MraY (IC50: 140μM), fights E. coli K12, B. subtilis W23, P. fluorescens (MIC50: 7-46μg/ml), for antimicrobial research.Formula:C35H46N3O5Colore e forma:SolidPeso molecolare:588.76PDE-I2
CAS:PDE-I2 is a parasite schizogony inhibitor.Formula:C25H23N5O8Colore e forma:SolidPeso molecolare:521.48OXS007417
OXS007417 induces AML cell differentiation at 48 nM EC50 and shows potent in vivo antitumor effects.Formula:C20H14F3N3OColore e forma:SolidPeso molecolare:369.34IRAK4-IN-11
IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].Formula:C16H19N7OColore e forma:SolidPeso molecolare:325.37M3258
CAS:LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer, is an inhibitor ofFormula:C17H20BNO5Purezza:98%Colore e forma:SolidPeso molecolare:329.16PRN694
CAS:PRN694 is a potent, irreversible ITK/RLK inhibitor with IC50s: 0.3/1.4 nM; offers lasting effector cell suppression.Formula:C28H35F2N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:543.67SARS-CoV-2-IN-24
SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.Formula:C27H30N4O5Colore e forma:SolidPeso molecolare:490.55Lorajmine
CAS:Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.Formula:C22H27ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:402.91Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Formula:C16H25N7O8Colore e forma:SolidPeso molecolare:443.41FPR2 agonist 2
Potent FPR2 agonist, crosses blood-brain barrier, EC50: 0.13 nM; reduces inflammation and mitochondrial dysfunction, inhibits caspase-3.Formula:C25H20F2N4O2Colore e forma:SolidPeso molecolare:446.45(Rac)-Plevitrexed
CAS:(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).Formula:C26H25FN8O4Purezza:98%Colore e forma:SolidPeso molecolare:532.53EGFR-IN-23
CAS:EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.Formula:C36H44BrN10O3PColore e forma:SolidPeso molecolare:775.68EGFR-IN-45
EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.Formula:C28H23N7OColore e forma:SolidPeso molecolare:473.53ATP synthase inhibitor 2
CAS:ATP synthase inhibitor 2 blocks P. aeruginosa ATP synthase; IC50=10 μg/mL, fully inhibits at 128 μg/mL.Formula:C21H22N2O3SColore e forma:SolidPeso molecolare:382.48Taranabant
CAS:Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.Formula:C27H25ClF3N3O2Purezza:99.06% - 99.06%Colore e forma:SolidPeso molecolare:515.96Anticancer agent 143
CAS:Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM.Formula:C19H15BrF2N3O6PS2Purezza:98%Colore e forma:SolidPeso molecolare:594.34
