Inibitori
Gli inibitori sono molecole che si legano a enzimi, recettori o altre proteine per ridurre o bloccare la loro attività biologica. Questi composti sono ampiamente utilizzati nella ricerca per studiare le vie biologiche, comprendere i meccanismi delle malattie e sviluppare farmaci terapeutici. Gli inibitori svolgono un ruolo cruciale nel trattamento di varie malattie, tra cui il cancro, le malattie cardiovascolari e le infezioni. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità per supportare le tue ricerche in biochimica, biologia cellulare e sviluppo farmaceutico.
Sottocategorie di "Inibitori"
- Angiogenesi(2.797 prodotti)
- Apoptosi(6.275 prodotti)
- Ciclo cellulare/Checkpoint(4.805 prodotti)
- Cromatina/Epigenetica(2.462 prodotti)
- Segnalazione citoscheletrica(1.534 prodotti)
- Danno al DNA/Riparazione del DNA(2.959 prodotti)
- Endocrinologia/Ormoni(3.708 prodotti)
- Enzima(3.670 prodotti)
- Proteina G/GPCR(9.020 prodotti)
- Immunologia e infiammazione(3.884 prodotti)
- Virus dell'influenza(301 prodotti)
- Segnalazione JAK/STAT(414 prodotti)
- Segnalazione MAPK(1.249 prodotti)
- Trasportatore di membrana/canale ionico(3.050 prodotti)
- Metabolismo(10.206 prodotti)
- Microbiologia/Virologia(7.612 prodotti)
- Neuroscienza(10.379 prodotti)
- Altri inibitori(36.012 prodotti)
- Ossidazione-riduzione(42 prodotti)
- Segnalazione PI3K/Akt/mTOR(1.442 prodotti)
- Proteasi/Proteasoma(1.724 prodotti)
- Cellule staminali e Derivati(819 prodotti)
- Adattatori Tirosin-chinasi(2.035 prodotti)
- Ubiquitinazione(1.718 prodotti)
Mostrare 16 più sottocategorie
Trovati 66683 prodotti di "Inibitori"
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Lisuride
CAS:Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Formula:C20H26N4OColore e forma:SolidPeso molecolare:338.45KMN-80
CAS:KMN-80 is a potent, selective EP4 agonist with IC50 3 nM, spurring osteoblast differentiation, and showing in vivo bone repair efficacy.Formula:C21H33NO4Colore e forma:SolidPeso molecolare:363.49Hoe 892
CAS:Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.Formula:C20H33NO4SColore e forma:SolidPeso molecolare:383.55PD-1-IN-17 TFA
PD-1-IN-17 TFA is a potent PD-1 inhibitor, blocking 92% of splenocyte growth at 100 nM.Formula:C15H23F3N6O9Colore e forma:SolidPeso molecolare:488.37PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formula:C33H33N3O4Colore e forma:SolidPeso molecolare:535.63MDK-3298
CAS:MDK-3298 is a reversible covalent inhibitor of Mcl-1, a target of protein-protein interaction (PPI).Formula:C35H32BN3O7Purezza:98%Colore e forma:SolidPeso molecolare:617.46CARM1-IN-3 dihydrochloride
CARM1-IN-3 dihydrochloride (17b) is a potent CARM1 inhibitor (IC50: 0.07 μM) with selectivity over CARM3 (IC50 >25 μM).Formula:C24H34Cl2N4O2Colore e forma:SolidPeso molecolare:481.46MC2652
MC2652, a potent LSD1 inhibitor, suppresses leukemia (MV4-11, NB4) and impedes prostate cancer (LNCaP) cell growth.Formula:C22H20N2OColore e forma:SolidPeso molecolare:328.41Acetoxycycloheximide
CAS:<p>Acetoxycycloheximide triggers TNF receptor 1, prompts apoptosis, and cytochrome c release by activating c-Jun N-terminal kinase.</p>Formula:C17H25NO6Colore e forma:SolidPeso molecolare:339.38FAPI-74
CAS:<p>FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.</p>Formula:C36H49N9O8Colore e forma:SolidPeso molecolare:735.83DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Formula:C32H33Cl2FN4O3Colore e forma:SolidPeso molecolare:611.53COX-2-IN-8
COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.Formula:C19H19N3O4S2Colore e forma:SolidPeso molecolare:417.5Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Formula:C29H42Cl2FN3O4Colore e forma:SolidPeso molecolare:586.57EP4 receptor antagonist 2
CAS:EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.Formula:C27H29N3O5Colore e forma:SolidPeso molecolare:475.54Dinordrin
CAS:Dinordrin is an implantation inhibitor and hormone.Formula:C27H36O4Purezza:98%Colore e forma:SolidPeso molecolare:424.57GDC-0927 Racemate
CAS:GDC-0927 Racemate is a degrader of estrogen receptor, is used in the research of ER-related diseases, potently inhibits ER-α activity, with an IC50 of 0.2 nM.Formula:C28H28FNO4Purezza:98%Colore e forma:SolidPeso molecolare:461.52Vulolisib
CAS:Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.Formula:C18H19F2N5O3SColore e forma:SolidPeso molecolare:423.44PD 135158
CAS:PD 135158 is a CCK2 receptor antagonist.Formula:C42H61N5O11Purezza:98%Colore e forma:SolidPeso molecolare:811.96Novokinin
CAS:Angiotensin AT2 receptor agonistFormula:C39H61N11O7Purezza:98%Colore e forma:SolidPeso molecolare:795.97PD 113271
CAS:PD 113,271 is an analog of the fermentation products fostriecin with antitumor activity in vitro and in vivo.Formula:C19H27O10PPurezza:98%Colore e forma:SolidPeso molecolare:446.39EGFR-IN-3
EGFR-IN-3 is an EGFR inhibitor with antitumor activity.EGFR-IN-3 inhibits EGFRwt-TK, induces apoptosis (cell death), and can block cells in the G2/M phase.Formula:C24H18F4N6O2SPurezza:98.1%Colore e forma:SolidPeso molecolare:530.5AKR1C3-IN-8
AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.Formula:C23H20N4O3Colore e forma:SolidPeso molecolare:400.43Mal-PEG4-VA-PBD
CAS:Mal-PEG4-VA-PBD is a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), comprising the antitumor antibiotic Pyrrolobenzodiazepine (PBD), connectedFormula:C68H79N9O17Purezza:98%Colore e forma:SolidPeso molecolare:1294.41Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Formula:C16H22ClNOSColore e forma:SolidPeso molecolare:311.87CBP/p300-IN-18
CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).Formula:C25H27FN4O3Colore e forma:SolidPeso molecolare:450.51Oiligodendrocyte differentiation promoter 1
CAS:Oiligodendrocyte differentiation promoter 1 is a promoter of oiligodendrocyte differentiation .Formula:C25H25Cl2NO5Purezza:98%Colore e forma:SolidPeso molecolare:490.38XY153
XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.Formula:C33H34FN3O4Colore e forma:SolidPeso molecolare:555.64CFT8634
CAS:CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.Formula:C37H45F3N6O5Colore e forma:SolidPeso molecolare:710.79WEHI-9625
CAS:WEHI-9625 is a tricyclic sulfone small molecule apoptosis inhibitor (EC50: 69 nM).Formula:C34H27NO5S2Purezza:98%Colore e forma:SolidPeso molecolare:593.71HP590
CAS:HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formula:C29H24F6N4O3Colore e forma:SolidPeso molecolare:590.52Glutaminyl Cyclase Inhibitor 3
CAS:Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formula:C24H32N6O2SPurezza:98%Colore e forma:SolidPeso molecolare:468.61Ici D1542
CAS:Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formula:C25H30N2O7Purezza:98%Colore e forma:SolidPeso molecolare:470.51Pyripyropene A
CAS:Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 μM).Formula:C31H37NO10Purezza:98%Colore e forma:SolidPeso molecolare:583.63SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Formula:C32H32N4O3Purezza:98%Colore e forma:SolidPeso molecolare:520.62SSR 146977
CAS:NK3 receptor antagonistFormula:C35H42Cl2N4O2Purezza:98%Colore e forma:SolidPeso molecolare:621.64Foroxymithine
CAS:Foroxymithine is an inhibitor of angiotensin-converting enzyme.Formula:C22H37N7O11Purezza:98%Colore e forma:SolidPeso molecolare:575.57Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Colore e forma:SolidPeso molecolare:157.21TAK-637
CAS:TAK-637 is a tachykinin 1 (NK1) receptor antagonist.Formula:C30H25F6N3O2Purezza:98%Colore e forma:SolidPeso molecolare:573.53RS 2135
CAS:RS 2135 is a novel class I antiarrhythmic agent to inhibit ischemia-induced ventricular arrhythmias.Formula:C18H21ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:332.83KRAS G12C inhibitor 44
KRAS G12C inhibitor 44: potent, oral, anti-cancer; halts cell growth in MIA PaCA-2, H358; effective in vivo. IC50: MIA-0.016μM, H358-0.028μM.Formula:C31H36ClFN6O2Colore e forma:SolidPeso molecolare:579.11KRAS inhibitor-8
CAS:KRAS inhibitor-8 is a potent KRAS G12C inhibitor.Formula:C26H24ClF4N5O3Purezza:98%Colore e forma:SolidPeso molecolare:565.95CS-003 HCl
CAS:CS-003 HCl is a TNRA - triple neurokinin receptor antagonist.Formula:C34H39Cl3N2O6SColore e forma:SolidPeso molecolare:710.1VEGFR-2/DHFR-IN-1
Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.Formula:C20H18ClNO4Colore e forma:SolidPeso molecolare:371.81RDN2150
CAS:RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69Formula:C28H29ClN8O4Colore e forma:SolidPeso molecolare:577.0320-HEDE
CAS:20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.Formula:C20H36O3Purezza:98%Colore e forma:SolidPeso molecolare:324.50KRAS G12C inhibitor 46
CAS:KRAS G12C inhibitor 46 is a potent inhibitor of KRAS G12C.Formula:C32H33F2N7O2Colore e forma:SolidPeso molecolare:585.65NVP-CGM097 sulfate
CAS:NVP-CGM097 sulfate is a potent and selective inhibitor of MDM2 (hMDM2, IC50 of 1.7±0.1 nM).Formula:C38H49ClN4O8SPurezza:98%Colore e forma:SolidPeso molecolare:757.34FCE-24379
CAS:FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.Formula:C20H22N4O2Colore e forma:SolidPeso molecolare:350.41(RS)-AMPA hydrobromide
CAS:AMPAR agonistFormula:C7H11BrN2O4Purezza:98%Colore e forma:SolidPeso molecolare:267.08IRAK4-IN-18
IRAK4-IN-18: Potent IRAK4 inhibitor (IC50: 15 nM), reduces IL23 in cells, prevents rat arthritis.Formula:C24H25FN6O3Colore e forma:SolidPeso molecolare:464.49(S)-Purvalanol B
CAS:(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is an inhibitor of cyclin-dependent kinase(CDK) .Formula:C20H25ClN6O3Purezza:98%Colore e forma:SolidPeso molecolare:432.9Heparastatin
CAS:Heparastatin is an inhibitor of heparanase.Formula:C8H11F3N2O5Purezza:98%Colore e forma:SolidPeso molecolare:272.18PPARα/γ agonist 1
PPARα/γ agonist 1 is a potent and dual PPARα/γ partial agonist which is a promising prototype for the research of dyslipidemia and diabetes.Formula:C18H19NO2Colore e forma:SolidPeso molecolare:281.35J-104871
CAS:J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.Formula:C38H32N2O12Purezza:98%Colore e forma:SolidPeso molecolare:708.67CB 30900
CAS:CB30900 is a novel and effective thymidylate synthase inhibitor.Formula:C31H32FN5O9Colore e forma:SolidPeso molecolare:637.61U 80215
CAS:U 80215 is an enzyme-competitive inhibitor.Formula:C42H60N8O6SColore e forma:SolidPeso molecolare:805.04CLK1/2-IN-1
CAS:CLK1/2-IN-1 is a CLK1 and CLK2 inhibitor and it also inhibits SRPK1 and SRPK2.Formula:C21H20F3N7OPurezza:98%Colore e forma:SolidPeso molecolare:443.42A1AR antagonist 1
Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).Formula:C18H14N4OColore e forma:SolidPeso molecolare:302.33Glyphosate-trimesium
CAS:Glyphosate-trimesium is a herbicide.Formula:C6H16NO5PSColore e forma:SolidPeso molecolare:245.23rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFormula:C24H30Cl3NOPurezza:98%Colore e forma:SolidPeso molecolare:454.86DS88790512
CAS:DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.Formula:C22H29N3O2Purezza:98%Colore e forma:SolidPeso molecolare:367.48AS2521780
CAS:AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).Formula:C30H41N7OSPurezza:98%Colore e forma:SolidPeso molecolare:547.76ZLWT-37
ZLWT-37: Oral CDK inhibitor, CDK9 IC50=0.002 µM, CDK2 IC50=0.054 µM; halts HCT116 cells at G2/M, induces apoptosis.Formula:C26H30ClN5OColore e forma:SolidPeso molecolare:464Iralukast (CGP 45715A)
CAS:Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.Formula:C38H37F3O8SColore e forma:SolidPeso molecolare:710.76UK-432097
CAS:UK 432097 is an adenosine A2A agonist.Formula:C40H47N11O6Colore e forma:SolidPeso molecolare:777.87LIT-001 free base
CAS:LIT-001, a nonpeptide OT-R agonist, enhances mouse autism-like behavior, with EC50=55 nM and Ki=226 nM.Formula:C28H33N7O2SPurezza:98%Colore e forma:SolidPeso molecolare:531.67FLT3/ITD-IN-1
FLT3/ITD-IN-1 inhibits FLT3-ITD with IC50s: 38.2 nM (FLT3) and 144.1 nM (ITD), and fights acute myeloid leukemia.Formula:C19H22N6O2Colore e forma:SolidPeso molecolare:366.42AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formula:C25H33NO3Colore e forma:SolidPeso molecolare:395.53RAD51-IN-6
CAS:RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)Formula:C27H40N3O5PSColore e forma:SolidPeso molecolare:549.66LXR antagonist 2
<p>LXR antagonist 2 inhibits adipogenesis, downregulates LXR genes, and reduces lipids in hyperlipidemic mice (LXRβ IC50: 0.36μM, LXRα IC50: 2.25μM).</p>Formula:C34H40N2O5SColore e forma:SolidPeso molecolare:588.76TRK-IN-12
CAS:TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.Formula:C18H19ClFN5O3SColore e forma:SolidPeso molecolare:439.89PF-5177624
CAS:PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.Formula:C25H25FN8O2Colore e forma:SolidPeso molecolare:488.52HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formula:C17H13ClF3N3O3Colore e forma:SolidPeso molecolare:399.75Ambuic acid
CAS:Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formula:C19H26O6Colore e forma:SolidPeso molecolare:350.41Metoquizine
CAS:Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48OUN58101
CAS:OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.Formula:C32H36N6O6Colore e forma:SolidPeso molecolare:600.66PSB 36
CAS:A1 adenosine receptor antagonistFormula:C21H30N4O3Purezza:98%Colore e forma:SolidPeso molecolare:386.49Homodestcardin
CAS:<p>Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.</p>Formula:C32H55N5O7Colore e forma:SolidPeso molecolare:621.81BILA 1906 BS
CAS:BILA 1906 BS is an inhibitor of substrate analog protease.Formula:C41H52N6O4SPurezza:98%Colore e forma:SolidPeso molecolare:724.95A2A receptor antagonist 2
A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).Formula:C25H28FN7O3Colore e forma:SolidPeso molecolare:493.53Belotecan
CAS:Belotecan (CKD-602) inhibits DNA topoisomerase I, blocks cell cycle, induces apoptosis, and is a camptothecin-derived anticancer agent.Formula:C25H27N3O4Colore e forma:SolidPeso molecolare:433.5(S)-MALT1-IN-5
CAS:(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.Formula:C17H17ClF2N6O3Colore e forma:SolidPeso molecolare:426.80A 70450
CAS:A 70450, an inhibitor of aspartyl proteinase, can be used as an antifungal agent and may have a role in HIV protease inhibition therapy.Formula:C42H71ClN6O5Purezza:98%Colore e forma:SolidPeso molecolare:775.50AKT-IN-11
AKT-IN-11 is one of the most potent antibacterial agents against human hepatocellular carcinoma Bel-7402 cell line (IC50: 1.15 μM).Formula:C27H27ClF3NO4Colore e forma:SolidPeso molecolare:521.96(S)-Seco-Duocarmycin SA
CAS:(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.Formula:C25H24ClN3O7Purezza:98%Colore e forma:SolidPeso molecolare:513.93L-Moses dihydrochloride
L-Moses (L-45) dihydrochloride is the first, potent, selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor (Kd: 126 nM).Formula:C21H26Cl2N6Colore e forma:SolidPeso molecolare:433.38KDOAM-25 trihydrochloride (2230731-99-2 free base)
KDOAM-25 trihydrochloride, a selective KDM5 inhibitor (IC50: 19-71 nM), boosts H3K4 methylation and hinders MM1S cell growth.Formula:C15H28Cl3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:416.77Teslexivir
CAS:Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.Formula:C35H36BrN3O4Purezza:98%Colore e forma:SolidPeso molecolare:642.58WF-47-JS03
<p>WF-47-JS03: RET kinase inhibitor, crosses blood-brain barrier, 500x more selective for KDR, IC50: 1.7 nM in Ba/F3 cells, 5.3 nM in LC-2/ad lung cancer cells.</p>Formula:C30H38N6O2Colore e forma:SolidPeso molecolare:514.66Gallinamide A
CAS:Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.Formula:C31H52N4O7Colore e forma:SolidPeso molecolare:592.77BRD50837
CAS:BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).Formula:C26H32ClN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:550.07Topoisomerase I/II inhibitor 2
Compound 1a inhibits Topoisomerase I/II, shrinks mouse liver tumors, IC50: 6.83/9.82 μM for LM9/Huh7 cells.Formula:C19H16N2O4Colore e forma:SolidPeso molecolare:336.34KRAS G12C inhibitor 33
CAS:KRAS G12C inhibitor 33 is a KRAS G12C inhibitor that can be used to study cancer.Formula:C30H33N7O3Colore e forma:SolidPeso molecolare:539.63CGS 22652
CAS:CGS 22652 has thromboxane receptor antagonism combined with thromboxane synthase inhibition.Formula:C22H29ClN2O4SColore e forma:SolidPeso molecolare:452.99Topoisomerase I/II inhibitor 3
Topoisomerase I/II inhibitor 3 suppresses cell growth and induces apoptosis in liver cancer by blocking PI3K/Akt/mTOR.Formula:C24H24N2O4Colore e forma:SolidPeso molecolare:404.46DS34942424
DS34942424 is an orally potent analgesic which did not exhibit mu opioid receptor agonist activity.Formula:C15H17FN2OColore e forma:SolidPeso molecolare:260.31Antidepressant agent 2
Antidepressant agent 2 showed significant antidepressant effects with a MED value of 0.1 mg/kg.Formula:C21H22ClFN2O3SColore e forma:SolidPeso molecolare:436.93AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formula:C26H22FN3O2SPurezza:98.04% - 98.92%Colore e forma:SolidPeso molecolare:459.54Thiolactomycin
CAS:Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).Formula:C11H14O2SPurezza:98%Colore e forma:SolidPeso molecolare:210.29Antitumor agent-42
Antitumor agent-42 inhibits microtubule multimerisation and NO release, exhibiting anti-angiogenic, colony-forming and apoptosis-inducing effects.Formula:C24H19BrN2O8SColore e forma:SolidPeso molecolare:575.39hCAII-IN-4
CAS:hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.Formula:C31H23NO9Colore e forma:SolidPeso molecolare:553.52Acetylpepstatin
CAS:Acetylpepstatin is an inhibitor of HIV-1 protease, HIV-2 protease, aspartyl protease.Formula:C33H61N5O11Purezza:98%Colore e forma:SolidPeso molecolare:703.875Lobaric acid
CAS:Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.Formula:C25H28O8Colore e forma:SolidPeso molecolare:456.48JH295 hydrate
JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.Formula:C18H18N4O3Colore e forma:SolidPeso molecolare:338.36U 75875
CAS:U 75875 is a protease inhibitor.Formula:C45H61N7O7Colore e forma:SolidPeso molecolare:812.01P2X receptor-1
P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.Formula:C14H14ClN3O3S2Colore e forma:SolidPeso molecolare:371.86Aristoforin
CAS:Aristoforin is a SIRT1 and SIRT2 inhibitor that induces cell cycle arrest, shows potent antitumor effects, and inhibits lymphangiogenesis in vivo.Formula:C37H54O6Colore e forma:SolidPeso molecolare:594.82Antiviral agent 15
Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).Formula:C27H24FN5OColore e forma:SolidPeso molecolare:453.51DENV-IN-6
CAS:DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.Formula:C23H26ClFN4OSColore e forma:SolidPeso molecolare:461Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Formula:C8H12N2S2Colore e forma:SolidPeso molecolare:200.32Gimatecan
CAS:Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.Formula:C25H25N3O5Purezza:98.47%Colore e forma:SolidPeso molecolare:447.48TLR7/8 antagonist 2
TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.Formula:C22H26FN5Colore e forma:SolidPeso molecolare:379.47CEP-14083
CAS:CEP-14083: potent ALK inhibitor, effective in NPM/ALK T-cell lymphoma, binds ATP site; IC50=11 nmol/L, also inhibits insulin receptor, preclinical efficacy.Formula:C31H30N6O2Colore e forma:SolidPeso molecolare:518.61GR 122222X
CAS:GR 122222X is an inhibitor of topoisomerase II.Formula:C26H35N5O11SPurezza:98%Colore e forma:SolidPeso molecolare:625.65Tofogliflozin
CAS:Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).Formula:C22H26O6Purezza:98%Colore e forma:SolidPeso molecolare:386.44(2S,4S)-Sacubitril
CAS:(2S,4S)-Sacubitril (Sacubitril Impurity C) is a stereoisomer derived from Sacubitril which is a potent NEP inhibitor.Formula:C24H29NO5Purezza:98%Colore e forma:SolidPeso molecolare:411.49MA242 free base
CAS:MA242 free base is a dual MDM2/NFAT1 inhibitor that triggers apoptosis in pancreatic cancer cells.Formula:C24H20ClN3O3SColore e forma:SolidPeso molecolare:465.95Sucistil
Sucistil is an active biochemical. hemoglobin sucistil (bovine) is an oxygen carrier [1].Formula:C9H15NO4SColore e forma:SolidPeso molecolare:233.28Oncopterin
CAS:Oncopterin is found in urine from patients with solid and blood cancers.Formula:C12H18N6O3Colore e forma:SolidPeso molecolare:294.31CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Colore e forma:SolidADP-2341
ADP-2341 is a soluble analog of FiVe1.Formula:C24H29Cl2N5O3Colore e forma:SolidPeso molecolare:506.43Microtubule inhibitor 2
Microtubule inhibitor 2: potent, selective, oral, induces ferroptosis, strong antitumor effect.Formula:C20H23NO7Colore e forma:SolidPeso molecolare:389.4Balanol
CAS:Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.Formula:C28H26N2O10Colore e forma:SolidPeso molecolare:550.51Cilobamine (free base)
CAS:Cilobamine: a stimulant antidepressant, inhibits norepinephrine-dopamine reuptake, based on dichloroisoprenaline structure.Formula:C17H23Cl2NOColore e forma:SolidPeso molecolare:328.28Pyridoxatin
CAS:Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.Formula:C15H21NO3Colore e forma:SolidPeso molecolare:263.33HG-12-6
CAS:HG-12-6 is a type II IRAK4 inhibitor, targeting its inactive form with an IC50 of 165 nM, and is used in autoimmunity and inflammation.Formula:C29H27F3N6O2SPurezza:98%Colore e forma:SolidPeso molecolare:580.62NU5455
CAS:NU5455 is a potent DNA-PKcs inhibitor, oral, boosts doxorubicin in liver tumors, amplifies topoisomerase inhibitors, no adverse effects.Formula:C34H33N3O5SColore e forma:SolidPeso molecolare:595.71XP-524
CAS:XP-524: BET & EP300 inhibitor, suppresses KRAS tumors in vivo, targets PDAC, boosts immune response.Formula:C30H28N6O3SColore e forma:SolidPeso molecolare:552.65BNTX maleate
CAS:δ1 opioid receptor antagonistFormula:C31H31NO8Purezza:98%Colore e forma:SolidPeso molecolare:545.58HDAC8-IN-2
HDAC8-IN-2 (5o) inhibits both smHDAC8 and hHDAC8 with IC50s of 0.27 μM, 0.32 μM, kills schistosome larvae, and lowers egg laying.Formula:C21H16N2O5Colore e forma:SolidPeso molecolare:376.36hCAII-IN-5
CAS:hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Formula:C29H18N2O7Colore e forma:SolidPeso molecolare:506.46AP5
CAS:AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Formula:C28H28FNO4Purezza:98%Colore e forma:SolidPeso molecolare:461.52A25822B
CAS:A25822B is an antifungal agent.Formula:C28H45NOPurezza:98%Colore e forma:SolidPeso molecolare:411.66Pralatrexate, (R)-
CAS:Pralatrexate is a high-affinity DHFR inhibitor targeting RFC-1, used in cancer treatment and immunosuppression.Formula:C23H23N7O5Purezza:98%Colore e forma:SolidPeso molecolare:477.47AChE-IN-24
AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.Formula:C22H30N2O4S2Colore e forma:SolidPeso molecolare:450.61Chitin synthase inhibitor 6
Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.Formula:C24H25N3O6Colore e forma:SolidPeso molecolare:451.47GSK1820795A
CAS:GSK1820795A: Telmisartan analog, selective hGPR132a antagonist, blocks yeast activation by N-acylamides, angiotensin II antagonist, partial PPARγ agonist.Formula:C35H34N8Colore e forma:SolidPeso molecolare:566.7K203
K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.Formula:C16H18Br2N4O2Colore e forma:SolidPeso molecolare:458.15LY3020371 hydrochloride
CAS:LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.Formula:C15H16ClF2NO5SColore e forma:SolidPeso molecolare:395.81DIDS
CAS:DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.Formula:C16H10N2O6S4Purezza:98%Colore e forma:SolidPeso molecolare:454.52Ribocil-C R enantiomer
Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.Formula:C21H21N7OSPurezza:98%Colore e forma:SolidPeso molecolare:419.5TMC353121
CAS:TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9).Formula:C32H42N6O3Purezza:≥98%Colore e forma:SolidPeso molecolare:558.71(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).Formula:C16H20N6OPurezza:98%Colore e forma:SolidPeso molecolare:312.37GP-1681
CAS:GP-1681, a G-protein coupled receptor (GPCR) agonist, is used potentially for the treatment of influenza infection.Formula:C24H30NaO5Purezza:98%Colore e forma:SolidPeso molecolare:421.48LY 235959
CAS:LY 235959 is a NMDA receptor antagonist.Formula:C11H20NO5PPurezza:98%Colore e forma:SolidPeso molecolare:277.25cis-RdRP-IN-5
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.Formula:C23H21N3O5Colore e forma:SolidPeso molecolare:419.43Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Formula:C26H26FN3O4Colore e forma:SolidPeso molecolare:463.5TAP311
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).Formula:C34H40F6N6O4Purezza:98%Colore e forma:SolidPeso molecolare:710.71SD-2590 HCl
CAS:SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.Formula:C22H26ClF3N2O7SPurezza:98%Colore e forma:SolidPeso molecolare:554.96Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Formula:C30H35NO11Colore e forma:SolidPeso molecolare:585.60PCSK9-IN-17
CAS:PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.Formula:C16H19N5OSColore e forma:SolidPeso molecolare:329.42KR-67607
CAS:KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Formula:C24H29Cl2F3N4O4SColore e forma:SolidPeso molecolare:597.48BMS-681
CAS:BMS-681 is a CCR2 antagonist blocking chemokine binding, aiding control of inflammatory and neurodegenerative diseases.Formula:C26H36F3N5OColore e forma:SolidPeso molecolare:491.59Luffolide
CAS:Luffolide, a Luffariella sponge metabolite, shares manoalide's anti-inflammatory traits and fully inhibits PLA2's cleavage of phosphatidylcholine.Formula:C27H40O6Colore e forma:SolidPeso molecolare:460.60B026
CAS:B026: Oral p300/CBP HAT inhibitor, IC50: p300 1.8 nM, CBP 9.5 nM; targets AR+ prostate cancer cells.Formula:C27H23F4N5O4Colore e forma:SolidPeso molecolare:557.5HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Colore e forma:Solid(+)-Sparteine sulfate pentahydrate
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.Formula:C15H38N2O9SColore e forma:SolidPeso molecolare:422.54GSK852
GSK852 is a potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor with pIC50 of 7.9.Formula:C24H26N2O4Colore e forma:SolidPeso molecolare:406.47DNA-PK-IN-8
CAS:DNA-PK-IN-8: Potent, selective oral DNA-PK inhibitor, IC50 = 0.8 nM, boosts anti-cancer effects with Doxorubicin.Formula:C19H22N8O2Colore e forma:SolidPeso molecolare:394.43Valopicitabine
CAS:<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formula:C15H24N4O6Purezza:98%Colore e forma:SolidPeso molecolare:356.37Lysyllysyllysine
CAS:Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.Formula:C18H38N6O4Purezza:98%Colore e forma:SolidPeso molecolare:402.53TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Formula:C24H34N4O2SColore e forma:SolidPeso molecolare:442.62Enpp-1-IN-12
ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.Formula:C17H19N5O3SColore e forma:SolidPeso molecolare:373.43Dopamine D3 receptor antagonist-1
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeuticFormula:C31H35Cl2N3O3Colore e forma:SolidPeso molecolare:568.53Deoxyfuconojirimycin hydrochloride
CAS:Deoxyfuconojirimycin hydrochloride acts as a specific competitive inhibitor targeting human liver α-L-fucosidase.Formula:C6H14ClNO3Colore e forma:SolidPeso molecolare:183.63HDAC6-IN-13
HDAC6-IN-13: potent, selective HDAC6 inhibitor; oral; IC50=0.019μM; targets HDAC1/2/3; crosses blood-brain barrier; anti-inflammatory.Formula:C23H22N4OColore e forma:SolidPeso molecolare:370.45MsbA-IN-3
MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).Formula:C24H22Cl2N2O4SColore e forma:SolidPeso molecolare:505.41A1/A3 AR antagonist 1
<p>Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.</p>Formula:C24H18N2O3SColore e forma:SolidPeso molecolare:414.48OMDM169
CAS:OMDM169: potent/selective MAGL inhibitor, raises 2-AG, analgesic via cannabinoid receptors, IC50: 0.13-0.41μM in rat/COS-7, inactive at CB1/CB2.Formula:C25H45NO5Purezza:98%Colore e forma:SolidPeso molecolare:439.63D1R antagonist 1
CAS:Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formula:C22H26BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:448.35PDE4-IN-5
PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.Formula:C21H28N2O3Colore e forma:SolidPeso molecolare:356.46Anticancer agent 36
Compound 11: Sulfonylurea derivative, antimicrobial, anticancer; MIC 0.039-0.156 mg/mL; A549 IC50: 19.7 μg/mL, PC3 IC50: 11.9 μg/mL.Formula:C21H17N3O3S2Colore e forma:SolidPeso molecolare:423.51L 365209
CAS:L 365209 is an oxytocin antagonist.Formula:C40H50N8O6Purezza:98%Colore e forma:SolidPeso molecolare:738.88DC4SMe
CAS:DC4SMe, a prodrug for targeted tumor therapy and ADC synthesis, has IC50s: 1.9 nM (Ramos), 2.9 nM (Namalwa), 1.8 nM (HL60/s).Formula:C35H31ClN5O7PS2Purezza:98%Colore e forma:SolidPeso molecolare:764.21Hydrolyzed Fumonisin B2
CAS:Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. It exhibits phytotoxicity.Formula:C22H47NO4Purezza:98%Colore e forma:SolidPeso molecolare:389.61VEGFR-2-IN-5 hydrochloride
VEGFR-2-IN-5 hydrochloride is an effective VEGFR2 inhibitor.Formula:C19H25ClN8Colore e forma:SolidPeso molecolare:400.91TAS-117 hydrochloride
TAS-117 HCl: potent oral Akt inhibitor (Akt1 IC50: 4.8nM, Akt2: 1.6nM, Akt3: 44nM), boosts anti-myeloma effects, induces cell death.Formula:C26H25ClN4O2Colore e forma:SolidPeso molecolare:460.96Tubulin inhibitor 15
Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].Formula:C16H12FNO2Colore e forma:SolidPeso molecolare:269.27Stauprimide
CAS:Stauprimide inhibits MYC by blocking NME2, reducing MYC transcription in ESCs.Formula:C35H28N4O5Purezza:98%Colore e forma:SolidPeso molecolare:584.62SARS-CoV-2 nsp14-IN-2
SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.Formula:C21H21N5O5SColore e forma:SolidPeso molecolare:455.49T-3861174
CAS:T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.Formula:C26H25FN6O2Colore e forma:SolidPeso molecolare:472.51AS-1940477 hydrobromide
CAS:AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.Formula:C24H23BrFN5O2Colore e forma:SolidPeso molecolare:512.38α-Glucosidase-IN-12
α-Glucosidase-IN-12 is a potent inhibitor of α-glucosidase (IC50: 10.20 μM).Formula:C25H30N4O4S2Colore e forma:SolidPeso molecolare:514.66SARS-CoV-2-IN-8
SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).Formula:C35H38N6O3Colore e forma:SolidPeso molecolare:590.71OP-2507
CAS:OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.Formula:C25H41NO4Purezza:98%Colore e forma:SolidPeso molecolare:419.6TBK1/IKKε-IN-1
CAS:TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).Formula:C28H26N4O5Purezza:98%Colore e forma:SolidPeso molecolare:498.53BRD7539
CAS:BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.Formula:C23H22FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:391.44CXCR7 modulator 2
CAS:CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.Formula:C29H42N6O3Colore e forma:SolidPeso molecolare:522.68EGFR-IN-38
CAS:EGFR-IN-38: low-toxic acrylamide-derived EGFR inhibitor, targets NSCLC, patented for research on EGFR mutation-related diseases.Formula:C25H24ClN7O2Colore e forma:SolidPeso molecolare:489.96Kendomycin
CAS:Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Formula:C29H42O6Colore e forma:SolidPeso molecolare:486.64BRD4 Inhibitor-17
BRD4 Inhibitor-17: Potent with 0.33 μM IC50; modulates gene expression, may counter arsenic toxicity.Formula:C16H16FN3O3SColore e forma:SolidPeso molecolare:349.38Ophiobolin C
CAS:inhibitor of human CCR5 binding to HIV-1 gp120Formula:C25H38O3Purezza:98%Colore e forma:SolidPeso molecolare:386.57ACT 178882
CAS:ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Formula:C33H38Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:647.03AKN-028 acetate
AKN-028 acetate: an oral TK inhibitor for AML research, targets FLT3 with IC50 of 6 nM, inhibits autophosphorylation, and induces apoptosis.Formula:C19H18N6O2Colore e forma:SolidPeso molecolare:362.39Vimirogant hydrochloride
Vimirogant (VTP-43742) HCl: Oral, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM), >1000x selectivity over RORα/β, targets Th17, not Th1/2/Treg.Formula:C27H36ClF3N4O3SColore e forma:SolidPeso molecolare:588.21487OXS007417
OXS007417 induces AML cell differentiation at 48 nM EC50 and shows potent in vivo antitumor effects.Formula:C20H14F3N3OColore e forma:SolidPeso molecolare:369.34CCW 28-3
CAS:CCW 28-3 is a novel potent covalent BRD4 degrader, degrading BRD4 in a proteasome- and RNF4-dependent manner without inhibiting RNF4 autoubiquitination activityFormula:C44H42Cl2N6O4SColore e forma:SolidPeso molecolare:821.81CYP1B1-IN-2
CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].Formula:C20H11F3O2Colore e forma:SolidPeso molecolare:340.3Motuporin
CAS:Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).Formula:C40H57N5O10Colore e forma:SolidPeso molecolare:767.91
