Inibitori
Gli inibitori sono molecole che si legano a enzimi, recettori o altre proteine per ridurre o bloccare la loro attività biologica. Questi composti sono ampiamente utilizzati nella ricerca per studiare le vie biologiche, comprendere i meccanismi delle malattie e sviluppare farmaci terapeutici. Gli inibitori svolgono un ruolo cruciale nel trattamento di varie malattie, tra cui il cancro, le malattie cardiovascolari e le infezioni. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità per supportare le tue ricerche in biochimica, biologia cellulare e sviluppo farmaceutico.
Sottocategorie di "Inibitori"
- Angiogenesi(2.523 prodotti)
- Apoptosi(5.792 prodotti)
- Ciclo cellulare/Checkpoint(4.449 prodotti)
- Cromatina/Epigenetica(2.238 prodotti)
- Segnalazione citoscheletrica(1.383 prodotti)
- Danno al DNA/Riparazione del DNA(2.825 prodotti)
- Endocrinologia/Ormoni(3.507 prodotti)
- Enzima(3.640 prodotti)
- Proteina G/GPCR(8.333 prodotti)
- Immunologia e infiammazione(3.526 prodotti)
- Virus dell'influenza(296 prodotti)
- Segnalazione JAK/STAT(404 prodotti)
- Segnalazione MAPK(1.202 prodotti)
- Trasportatore di membrana/canale ionico(2.790 prodotti)
- Metabolismo(9.448 prodotti)
- Microbiologia/Virologia(6.981 prodotti)
- Neuroscienza(9.926 prodotti)
- Altri inibitori(37.926 prodotti)
- Ossidazione-riduzione(41 prodotti)
- Segnalazione PI3K/Akt/mTOR(1.400 prodotti)
- Proteasi/Proteasoma(1.597 prodotti)
- Cellule staminali e Derivati(831 prodotti)
- Adattatori Tirosin-chinasi(2.016 prodotti)
- Ubiquitinazione(1.650 prodotti)
Mostrare 16 più sottocategorie
Trovati 66641 prodotti di "Inibitori"
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RMS5
CAS:<p>RMS5: hambanine analogue, inhibits P-gp, anti-cancer with cytotoxic, anti-proliferative effects, reduces Bcl-2 proteins, cleaves PARP.</p>Formula:C35H38N2O5SColore e forma:SolidPeso molecolare:598.75BTK inhibitor 18
<p>BTK inhibitor 18 is a selective, potent, covalent, orally active Btk inhibitor (IC50: 142 nM) that exhibits anti-inflammatory effects.</p>Formula:C29H25N5O4S2Colore e forma:SolidPeso molecolare:571.67Butaprost
CAS:<p>Butaprost: EP2 receptor agonist, EC50=33 nM, Ki=2.4 μM (murine), reduces fibrosis via TGF-β/Smad2.</p>Formula:C24H40O5Purezza:98%Colore e forma:SolidPeso molecolare:408.57Glutamate-5-kinase-IN-1
<p>Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.</p>Formula:C20H18N2OColore e forma:SolidPeso molecolare:302.37Anticancer agent 17
<p>Anticancer agent 17 was effective against HeLa cells (IC50: 0.19 μM) and A2780 cells (IC50: 0.09 μM).</p>Formula:C27H34BrN3OColore e forma:SolidPeso molecolare:496.48EBI-907
CAS:<p>EBI-907 is a potent, oral B-RafV600E inhibitor with an IC50 of 4.9 nM, over 10x stronger than Vemurafenib, and effective against key cancer kinases.</p>Formula:C23H21ClF2N4O3SColore e forma:SolidPeso molecolare:506.95E 5090
CAS:<p>E5090 is a novel orally active inhibitor of IL-1 generation. It also has anti-inflammatory properties.</p>Formula:C19H20O5Purezza:98%Colore e forma:SolidPeso molecolare:328.36rel-SB-612111 hydrochloride
CAS:<p>NOP receptor antagonist</p>Formula:C24H30Cl3NOPurezza:98%Colore e forma:SolidPeso molecolare:454.86BMS-681
CAS:<p>BMS-681 is a CCR2 antagonist blocking chemokine binding, aiding control of inflammatory and neurodegenerative diseases.</p>Formula:C26H36F3N5OColore e forma:SolidPeso molecolare:491.59Tubulin polymerization-IN-34
<p>"Tubulin-IN-34 inhibits oxazolylisoindole microtubule assembly, selective for VL51 lymphoma."</p>Formula:C31H35N3O6Colore e forma:SolidPeso molecolare:545.63β-N-Acetyl-D-hexosaminidase-IN-1
<p>β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase.</p>Formula:C18H13F2NO2SColore e forma:SolidPeso molecolare:345.36FLT3/ITD-IN-1
<p>FLT3/ITD-IN-1 inhibits FLT3-ITD with IC50s: 38.2 nM (FLT3) and 144.1 nM (ITD), and fights acute myeloid leukemia.</p>Formula:C19H22N6O2Colore e forma:SolidPeso molecolare:366.42NYX-2925
CAS:<p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>Formula:C14H23N3O4Colore e forma:SolidPeso molecolare:297.35Enpp-1-IN-7
<p>Enpp-1-IN-7: potent enpp-1 inhibitor, broad specificity, potential in cancer/infectious disease research. (WO2021203772A1)</p>Formula:C18H19N7O4SColore e forma:SolidPeso molecolare:429.45GLP-1R agonist 8
CAS:<p>GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).</p>Formula:C33H32N4O5Colore e forma:SolidPeso molecolare:564.63ErSO-DFP
<p>ErSO-DFP activates a-UPR, targets ERα+ cancer cells with high selectivity, and effectively reduces MCF-7 tumours.</p>Formula:C20H17F5N2O2Colore e forma:SolidPeso molecolare:412.35CH-38083
CAS:<p>CH-38083 is a selective and effective alpha-2 adrenoceptors antagonist.</p>Formula:C18H24ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:337.84A 70450
CAS:<p>A 70450, an inhibitor of aspartyl proteinase, can be used as an antifungal agent and may have a role in HIV protease inhibition therapy.</p>Formula:C42H71ClN6O5Purezza:98%Colore e forma:SolidPeso molecolare:775.50CK2-IN-3
<p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>Formula:C22H26N4O7Colore e forma:SolidPeso molecolare:458.46A-9758
CAS:<p>A-9758: RORγt selective inverse agonist, IC50 5nM, inhibits IL-17A, Th17, and treats psoriasis.</p>Formula:C25H23Cl2F3N2O3Purezza:98%Colore e forma:SolidPeso molecolare:527.36Dazucorilant
CAS:<p>Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.</p>Formula:C29H22F4N4O3SColore e forma:SolidPeso molecolare:582.57SHP2-IN-9
<p>SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.</p>Formula:C20H20FN3O2SColore e forma:SolidPeso molecolare:385.46Cilobamine (free base)
CAS:<p>Cilobamine: a stimulant antidepressant, inhibits norepinephrine-dopamine reuptake, based on dichloroisoprenaline structure.</p>Formula:C17H23Cl2NOColore e forma:SolidPeso molecolare:328.28GLS1 Inhibitor-6
<p>GLS1 Inhibitor-6: IC50=68nM, 220x more selective for GLS2, has anti-tumor and pro-apoptosis effects.</p>Formula:C37H52N6O3SColore e forma:SolidPeso molecolare:660.91Carnostatine
<p>Carnostatine (SAN9812), a potent CN1 inhibitor with 11 nM K i, may boost renal carnosine to treat DN.</p>Formula:C10H16N4O4Purezza:98%Colore e forma:SolidPeso molecolare:256.26Cilengitide hydrochloride
CAS:<p>Cilengitide hydrochloride is a salt that may combat cancer by blocking specific integrins, disrupting cell interactions and angiogenesis.</p>Formula:C27H41ClN8O7Colore e forma:SolidPeso molecolare:625.12Anticancer agent 14
<p>Anticancer agent 14: a potent breast cancer inhibitor; induces cell death, disrupts mito. membrane potential (IC50: 0.20-0.65 μM).</p>Formula:C29H34N2O3Colore e forma:SolidPeso molecolare:458.59Asimicin
CAS:<p>Asimicin is a effective complex I inhibitor.</p>Formula:C37H66O7Purezza:98%Colore e forma:SolidPeso molecolare:622.92FGFR4-IN-9
<p>FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.</p>Formula:C24H22ClF3N4O4Colore e forma:SolidPeso molecolare:522.9Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formula:C27H24FN5OColore e forma:SolidPeso molecolare:453.51EGFR-IN-3
<p>EGFR-IN-3 is an EGFR inhibitor with antitumor activity.EGFR-IN-3 inhibits EGFRwt-TK, induces apoptosis (cell death), and can block cells in the G2/M phase.</p>Formula:C24H18F4N6O2SPurezza:98.1%Colore e forma:SolidPeso molecolare:530.5Hydrolyzed Fumonisin B2
CAS:<p>Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. It exhibits phytotoxicity.</p>Formula:C22H47NO4Purezza:98%Colore e forma:SolidPeso molecolare:389.61PSMA-1007
CAS:<p>PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.</p>Formula:C49H55FN8O16Colore e forma:SolidPeso molecolare:1030.01HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Formula:C23H26N2O4SColore e forma:SolidPeso molecolare:426.53Calcipotriol Impurity C
CAS:<p>Calcipotriol Impurity C is the impurity of Calcipotriol. Calcipotriol is a VDR-like receptors ligand.</p>Formula:C27H40O3Purezza:98%Colore e forma:SolidPeso molecolare:412.614α-Glucosidase-IN-19
<p>Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 μM) with antidiabetic effects.</p>Formula:C31H25NOSColore e forma:SolidPeso molecolare:459.6ODN 2088
CAS:<p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>Colore e forma:SolidCA IX-IN-1
<p>CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.</p>Formula:C16H22N4O8SColore e forma:SolidPeso molecolare:430.43IRL 2500
CAS:<p>IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.</p>Formula:C36H35N3O4Purezza:99.36%Colore e forma:White Crystalline SolidPeso molecolare:573.68L-739750
CAS:<p>L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.</p>Formula:C23H39N3O6S2Purezza:98%Colore e forma:SolidPeso molecolare:517.7PF 03709270
CAS:<p>PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.</p>Formula:C19H27NO7S3Purezza:98%Colore e forma:SolidPeso molecolare:477.61SI-109
CAS:<p>SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.</p>Formula:C40H44F2N7O9PPurezza:98%Colore e forma:SolidPeso molecolare:835.79PD 140376
CAS:<p>PD 140376: Selective CCK-B/gastrin receptor antagonist radioligand for guinea pig stomach & brain.</p>Formula:C33H40N4O5Purezza:98%Colore e forma:SolidPeso molecolare:572.69RET-IN-7
CAS:<p>RET-IN-7 exhibits strong inhibitory effects against RET kinase in vitro and shows significant efficacy in treating RET-driven tumor xenografts in mice through</p>Formula:C22H24ClFN6O2Colore e forma:SolidPeso molecolare:458.92MK-7445
CAS:<p>MK-7445 is a conformationally constrained inhibitor of non-nucleoside reverse transcriptase.</p>Formula:C21H13Cl2N7OColore e forma:SolidPeso molecolare:450.28Glyphosate-trimesium
CAS:<p>Glyphosate-trimesium is a herbicide.</p>Formula:C6H16NO5PSColore e forma:SolidPeso molecolare:245.23Tylophorinidine
CAS:<p>Tylophorinidine is an antifungal agent that has shown to inhibit cell growth.</p>Formula:C22H23NO4Colore e forma:SolidPeso molecolare:365.42LSD1/2-IN-4
<p>LSD1/2-IN-4, a PCPA derivative, inhibits LSD1 (Ki 0.11 μM) & LSD2 (Ki 130 μM), potentially useful in T-cell leukemia research.</p>Formula:C9H8BrF2NColore e forma:SolidPeso molecolare:248.072,3-dinor-11β-Prostaglandin F2α
CAS:<p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>Formula:C18H30O5Colore e forma:SolidPeso molecolare:326.43CFT8634
CAS:<p>CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.</p>Formula:C37H45F3N6O5Colore e forma:SolidPeso molecolare:710.79CCG258747
CAS:<p>CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.</p>Formula:C28H27FN4O4Colore e forma:SolidPeso molecolare:502.54Beloxepin
CAS:<p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>Formula:C19H21NO2Purezza:98%Colore e forma:SolidPeso molecolare:295.38BTK-IN-7
<p>BTK-IN-7 is a potent inhibitor for BTK with 4.0 nM IC50, highly selective over ITK and EGFR, showing strong antitumor activity.</p>Formula:C30H32N6O4Colore e forma:SolidPeso molecolare:540.61Hymenidin
CAS:<p>Hymenidin, isolated from the Okinawan sponge Hymeniacidon sp., is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor.</p>Formula:C11H12BrN5OPurezza:96.85% - 99.52%Colore e forma:SolidPeso molecolare:310.15FTI-2148
CAS:<p>FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.</p>Formula:C24H28N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:452.57IACS-8779
CAS:<p>IACS-8779 is a potent STING agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.</p>Formula:C21H25N9O10P2S2Purezza:98%Colore e forma:SolidPeso molecolare:689.55DC41SMe
CAS:<p>DC41SMe, a DC1 derivative and CC-1065 analogue, targets cancer with 18-25 pM IC50 against Ramos, Namalwa, HL60/s cells.</p>Formula:C38H36ClN5O4S2Purezza:98%Colore e forma:SolidPeso molecolare:726.31A1/A3 AR antagonist 1
<p>Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.</p>Formula:C24H18N2O3SColore e forma:SolidPeso molecolare:414.48Dehydelone
CAS:<p>Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.</p>Formula:C27H39NO5SColore e forma:SolidPeso molecolare:489.67MtTMPK-IN-3
CAS:<p>MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.</p>Formula:C23H23Cl2N3O3Colore e forma:SolidPeso molecolare:460.35MS8815
CAS:<p>MS8815 is a selective EZH2 PROTAC degrader with IC50 of 8.6 nM, used in triple-negative breast cancer research.</p>Formula:C65H87N9O8SColore e forma:SolidPeso molecolare:1154.51MS117
<p>MS117 is a first-in-class and cell-active irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6) (IC50 = 18 nM) [1].</p>Formula:C17H22N4OColore e forma:SolidPeso molecolare:298.38YW3-56
CAS:<p>YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.</p>Formula:C27H32ClN5O2Colore e forma:SolidPeso molecolare:494.03R-96544 hydrochloride
CAS:<p>5-HT2 receptor antagonist</p>Formula:C22H29NO3Purezza:98%Colore e forma:SolidPeso molecolare:355.47L 671776
CAS:<p>L 671776 is an inositol monophosphatase inhibitor.</p>Formula:C23H32O5Purezza:98%Colore e forma:SolidPeso molecolare:388.5BRD4 D1-IN-1
<p>BRD4 D1-IN-1 selectively inhibits BRD4 D1 (IC50 <0.092 μM, Kd 18 nM) with >500-fold specificity versus D2.</p>Formula:C32H37F3N6OColore e forma:SolidPeso molecolare:578.67LX2761
CAS:<p>LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.</p>Formula:C32H47N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:601.80Plumbemycin B
CAS:<p>Plumbemycin B is isolated from Streptomyces plumbeus; an L-threonine antagonist.</p>Formula:C12H21N4O8PColore e forma:SolidPeso molecolare:380.29PLAP-IN-1
CAS:<p>PLAP-IN-1: Potent, selective inhibitor of PLAP, IC50 of 32 nM; doesn't notably inhibit TNAP.</p>Formula:C25H21Cl2N3O5Colore e forma:SoildPeso molecolare:514.36(S)-Seco-Duocarmycin SA
CAS:<p>(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.</p>Formula:C25H24ClN3O7Purezza:98%Colore e forma:SolidPeso molecolare:513.93Arverapamil
CAS:<p>Arverapamil is a chiral metabolite of Verapamil.</p>Formula:C26H36N2O4Colore e forma:SolidPeso molecolare:440.58ZLWT-37
<p>ZLWT-37: Oral CDK inhibitor, CDK9 IC50=0.002 µM, CDK2 IC50=0.054 µM; halts HCT116 cells at G2/M, induces apoptosis.</p>Formula:C26H30ClN5OColore e forma:SolidPeso molecolare:464RET-IN-11
<p>RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.</p>Formula:C27H30FN9OColore e forma:SolidPeso molecolare:515.59Cap-dependent endonuclease-IN-6
CAS:<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Formula:C23H21N3O3SColore e forma:SolidPeso molecolare:419.5TrxR-IN-2
<p>TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.</p>Formula:C22H22N4O4Colore e forma:SolidPeso molecolare:406.43Anticancer agent 44
<p>Anticancer agent 44 induces apoptosis, is selective, cytotoxic to cancer cells, and minimally toxic to human lymphocytes.</p>Formula:C22H13Cl2N3O5S2Colore e forma:SolidPeso molecolare:534.39DMP-728 free base
CAS:<p>DMP-728 free base is a highly potent and selective GPIIbDIIa antagonist</p>Formula:C25H36N8O7Colore e forma:SolidPeso molecolare:560.60GS-9822
CAS:<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formula:C36H39ClN4O4SColore e forma:SolidPeso molecolare:659.24HDAC-IN-33
<p>HDAC-IN-33 inhibits HDAC1/2/6 (IC50: 24/46/47 nM), exhibits potent antitumor activity in vitro and in vivo, and activates antitumor immunity.</p>Formula:C21H25N3O3Colore e forma:SolidPeso molecolare:367.44Bim-IN-1
<p>Bim-IN-1 is a potent inhibitor of Bim expression with low toxicity, Bim-IN-1 reduces Bim expression levels with little inhibition of protein kinase A.</p>Formula:C19H20Cl2FNO2SColore e forma:SolidPeso molecolare:416.34MRTX849 ethoxypropanoic acid
CAS:<p>MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.</p>Formula:C37H43ClFN7O5Colore e forma:SolidPeso molecolare:720.24PAD2-IN-1 hydrochloride
<p>PAD2-IN-1 hydrochloride: potent, selective PAD2 inhibitor; 95x less on PAD4, 79x less on PAD3; benzimidazole derivative.</p>Formula:C25H30ClFN6O3Colore e forma:SolidPeso molecolare:517Tauro-ω-muricholic acid sodium
<p>Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin.</p>Formula:C26H44NNaO7SColore e forma:SolidPeso molecolare:537.68TA-316
CAS:<p>Agent induces megakaryocytes/platelets from stem cells to treat thrombopenia.</p>Formula:C28H25BrN4O5S2Purezza:98%Colore e forma:SolidPeso molecolare:641.56HOE-288
CAS:<p>HOE-288 is a converting enzyme (CE) inhibitor.</p>Formula:C27H38N2O5Colore e forma:SolidPeso molecolare:470.60Org-31710
CAS:<p>Org-31710 is a progesterone receptor antagonist potentially for contraception.</p>Formula:C30H39NO2Purezza:98%Colore e forma:SolidPeso molecolare:445.64RMG8-8
<p>RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).</p>Formula:C41H78N8O5Colore e forma:SolidPeso molecolare:763.11KT5926
CAS:<p>KT5926 selectively inhibits myosin light chain kinase and NGF-dependent neurite growth; it's a K-252a analogue.</p>Formula:C30H27N3O6Purezza:98%Colore e forma:SolidPeso molecolare:525.55Tamitinol
CAS:<p>Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.</p>Formula:C12H20N2OSPurezza:98%Colore e forma:SolidPeso molecolare:240.37SB-612111
CAS:<p>SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.</p>Formula:C24H29Cl2NOColore e forma:SolidPeso molecolare:418.40Antioxidant agent-8
<p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.</p>Formula:C13H12O5Colore e forma:SolidPeso molecolare:248.23Holothurinogenin
CAS:<p>Holothurinogenin, as a lanosterol derivative, has toxic to nerve tissue.</p>Formula:C30H46O4Colore e forma:SolidPeso molecolare:470.68GSK2578999A
CAS:<p>GSK2578999A is a betulin derivative with antitumor activity.</p>Formula:C46H62ClNO7Purezza:98%Colore e forma:SolidPeso molecolare:776.44JAK3-IN-11
CAS:<p>JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.</p>Formula:C23H23N5O2Colore e forma:SolidPeso molecolare:401.46DFBTA
<p>DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.</p>Formula:C18H10ClF2NO3SColore e forma:SolidPeso molecolare:393.79BACE1-IN-4
CAS:<p>BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.</p>Formula:C21H23F2N5O4S2Purezza:98%Colore e forma:SolidPeso molecolare:511.57LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Formula:C20H19FN6O3Colore e forma:SolidPeso molecolare:410.4AZ14145845
<p>AZ14145845 is an in vivo potent and highly selective type I1/2 Mer/Axl bispecific kinase inhibitor.</p>Formula:C32H35N9OColore e forma:SolidPeso molecolare:561.68CDK/HDAC-IN-1
<p>CDK/HDAC-IN-1 inhibits CDK2/4/6 & HDAC6 with IC50s: 60.9, 276, 27.2, and 128.6 nM respectively.</p>Formula:C20H18N4O4Colore e forma:SolidPeso molecolare:378.38DS01080522
<p>DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.</p>Formula:C23H20Cl2N4O3Colore e forma:SolidPeso molecolare:471.34CXCR7 antagonist-1 hydrochloride
CAS:<p>CXCR7 antagonist-1 hydrochloride blocks SDF-1 and I-TAC from CXCR7; may prevent cancer and inflammation.</p>Formula:C21H20ClFN6OColore e forma:SolidPeso molecolare:426.87Diguanosine 5′-triphosphate lithium
<p>Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphate and a virus-specific oligonucleotide.Diguanosine 5′-triphosphate lithium is required</p>Formula:C20H27N10O18P3·xLiColore e forma:SolidNMDAR/HDAC-IN-1
<p>Compound 9d is a dual NMDAR and HDAC inhibitor with high NMDAR affinity (Ki=0.59 μM) and inhibits HDAC1-3,6,8; crosses the blood-brain barrier.</p>Formula:C22H28N2O3Colore e forma:SolidPeso molecolare:368.47PF-4693627
CAS:<p>PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).</p>Formula:C26H29Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:502.43CDK-IN-9
<p>CDK-IN-9: A potent CDK inhibitor, gels to enhance CDK12/DDB1 binding, targets CDK2/E (IC50: 4 nM), induces apoptosis via dephosphorylation.</p>Formula:C21H24N8SColore e forma:SolidPeso molecolare:420.5316(S)-Iloprost
CAS:<p>Iloprost, a potent prostacyclin analog, binds to human IP & EP1 receptors with high affinity; inhibits platelet aggregation effectively.</p>Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.49BAY-364
CAS:<p>BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+</p>Formula:C23H19N3O4Colore e forma:SolidPeso molecolare:401.41MCTR1
CAS:<p>MCTR1, a pro-resolving mediator derived from DHA, promotes tissue repair and reduces inflammation by enhancing phagocytosis and decreasing eicosanoids.</p>Formula:C32H47N3O9SColore e forma:SolidPeso molecolare:649.8NNC 55-0396
CAS:<p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>Formula:C30H40Cl2FN3O2Purezza:99.00%Colore e forma:SolidPeso molecolare:564.56ATM Inhibitor-3
<p>ATM Inhibitor-3 selectively inhibits ATM (IC50: 0.71 nM), targets PI3K kinase family, and is metabolically stable.</p>Formula:C25H29FN6O3Colore e forma:SolidPeso molecolare:480.53BMS-554417
CAS:<p>BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.</p>Formula:C28H30ClN7O2Colore e forma:SolidPeso molecolare:532.049(R)-HETE
CAS:<p>9(R)-HETE, 50% of racemic mix, activates RXRγ 1.5x at 300 nM; identified by HPLC comparison.</p>Formula:C20H32O3Colore e forma:SolidPeso molecolare:320.47Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Formula:C26H40N2O8Purezza:98%Colore e forma:SolidPeso molecolare:508.612PI3K-IN-27
CAS:<p>PI3K-IN-27 is a potent PI3K inhibitor, relevant for cancer and immune disease research. See patent WO2021233227A1.</p>Formula:C30H26F2N6O2SColore e forma:SolidPeso molecolare:572.63Estrogen receptor antagonist 7
CAS:<p>ER antagonist 7, compound 13, inhibits ERs, halts breast/ovarian cancer cell growth, has anticancer properties.</p>Formula:C23H17N3O4Colore e forma:SolidPeso molecolare:399.4FGI-106
CAS:<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Formula:C28H38N6Purezza:98%Colore e forma:SolidPeso molecolare:458.64JAK2 JH2 binder-1
CAS:<p>JAK2 JH2 binder-1: potent, selective, Ki=37.1 nM, potential for studying myeloproliferative neoplasms.</p>Formula:C29H25N7O6SColore e forma:SolidPeso molecolare:599.62Revamilast sodium
CAS:<p>Revamilast sodium, also known as GRC4039 sodium, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis</p>Formula:C18H8Cl2F2N3NaO4Colore e forma:SolidPeso molecolare:462.17DG013A
CAS:<p>DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.</p>Formula:C27H37N4O4PColore e forma:SolidPeso molecolare:512.58LSD1-IN-16
<p>LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.</p>Formula:C20H18N2OSColore e forma:SolidPeso molecolare:334.43Tubulin inhibitor 13
CAS:<p>Tubulin inhibitor 13 (E27), IC50 16.1 μM, blocks tubulin polymerization, cancer cell migration, and invasion, induces apoptosis.</p>Formula:C25H21N3O4Colore e forma:SolidPeso molecolare:427.45MRGPRX1 agonist 4
<p>Potent, oral MRGPRX1 agonist 4 modulates receptor positively (EC50: 0.1 μM) and reduces mice's thermal allergy response.</p>Formula:C23H17Cl2F3N2O2SColore e forma:SolidPeso molecolare:513.36Antitumor agent-42
<p>Antitumor agent-42 inhibits microtubule multimerisation and NO release, exhibiting anti-angiogenic, colony-forming and apoptosis-inducing effects.</p>Formula:C24H19BrN2O8SColore e forma:SolidPeso molecolare:575.39Aplaviroc hydrochloride
CAS:<p>Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.</p>Formula:C33H44ClN3O6Colore e forma:SolidPeso molecolare:614.17PF-06462894
CAS:<p>PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.</p>Formula:C18H23N3O3Purezza:98%Colore e forma:SolidPeso molecolare:329.39ACSS2-IN-1
CAS:<p>ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.</p>Formula:C27H25ClN6O2Colore e forma:SolidPeso molecolare:500.98Antibacterial agent 69
<p>Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).</p>Formula:C24H19N3O4SColore e forma:SolidPeso molecolare:445.49S1P1 agonist 5
<p>Selective oral S1P1 agonist 5 inhibits lymphocyte drainage, potential for MS research.</p>Formula:C23H24ClN2NaO4Colore e forma:SolidPeso molecolare:450.89Fostriecin (free base)
CAS:<p>Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.</p>Formula:C19H27O9PColore e forma:SolidPeso molecolare:430.39MAO A/HDAC-IN-1
<p>MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.</p>Formula:C21H24ClN3O3Colore e forma:SolidPeso molecolare:401.89Ambrosin
CAS:<p>Ambrosin is a sesquiterpene lactone and a potent NF-κβ inhibitor. It is currently being studied as a potential lead drug for Alzheimer disease therapeutics.</p>Formula:C15H18O3Colore e forma:SolidPeso molecolare:246.3(R)-CSN5i-3
CAS:<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Formula:C28H29F2N5O2Purezza:99.76% - 99.97%Colore e forma:SolidPeso molecolare:505.56ND-654
CAS:<p>ND-654 is an acetyl CoA carboxylase inhibitor.</p>Formula:C29H33N3O8SColore e forma:SolidPeso molecolare:583.65Ambelline
CAS:<p>Ambelline has antitumor activity.</p>Formula:C18H21NO5Purezza:98%Colore e forma:SolidPeso molecolare:331.36Trk-IN-7
<p>Trk-IN-7 inhibits TRKA/B/C (IC50: 0.25-10 nM) & EML4-ALK (<15 nM), also targets various ALK mutations (IC50: 5-50 nM).</p>Formula:C18H17FN6O2Colore e forma:SolidPeso molecolare:368.36CVT-5440
CAS:<p>CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.</p>Formula:C27H28N6O5Colore e forma:SolidPeso molecolare:516.55TRPA1 Antagonist 1
CAS:<p>TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.</p>Formula:C24H20F6N5Na2O7PSPurezza:98%Colore e forma:SolidPeso molecolare:713.45CB-7646
CAS:<p>CB-7646 is a stable trimelamol (TM) analogue, which is an antitumor agent.</p>Formula:C8H16N6O2Colore e forma:SolidPeso molecolare:228.25SBI-581
<p>SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.</p>Formula:C24H21N3O2Colore e forma:SolidPeso molecolare:383.44γ-secretase modulator 5
<p>Compound 22d is a GSM that crosses the blood-brain barrier, inhibits Aβ42 production (IC50: 60 nM), and may help study Alzheimer's.</p>Colore e forma:SolidTGFβ1-IN-1
CAS:<p>TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.</p>Formula:C22H24N2O3Purezza:99.89% - 99.89%Colore e forma:SolidPeso molecolare:364.438Nipradolol
CAS:<p>Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.</p>Formula:C15H22N2O6Colore e forma:SolidPeso molecolare:326.35FLT3-IN-13
<p>FLT3-IN-13 inhibits topoisomerase II/FLT3 in leukemia with IC50 of 2.26 μM, causes G2/M arrest, and promotes apoptosis.</p>Formula:C20H14N4O2Colore e forma:SolidPeso molecolare:342.35Teoprolol
CAS:<p>Teoprolol is a blocker of β-adrenergic receptor.</p>Formula:C23H30N6O4Purezza:98%Colore e forma:SolidPeso molecolare:454.52MCTR2
CAS:<p>MCTR2, synthesized from DHA in macrophages, aids in tissue repair and reduces inflammation by promoting eicosanoid PGD2 and PGF2α decrease.</p>Formula:C27H40N2O6SColore e forma:SolidPeso molecolare:520.6813(R)-HODE
CAS:<p>13(R)-HODE, produced from linoleic acid, inhibits platelet aggregation (IC50=2.7μM) and is found in bovine endothelial cells.</p>Formula:C18H32O3Colore e forma:SolidPeso molecolare:296.44SMP-797 HCl
CAS:<p>SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.</p>Formula:C34H44ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:622.20Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Formula:C18H27N3O2S3Colore e forma:SolidPeso molecolare:413.62Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Formula:C17H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.81KFA1982
CAS:<p>KFA1982 is a novel and potent factor Xa inhibitor.</p>Formula:C28H34ClN3O9S2Colore e forma:SolidPeso molecolare:656.17Antitumor agent-54
<p>Compound C11 inhibits 14-3-3η protein (KD: 35 μM), targets liver cancer cells, blocks G1-S phase, and induces apoptosis.</p>Formula:C29H32N2O3Colore e forma:SolidPeso molecolare:456.58MRS2179 tetrasodium hydrate
<p>MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.</p>Formula:C11H15N5Na4O10P2Colore e forma:SolidPeso molecolare:576.21Notch inhibitor 1
CAS:<p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>Formula:C26H25F7N4O3Purezza:98%Colore e forma:SolidPeso molecolare:574.49DLK-IN-1
CAS:DLK-IN-1: Oral DLK (MAP3K12) inhibitor, Ki=3nM, effective in Alzheimer's model, CNS permeable, well-tolerated with sustained brain levels.Formula:C20H24F3N5O2Colore e forma:SolidPeso molecolare:423.43Antibacterial agent 110
<p>Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).</p>Formula:C22H21N5O4SColore e forma:SolidPeso molecolare:451.5Isobetanin
CAS:<p>Isobetanin is a betacyanin that has been shown to enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells.</p>Formula:C24H26N2O13Colore e forma:SolidPeso molecolare:550.47Isoleucyl tRNA synthetase-IN-1
CAS:<p>Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).</p>Formula:C23H35N5O7SColore e forma:SolidPeso molecolare:525.62Antitumor agent-72
CAS:<p>Antitumor agent-72 (compound 6w) is a potent anticancer agent that exhibits its anticancer activity by inducing apoptosis via caspase-3 activation and PARP</p>Formula:C25H20ClNO6Colore e forma:SolidPeso molecolare:465.88MSA-2 dimer
CAS:<p>MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.</p>Formula:C29H28O8S2Colore e forma:SolidPeso molecolare:568.66Dictyostatin
CAS:<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Formula:C32H52O6Colore e forma:SolidPeso molecolare:532.75rel-MDM2/4-p53-IN-2
<p>Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.</p>Formula:C25H17Cl3FN3O3Colore e forma:SolidPeso molecolare:532.78Terguride
CAS:<p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>Formula:C20H28N4OColore e forma:SolidPeso molecolare:340.46CXCR4 probe 1
CAS:<p>CXCR4 probe 1, a specific PET tracer, targets CXCR4 with antagonist TN14003 (IC50: 6.9 nM), aiding in imaging CXCR4-related diseases and tumors.</p>Formula:C24H30FN5O4SColore e forma:SolidPeso molecolare:502.59NF-κB-IN-4
<p>NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB).</p>Formula:C18H15FN4OColore e forma:SolidPeso molecolare:322.34Bomedemstat hydrochloride
<p>Bomedemstat (IMG-7289) hydrochloride, an oral LSD1 inhibitor, has anticancer properties, blocking cell growth and triggering apoptosis.</p>Formula:C28H35ClFN7O2Colore e forma:SolidPeso molecolare:556.08IDO1-IN-13
<p>IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.</p>Formula:C20H16BrN5O2SColore e forma:SolidPeso molecolare:470.34AKR1C3-IN-7
<p>AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.</p>Formula:C24H20N2O4Colore e forma:SolidPeso molecolare:400.43TP003
CAS:<p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>Formula:C23H16F3N3OPurezza:99.17%Colore e forma:SolidPeso molecolare:407.39L-Moses dihydrochloride
<p>L-Moses (L-45) dihydrochloride is the first, potent, selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor (Kd: 126 nM).</p>Formula:C21H26Cl2N6Colore e forma:SolidPeso molecolare:433.38BRD50837
CAS:<p>BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).</p>Formula:C26H32ClN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:550.07PCSK9-IN-17
CAS:<p>PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.</p>Formula:C16H19N5OSColore e forma:SolidPeso molecolare:329.42SCP1-IN-1
CAS:<p>SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.</p>Formula:C20H19F3N2O7S2Purezza:99.53%Colore e forma:SoildPeso molecolare:520.5AXKO-0046
<p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>Formula:C25H33N3Colore e forma:SolidPeso molecolare:375.55ND-2158
CAS:<p>ND-2158 is a potent and selective inhibitor of IRAK4.</p>Formula:C22H30N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:446.56NLRP3-IN-6
<p>NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.</p>Formula:C18H15ClN2O4S3Colore e forma:SolidPeso molecolare:454.97Acetoxycycloheximide
CAS:<p>Acetoxycycloheximide triggers TNF receptor 1, prompts apoptosis, and cytochrome c release by activating c-Jun N-terminal kinase.</p>Formula:C17H25NO6Colore e forma:SolidPeso molecolare:339.38MsbA-IN-3
<p>MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).</p>Formula:C24H22Cl2N2O4SColore e forma:SolidPeso molecolare:505.41RSK4-IN-1
CAS:<p>RSK4-IN-1 is a compound exhibiting potent inhibition of RSK4, demonstrated by an IC50 value of 9.5 nM.</p>Formula:C19H20F2N4O3Colore e forma:SolidPeso molecolare:390.38AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Formula:C32H35ClN6O3Colore e forma:SolidPeso molecolare:587.11Norbinaltorphimine dihydrochloride
CAS:<p>Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.</p>Formula:C40H45Cl2N3O6Purezza:98.17% - 99.88%Colore e forma:SolidPeso molecolare:734.71IRAK4-IN-12
<p>IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 (IC50: 0.015 μM) with cellular pIRAK4 potency (IC50: 0.5 μM).</p>Formula:C24H31FN8OColore e forma:SolidPeso molecolare:466.55MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Formula:C26H35FN16O2Purezza:98%Colore e forma:SolidPeso molecolare:622.66GSK-3036656 free base
CAS:<p>GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.</p>Formula:C10H13BClNO4Colore e forma:SolidPeso molecolare:257.48Ro 24-4383
CAS:<p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>Formula:C32H31FN8O10S2Purezza:98%Colore e forma:SolidPeso molecolare:770.76MI-1851
CAS:<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Formula:C34H53N15O6Colore e forma:SolidPeso molecolare:767.88MK-8970
<p>MK-8970 is an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.</p>Formula:C25H29FN6O8Colore e forma:SolidPeso molecolare:560.54TAK-828F
CAS:<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Formula:C28H32FN3O5Purezza:98%Colore e forma:SolidPeso molecolare:509.57Aeroplysinin 1
CAS:<p>Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation.</p>Formula:C9H9Br2NO3Colore e forma:SolidPeso molecolare:338.98MDK-3298
CAS:<p>MDK-3298 is a reversible covalent inhibitor of Mcl-1, a target of protein-protein interaction (PPI).</p>Formula:C35H32BN3O7Purezza:98%Colore e forma:SolidPeso molecolare:617.46PqsR-IN-1
<p>PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.</p>Formula:C17H18ClN3OSColore e forma:SolidPeso molecolare:347.86PTP1B-IN-21
<p>PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.</p>Formula:C22H22O11Colore e forma:SolidPeso molecolare:462.4PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Formula:C16H27N5O3SColore e forma:SolidPeso molecolare:369.48CAII-IN-1
<p>CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.</p>Formula:C19H21FN4SColore e forma:SolidPeso molecolare:356.46NTPDase-IN-3
CAS:<p>NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.</p>Formula:C22H24ClN3OS2Colore e forma:SolidPeso molecolare:446.03KIRA9
<p>KIRA9 inhibits IRE1 with a 4.8 μM IC50, blocking ER-stress-induced mRNA decay and apoptosis by fully binding IRE1's ATP site.</p>Formula:C27H27F3N6O3SColore e forma:SolidPeso molecolare:572.6ATR-IN-12
<p>ATR-IN-12, a potent ATR kinase inhibitor with IC50 of 0.007 μM, shows promise for drug development.</p>Formula:C22H27N5O3SColore e forma:SolidPeso molecolare:441.55Thiolactomycin
CAS:<p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>Formula:C11H14O2SPurezza:98%Colore e forma:SolidPeso molecolare:210.29(±)-J 113397
CAS:<p>(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).</p>Formula:C24H37N3O2Colore e forma:SolidPeso molecolare:399.57IMP-321
CAS:<p>IMP-321 is a soluble dimeric recombinant form of LAG-3 and first-in-class antigen presenting cell activator.</p>Formula:C56H78N18O14SColore e forma:SolidPeso molecolare:1259.4BET-IN-1
<p>BET-IN-1 is a potent inhibitor of BET, exhibiting good brain permeability and a reasonable metabolic stability.</p>Formula:C23H24ClFN4O3SColore e forma:SolidPeso molecolare:490.98
