Inibitori
Gli inibitori sono molecole che si legano a enzimi, recettori o altre proteine per ridurre o bloccare la loro attività biologica. Questi composti sono ampiamente utilizzati nella ricerca per studiare le vie biologiche, comprendere i meccanismi delle malattie e sviluppare farmaci terapeutici. Gli inibitori svolgono un ruolo cruciale nel trattamento di varie malattie, tra cui il cancro, le malattie cardiovascolari e le infezioni. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità per supportare le tue ricerche in biochimica, biologia cellulare e sviluppo farmaceutico.
Sottocategorie di "Inibitori"
- Angiogenesi(2.524 prodotti)
- Apoptosi(5.793 prodotti)
- Ciclo cellulare/Checkpoint(4.452 prodotti)
- Cromatina/Epigenetica(2.242 prodotti)
- Segnalazione citoscheletrica(1.382 prodotti)
- Danno al DNA/Riparazione del DNA(2.826 prodotti)
- Endocrinologia/Ormoni(3.507 prodotti)
- Enzima(3.640 prodotti)
- Proteina G/GPCR(8.333 prodotti)
- Immunologia e infiammazione(3.527 prodotti)
- Virus dell'influenza(296 prodotti)
- Segnalazione JAK/STAT(404 prodotti)
- Segnalazione MAPK(1.203 prodotti)
- Trasportatore di membrana/canale ionico(2.792 prodotti)
- Metabolismo(9.449 prodotti)
- Microbiologia/Virologia(6.981 prodotti)
- Neuroscienza(9.926 prodotti)
- Altri inibitori(37.921 prodotti)
- Ossidazione-riduzione(41 prodotti)
- Segnalazione PI3K/Akt/mTOR(1.400 prodotti)
- Proteasi/Proteasoma(1.597 prodotti)
- Cellule staminali e Derivati(830 prodotti)
- Adattatori Tirosin-chinasi(2.015 prodotti)
- Ubiquitinazione(1.650 prodotti)
Mostrare 16 più sottocategorie
Trovati 66639 prodotti di "Inibitori"
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Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan
CAS:<p>Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a linker molecule employed in the synthesis of antibody-drug conjugates (ADCs), demonstrating potent antitumor</p>Formula:C55H60FN9O13Colore e forma:SolidPeso molecolare:1074.12PI3Kδ-IN-13
CAS:<p>PI3Kδ-IN-13 (compound 89), with an IC50 value of 2.6 nM, is an inhibitor of PI3Kδ, applicable for researching diseases involving cell proliferation, including</p>Formula:C27H39N7O4S2Colore e forma:SolidPeso molecolare:589.77JAK1-IN-10
CAS:<p>JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].</p>Formula:C15H17N7Purezza:98%Colore e forma:SolidPeso molecolare:295.34(αR)-Cyclopropaneacetamide-Exatecan
CAS:<p>(αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, serves as a cytotoxic agent that effectively inhibits the proliferation of U87MG</p>Formula:C29H28FN3O6Colore e forma:SolidPeso molecolare:533.55Tauro-Obeticholic Acid sodium
CAS:<p>Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid.</p>Formula:C28H48NO6S·NaColore e forma:SolidPeso molecolare:549.74JDB175
CAS:<p>JDB175, a selective BTK inhibitor with oral bioavailability, demonstrates excellent penetration through the blood-brain barrier.</p>Formula:C26H21F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:478.47BTK-IN-25
CAS:<p>BTK-IN-25 (compound 71) is a potent BTK inhibitor, demonstrating an IC50 of 0.77 nM against BTK(C481S) and achieving an IC50 of 1 nM in DOHH2 cells [1].</p>Formula:C28H27F2N3O5Purezza:98%Colore e forma:SolidPeso molecolare:523.53RIOK2-IN-2
CAS:<p>RIOK2-IN-2 (8) functions as an inhibitor of RIOK2, exhibiting IC50 values of 3.02 μM in MKN-1 cells and 5.34 μM in MOLT4 cells [1].</p>Formula:C27H23F3N6O2Colore e forma:SolidPeso molecolare:520.51DiaFluo
CAS:<p>DiaFluo is a probe for protein S-sulfinylation from cells.</p>Formula:C32H32N4O9SColore e forma:SolidPeso molecolare:648.69LT-540-717
CAS:<p>LT-540-717 (compound 32), a potent FLT3 inhibitor (IC50=0.62 nM), exhibits antiproliferative activity and effectively inhibits various acquired FLT3 mutations,</p>Formula:C24H24N8O2Colore e forma:SolidPeso molecolare:456.5Ref: TM-T79490
Prodotto fuori produzioneSHP2-IN-14
CAS:<p>SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM.</p>Formula:C22H20Cl2N8OColore e forma:SolidPeso molecolare:483.35Ref: TM-T79108
Prodotto fuori produzioneI5B2
CAS:<p>I5B2 is a novel phosphorus-containing angiotensin I converting enzyme inhibitor. Angiotensin I converting enzyme is produced by Actinomadura sp.</p>Formula:C23H32N3O7PPurezza:98%Colore e forma:SolidPeso molecolare:493.49Ref: TM-T25515
Prodotto fuori produzioneAnd1-IN-1
CAS:<p>And1-IN-1, also known as compound III, is a potent inhibitor of And1 [1].</p>Formula:C15H11BCl2O2Colore e forma:SolidPeso molecolare:304.96MDL-811
CAS:<p>MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),</p>Formula:C25H25BrCl2FN3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:681.42FLT3-IN-19
CAS:<p>FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute</p>Formula:C22H26N8OColore e forma:SolidPeso molecolare:418.49diMal-O-CH2COOH
CAS:<p>DiMal-O-CH2COOH is a cleavable linker utilized in antibody-drug conjugates (ADCs).</p>Formula:C13H12N2O7Colore e forma:SolidPeso molecolare:308.24STAT3-IN-18
CAS:<p>STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and</p>Formula:C18H24Cl2N2O6PtPurezza:98%Colore e forma:SolidPeso molecolare:630.38BCR-ABL-IN-8
CAS:<p>BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].</p>Formula:C30H33N7O5Purezza:98%Colore e forma:SolidPeso molecolare:571.63Py-MAA-Val-Cit-PAB-MMAE
CAS:<p>Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties.</p>Formula:C72H111N13O16SColore e forma:SolidPeso molecolare:1446.79APG-2449
CAS:<p>APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in mouse models of non-small cell lung cancer (NSCLC) [1].</p>Formula:C33H42ClN5O4SPurezza:98%Colore e forma:SolidPeso molecolare:640.24Ref: TM-T79363
Prodotto fuori produzioneSakura 6
CAS:<p>Sakura 6, a synthetic serotonin transporter (SERT)-binding peptide, enhances the interaction between SERT and neuronal nitric oxide synthase.</p>Formula:C31H45N5O7Colore e forma:SolidPeso molecolare:599.73Mal-VC-PAB-PNP-CDN-A
CAS:<p>Mal-VC-PAB-PNP-CDN-A is a conjugate comprised of an agent and a linker, utilized in antibody-drug conjugates (ADC) [1] [2].</p>Formula:C51H67N17O20P2Colore e forma:SolidPeso molecolare:1300.13Tibremciclib
CAS:<p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>Formula:C28H32F2N8Purezza:98%Colore e forma:SolidPeso molecolare:518.6Bumetanide sodium
CAS:<p>Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).</p>Formula:C17H19N2NaO5SColore e forma:SolidPeso molecolare:386.4Ref: TM-T61713
Prodotto fuori produzioneLM2I
CAS:<p>LM2I, a derivative of Spinosyn A (SPA), serves both as an argininosuccinate synthase (ASS1) enzyme activator and a tumor inhibitor through direct interaction</p>Formula:C47H77N3O11Colore e forma:SolidPeso molecolare:860.13BBDDL2059
CAS:<p>BBDDL2059 is a selective covalent inhibitor targeting EZH2, exhibiting an IC50 of 1.5 nM against the EZH2-Y641F mutant.</p>Formula:C27H36N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:512.66Ref: TM-T79200
Prodotto fuori produzioneALPK1-IN-3
CAS:<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Formula:C20H16F2N4OSPurezza:98%Colore e forma:SolidPeso molecolare:398.43DDO-2213
CAS:<p>DDO-2213 is a potent, orally active inhibitor of the WDR5-MLL1 interaction, demonstrating an IC50 of 29 nM and a Kd of 72.9 nM against WDR5.</p>Formula:C24H27ClFN7OColore e forma:SolidPeso molecolare:483.97DPP
CAS:<p>DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating</p>Formula:C36H40Cl2N2O10PtPurezza:98%Colore e forma:SolidPeso molecolare:926.7PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Formula:C19H19FN4O2SPurezza:99.4%Colore e forma:SolidPeso molecolare:386.44Ifetroban
CAS:<p>Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.</p>Formula:C25H32N2O5Colore e forma:SolidPeso molecolare:440.53Ref: TM-T27588
Prodotto fuori produzioneALS-I-41
CAS:<p>ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.</p>Formula:C30H38FN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:587.7Ref: TM-T26602
Prodotto fuori produzioneDG026
CAS:<p>DG026 selectively inhibits IRAP, reducing its cross-presentation in dendritic cells without affecting ERAP1.</p>Formula:C35H40N3O4PPurezza:98%Colore e forma:SolidPeso molecolare:597.68Ref: TM-T27160
Prodotto fuori produzioneDimethandrolone Undecanoate
CAS:<p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>Formula:C31H50O3Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:470.73Ref: TM-T27176
Prodotto fuori produzioneIfetroban sodium
CAS:<p>Ifetroban sodium (BMS-180291), oral TXA2/PGH2 antagonist for researching heart, stroke, BP, thrombosis.</p>Formula:C25H31N2NaO5Colore e forma:SolidPeso molecolare:462.522Ref: TM-T62924
Prodotto fuori produzioneBPH-628
CAS:<p>BPH-628 is a bioactive chemical.</p>Formula:C20H20O7P2Colore e forma:SolidPeso molecolare:434.32ROCK-IN-6
CAS:<p>ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1</p>Formula:C19H19N5O8SPurezza:98%Colore e forma:SolidPeso molecolare:477.45Ref: TM-T79077
Prodotto fuori produzioneCortivazol
CAS:<p>Cortivazol is an Anti-Inflammatory Drug.</p>Formula:C32H38N2O5Purezza:98%Colore e forma:SolidPeso molecolare:530.65Ref: TM-T25271
Prodotto fuori produzionehDHODH-IN-8
<p>hDHODH-IN-8 is a potent human dihydroorotic dehydrogenase (hDHODH) inhibitor (IC50: 16 nM) that exhibits potent antiproliferative effects and has good water solubility, with potential for oncology studies, especially in lymphoma.</p>Formula:C21H15F6N3O4Purezza:98%Peso molecolare:487.35
