Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8901 prodotti di "Derivati delle Purine e Pirimidine"
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5-((tert-Butoxycarbonyl)amino)pyrimidine-2-carboxylic acid
CAS:Purezza:95%Peso molecolare:239.2310028076172N-Methyl Pemetrexed
CAS:Prodotto controllato<p>Impurity Pemetrexed EP Impurity A<br>Applications N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.<br>References Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005);<br></p>Formula:C21H23N5O6Colore e forma:NeatPeso molecolare:441.446-Hydroxy Ondansetron
CAS:<p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>Formula:C18H19N3O2Colore e forma:Off-White To Light BrownPeso molecolare:309.362Tenofovir Monoisoproxil Dimer Ammonium Sodium Salt (>85%)
Prodotto controllato<p>Stability Light Sensitive, Temperature Sensitive, Very Hygroscopic<br>Applications Tenofovir Monoisoproxil Dimer Ammonium Sodium Salt is an impurity in the synthesis of Tenofovir disoproxil (T018505),an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor.<br>References Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C29H42N10O14P2•x(Na)•x(NH3)Purezza:>85%Colore e forma:NeatPeso molecolare:816.65 + x(22.99) + x(17.03)Methotrexate-Cadaverine-Biotin Conjugate
Prodotto controllato<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C35H48N12O6SPurezza:>85%Colore e forma:NeatPeso molecolare:764.9MOC-POC Tenofovir Fumarate Salt (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formula:C17H26N5O10P·C4H4O4Colore e forma:White To Off-WhitePeso molecolare:607.464-([1,1'-Biphenyl]-4-yl)-6-chloro-2-phenylpyrimidine
CAS:Purezza:95.0%Peso molecolare:342.8299865722656Ref: 10-F053935
1gPrezzo su richiesta5gPrezzo su richiesta25gPrezzo su richiesta250mgPrezzo su richiesta4,5,6-Trifluoro-2-trifluoromethyl-pyrimidine
CAS:Formula:C5F6N2Colore e forma:LiquidPeso molecolare:202.059Ref: 10-F099268
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta25gPrezzo su richiesta100mg91,00€200mgPrezzo su richiestaTenofovir Alafenamide Fumarate
CAS:Prodotto controllato<p>Applications Tenofovir Alafenamide Fumarate is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C21H29N6O5P·C4H4O4Colore e forma:NeatPeso molecolare:592.5381(S)-Tenofovir Disoproxil Fumarate
CAS:Prodotto controllato<p>Impurity Tenofovir Disoproxil USP Related Compound A<br>Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.<br>References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C19H30N5O10P·C4H4O4Colore e forma:White SolidPeso molecolare:635.522-CHLORO-N-(4-CHLOROPHENYL)-9-METHYL-9H-PURIN-6-AMINE
CAS:Purezza:95.0%Peso molecolare:294.14001464843754-(2-fluorophenyl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:255.2519989013672Nicotinic Acid-13C1 (~1% unlabeled)
CAS:<p>Applications Isotope labelled analogue of Nicotinic Acid (N429250), also known as vitamin B3, is an essential nutrient that must be obtained from a dietary source in order for normal body function. The administration of Nicotinic Acid in animal models of ischemia was shown to significantly reduce the size of infarction and improve functional recovery. Current findings suggest that nicotinic acid may have therapeutic potential for the treatment of traumatic brain injury.<br>References Xu, P., et al.: Mech Age. Dev., 4, 287 (2010); Hoane, M.R., et al.: J. Neurotrauma, 20, 1189 (2003);<br></p>Formula:C513CH5NO2Colore e forma:NeatPeso molecolare:124.1N6-(2-Isopentenyl)adenine
CAS:Prodotto controllato<p>Applications N6-(2-Isopentenyl)adenine can be used in biological study for cytokinins stimulated expression of stress-related proteins and transcripts in Arabidopsis thaliana with isopentenyltransferase overexpression.<br>References Skalak, J., et al.: J. Exp. Bot., 67, 2861-2873 (2016)<br></p>Formula:C10H13N5Colore e forma:White To Off-WhitePeso molecolare:203.24Methotrexate
CAS:<p>Stability Hygroscopic<br>Applications A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C20H22N8O5Colore e forma:Yellow To Dark YellowPeso molecolare:454.44N2-ISOBUTYRYL-2'-O-METHYL-GUANOSINE
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:367.36199951171875N-(2-Chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:287.75Ref: 10-F216838
1gPrezzo su richiesta5g105,00€10g194,00€25g347,00€100g893,00€250mgPrezzo su richiestaPorphobilinogen
CAS:Prodotto controllato<p>Applications An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.<br>References Westall, et al.: Nature, 170, 614 (1952), Cookson, R., et al.: Biochem, J., 57, 476 (1954), MacDonald, J., Can. J. Chem., 35, 715 (1957),<br></p>Formula:C10H14N2O4Colore e forma:NeatPeso molecolare:226.231-(4-((6-CHLORO-2-METHYLPYRIMIDIN-4-YL)AMINO)-3-FLUOROPHENYL)-3-(4-FLUOROPHENYL)UREA
Purezza:95.0%Peso molecolare:389.79000854492193-Nitro-L-tyrosine-d3
CAS:Prodotto controllato<p>Applications A labelled marker for peroxynitrite. Oxidant and cytotoxic agent.<br>References Sekiguchi, M., et al.: Brain Res., 978, 228 (2003), van den Tweel, E., et al.: J. Neurobiol., 167, 64 (2005), Shirakura, T., et al.: Biol. Pharm. Bull., 28, 1658 (2005),<br></p>Formula:C9D3H7N2O5Colore e forma:NeatPeso molecolare:229.24-(3,4-dimethylphenyl)-6-(4-fluorophenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:293.34500122070313-Methyl-1H-purine-2,6(3H,7H)-dione
CAS:Formula:C6H6N4O2Purezza:95%Colore e forma:Solid, Light yellow powderPeso molecolare:166.144-(3-Ethylureido)-2-methylbenzenesulfonyl chloride
CAS:Formula:C10H13ClN2O3SColore e forma:SolidPeso molecolare:276.744-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester
CAS:Prodotto controllato<p>Applications Intermediate in the preparation of Pemetrexed.<br></p>Formula:C19H17N5O5Colore e forma:WhitePeso molecolare:395.37N,N'-Di-Boc-guanidine
CAS:Purezza:99.0%Colore e forma:Solid, Crystalline Powder or PowderPeso molecolare:259.30599975585944-(furan-2-yl)-6-(5-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:257.30999755859375Methotrexate Diglutamate Trifluoroacetate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Methotrexate Diglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C25H29N9O8xC2HF3O2Colore e forma:NeatPeso molecolare:583.55L-Aspartyl-L-phenylalanine Hydrochloride
CAS:Prodotto controllato<p>Applications L-Aspartyl-L-phenylalanine is an impurity of Thiamine (T344185). Thiamine Impurity B.<br>References Aluwihare, L., et al.: Science, 308, 1007 (2005), Koch, B., et al.: Anal. Chem., 79, 1758 (2007), Reemtsma, T., et al.: Environ. Sci. Technol., 42, 1430 (2008),<br></p>Formula:C13H16N2O5xHClColore e forma:NeatPeso molecolare:280.284,6-Dihydroxypyrazolo[3,4-d]pyrimidine
CAS:Prodotto controllato<p>Stability Hygroscoipic<br>Applications 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a major metabolite of Allopurinol (A547300). It is a xanthine oxidase inhibitor.<br>References Pacher, P., et al.: Pharmacol. Rev., 58, 87 (2006); Marro, P., et al.: Brain Res., 650, 9 (1994); Abramov, A., et al.: J. Neurosci., 27, 1129 (2007); Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007);<br></p>Formula:C5H4N4O2Colore e forma:Off White SolidPeso molecolare:152.113-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile
CAS:Purezza:98.0%Peso molecolare:426.4840087890625Ref: 10-F546540
5mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta3-Amino-4-carbamoylpyrazole Hemisulfate
CAS:Prodotto controllato<p>Impurity Allopurinol EP Impurity A / Allopurinol USP Related Compound A<br>Stability Hygroscopic<br>Applications 3-Amino-4-carbamoylpyrazole Hemisulfate (Allopurinol EP Impurity A) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975);<br></p>Formula:C4H6N4O·H2O4SColore e forma:White To Light BrownPeso molecolare:350.31[1-(2-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-amine hydrochloride
CAS:Purezza:95.0%Peso molecolare:263.1700134277344N4-BENZYL-N2-(4-BROMOPHENYL)-5-FLUOROPYRIMIDINE-2,4-DIAMINE
Purezza:95.0%Peso molecolare:373.22900390625Nicotinic Acid-d3 (major)
CAS:Prodotto controllato<p>Applications Labelled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term “niacin” has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor).A representative lot contains >20% d4.<br>References Darby, W.J., et al.: Nutr. Rev., 33, 289 (1975), Black, A., et al.: Eur. J. Clin. Nutr., 54, 395 (2000), Cole, T., et al.: Br. Med. J., 320, 1240 (2000), Forshee, R., et al.: J. Nutr., 134, 2733 (2004),<br></p>Formula:C6H2D3NO2Colore e forma:NeatPeso molecolare:126.133,5-Dimethyl-1-adamantanol
CAS:Prodotto controllato<p>Impurity Memantine USP Related Compound B (3,5-Dimethyladamantane-1-ol)<br>Applications 3,5-Dimethyl-1-adamantanol is an impurity of Memantine (M218000). Memantine impurity B. Memantine USP Related Compound B (3,5-Dimethyladamantane-1-ol).<br>References England, P., et al.: Biochemistry, 43, 11623 (2004), Schousboe, A., et al.: Eur. J. Pharmacol., 500, 281 (2004), Horvat, S., et al.: J. Med. Chem., 49, 3136 (2006),<br></p>Formula:C12H20OColore e forma:WhitePeso molecolare:180.294-(3-fluorophenyl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:255.25199890136726-[(E)-4-Hydroxy-3-methylbut-2-enylamino]-9-β-D-ribofuranosylpurine
CAS:Prodotto controllato<p>Applications A well-known, highly active stimulant of cell divisions in plant tissue cultures.<br>References D.S. Letham: Phytochemistry, 12, 2445 (1973)<br></p>Formula:C15H21N5O5Colore e forma:NeatPeso molecolare:351.36Theophylline-d6
CAS:Prodotto controllato<p>Applications Xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975), Svedmyr, K., et al.: Allergy, 37, 111 (1982),<br></p>Formula:C72H6H2N4O2Colore e forma:White To Off-WhitePeso molecolare:186.206-Methylpurine
CAS:Purezza:95.0%Colore e forma:Solid, Light yellow solidPeso molecolare:134.14199829101562Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate
CAS:Purezza:95.0%Colore e forma:Liquid, No data available.Peso molecolare:296.32998657226566-METHYL-N1-(3-METHYL-1-(6-(METHYLAMINO)PYRIMIDIN-4-YL)-1H-PYRAZOL-5-YL)BENZENE-1,3-DIAMINE
CAS:Purezza:95.0%Peso molecolare:309.37701416015625Iopamidol-D3
CAS:Prodotto controllato<p>Applications Labelled nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).<br>References Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982), Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982), Sovak, M., et al.: Radiology, 142, 115 (1982), Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988),<br></p>Formula:C17H19D3I3N3O8Colore e forma:Off-WhitePeso molecolare:780.103-(Formylamino)-1H-pyrazole-4-carboxamide
CAS:Prodotto controllato<p>Impurity Allopurinol EP Impurity B / Allopurinol USP Related Compound B<br>Stability Hygroscopic<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxamide (Allopurinol EP Impurity B) is an impurity of Allopurinol (A547300) with inhibitory effects on human hypoxanthine phosphoribosyltransferase.<br>References Krenitzky, T.A. et al.: J. Biol. Chem., 244, 1263 (1969);<br></p>Formula:C5H6N4O2Colore e forma:White To Off-WhitePeso molecolare:154.127(2R,3R,4R,5R)-2-(2-AMINO-9H-PURIN-9-YL)-5-(HYDROXYMETHYL)-3-METHYLTETRAHYDROFURAN-3,4-DIOL
CAS:Purezza:95.0%Peso molecolare:281.27200317382811,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS:Prodotto controllato<p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>Formula:C17H17N3OColore e forma:White To Off-WhitePeso molecolare:279.34Orotic Acid-15N2 Monohydrate
CAS:<p>Applications Orotic Acid-15N2 Monohydrate is a labelled analogue of Orotic Acid Monohydrate (O691500(P)), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br>References Furukawa, S.: PCT Int. Appl. (2009), WO 2009069291 A1<br></p>Formula:C5H415N2O4·H2OColore e forma:NeatPeso molecolare:177.09N-(4-Fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide
CAS:Purezza:97.0%Peso molecolare:536.168282748Ref: 10-F546272
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiestaMethotrexate a-Methyl Ester (>90%)
CAS:Prodotto controllato<p>Impurity Methotrexate EP Impurity I<br>Applications Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C21H24N8O5Purezza:>90%Colore e forma:NeatPeso molecolare:468.472,4,5,6-Tetraaminopyrimidine Sulfate
CAS:Prodotto controllato<p>Applications Intermediate in the production of Methotrexate<br>References Chiosis, G., et al.: Bioorg. Med. Chem., 10, 3555 (2002), Palanki, M., et al.: J. Med. Chem., 50, 4279 (2007), Zav'yalov, S., et al.: Pharm. Chem. J., 42, 51 (2008),<br></p>Formula:C4H8N6·H2O4SColore e forma:NeatPeso molecolare:238.22L-Monapterin
CAS:Prodotto controllato<p>Applications L-Monapterin is the major pterin compound extracted from Escherichia coli (E.coli) and is used in its detection and identification.<br>References Sugimoto, T. et al.: Hetero., 54, 283 (2001); Ikawa, M. et al.: Phytochem., 38, 1229 (1995);<br></p>Formula:C9H11N5O4Colore e forma:Light OrangePeso molecolare:253.21Ref: 10-F494511
1gPrezzo su richiesta2.5gPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta2-[(2-Amino-6-chloro-4-pyrimidinyl)amino]ethanol
CAS:Purezza:95.0%Colore e forma:Solid, Yellow powderPeso molecolare:188.61999511718755-METHOXY-4-((4-(1-METHYL-1H-INDOL-3-YL)PYRIMIDIN-2-YL)AMINO)-2-NITROPHENOL
Purezza:95.0%Peso molecolare:391.3869934082031Tenofovir Disoproxil Isopropoxycarbonyl
CAS:<p>Stability Hygroscopic<br>Applications Tenofovir Disoproxil derivative as antiviral and antitumor agent.<br></p>Formula:C23H36N5O12PColore e forma:White SolidPeso molecolare:605.53Methotrexate-d3
CAS:Prodotto controllato<p>Applications Labelled Methotrexate (M260675). A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C20H19D3N8O5Colore e forma:NeatPeso molecolare:457.46(S)-4-(2,4-Difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine
CAS:Purezza:95.0%Peso molecolare:320.35998535156251,7-Dimethyluric Acid
CAS:Prodotto controllato<p>Applications A metabolite of Caffeine.<br>References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),<br></p>Formula:C7H8N4O3Colore e forma:NeatPeso molecolare:196.16N'-Methyl-N,N-diphenylurea
CAS:<p>Impurity Temozolomide USP Related Compound B<br>Applications N'-Methyl-N,N-diphenylurea is used in the stabilization of thermal propellants. Temozolomide USP Related Compound B.<br>References Bohn, M. et al.: Prop. Exp. Pyro.,et al.: 19, 266 (1994); Muthurajan, H. et al.: J. Hazard. Mat., 133, 30 (2006);<br></p>Formula:C14H14N2OColore e forma:NeatPeso molecolare:226.278-Descarboxamido-8-cyano Temozolomide
CAS:Prodotto controllato<p>Applications 8-Descarboxamido-8-cyano Temozolomide is a useful synthetic intermediate in the synthesis of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)<br></p>Formula:C6H4N6OColore e forma:Light Yellow To Light BrownPeso molecolare:176.146-CHLORO-1-(4-METHOXYBENZYL)-3-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
CAS:Purezza:95.0%Peso molecolare:280.7099914550781Ref: 10-F506034
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiestaChloromethyl Propyl Carbonate
CAS:Prodotto controllato<p>Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.<br></p>Formula:C5H9ClO3Colore e forma:Colourless OilyPeso molecolare:152.584-(4-tert-butylphenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:309.429992675781253,5,3',5'-Tetraiodo Thyrolactic Acid (~90%)
CAS:Prodotto controllato<p>Stability Hygroscopic, Temperature sensitive<br>Applications 3,5,3',5'-Tetraiodo Thyrolactic Acid is a thyroid hormone analogue. A Thyroxine (T425600) analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989); Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992); Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999); Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002);<br></p>Formula:C15H10I4O5Purezza:~90%Colore e forma:BeigePeso molecolare:777.85Thyroxine
CAS:Prodotto controllato<p>Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.<br>References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);<br></p>Formula:C15H11I4NO4Colore e forma:Off-WhitePeso molecolare:776.87Ref: 10-F531105
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta6-Methylpurine
CAS:Prodotto controllato<p>Applications 6-Methylpurine (cas# 2004-03-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C6H6N4Colore e forma:NeatPeso molecolare:134.142-Fluoroadenosine
CAS:Prodotto controllato<p>Applications 2-Fluoroadenosine is a fluorinated analog of Adenoside (A280400) nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>Formula:C10H12FN5O4Colore e forma:NeatPeso molecolare:285.23Methotrexate-d3 Hexaglutamate Trifluoroacetic Acid Salt
CAS:Prodotto controllato<p>Applications Methotrexate-d3 Hexaglutamate is the isotope labelled analog of Methotrexate Hexaglutamate (M260745); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C45H54D3N13O20•x(C2HF3O2)Colore e forma:NeatPeso molecolare:1103.0311402Pemetrexed Sodium Methyl Ester
Prodotto controllato<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Formula:C21H22N5NaO6Colore e forma:NeatPeso molecolare:463.4192-AMINO-4-(3-INDOLYL)PYRIMIDINE
CAS:Purezza:97.0%Colore e forma:SolidPeso molecolare:210.24000549316406Ref: 10-F053934
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta25gPrezzo su richiesta4-(2,4-dimethoxyphenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:335.4070129394531(S)-Methyl 2-benzamido-5-guanidinopentanoate hydrochloride
CAS:Formula:C14H21ClN4O3Purezza:95.0%Peso molecolare:328.8Tenofovir Alafenamide-d5 (Diastereomers)
CAS:Prodotto controllatoFormula:C212H5H24N6O5PColore e forma:NeatPeso molecolare:481.50Febuxostat-d7
CAS:Prodotto controllato<p>Applications Febuxostat-d7, is the labeled analogue of Febuxostat-d7 (F229000), a Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formula:C16H9D7N2O3SColore e forma:NeatPeso molecolare:323.42Ondansetron Hydrochloride Dihydrate
CAS:Formula:C18H19N3O·ClH·2H2OColore e forma:Off-WhitePeso molecolare:365.85Ref: 10-F502268
1gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta3-Descyano-3-((hydroxyimino)methyl) Febuxostat
CAS:Prodotto controllatoFormula:C16H18N2O4SColore e forma:NeatPeso molecolare:334.394,6-Dihydroxypyrazolo[3,4-d]pyrimidine-13C,15N2
CAS:Prodotto controllato<p>Applications A labelled metabolite of Allopurinol.<br>References Marro, P., et al.: Brain Res., 650, 9 (1994), Abramov, A., et al.: J. Neurosci., 27, 1129 (2007), Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007),<br></p>Formula:CC4H415N2N2O2Colore e forma:White To BeigePeso molecolare:155.092-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-6-propylpyrimidin-4(3H)-one
CAS:Purezza:95.0%Peso molecolare:285.3070068359375Methotrexate Dimethyl Ester
CAS:Prodotto controllatoFormula:C22H26N8O5Colore e forma:Light YellowPeso molecolare:482.495-BENZYLOXY-2-(5-CHLORO-PYRIDIN-3-YL)-4-METHOXY-PYRIMIDINE
CAS:Purezza:95.0%Peso molecolare:327.7699890136719N-(9-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
CAS:Purezza:98%Peso molecolare:373.343994140625Methotrexate-d3 Tetraglutamate Trifluoroacetate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Methotrexate-d3 Tetraglutamate is the isotope labelled analog of Methotrexate Tetraglutamate (M260730); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C35H40D3N11O14•(C2HF3O2)xColore e forma:NeatPeso molecolare:844.82-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
CAS:Purezza:98.0%Colore e forma:SolidPeso molecolare:349.31698608398447-Methyl Memantine Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 7-Methyl Memantine is an impurity of Memantine (HCl salt, M218000) which is used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Formula:C13H23N·ClHColore e forma:White SolidPeso molecolare:229.79Ref: 10-F538203
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta4-(5-methylthiophen-2-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:273.36999511718755-(3,3-Dimethyl-ureido)-naphthalene-1-sulfonylchloride
CAS:Formula:C13H13ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:312.77Zebularine
CAS:Prodotto controllato<p>Applications It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.<br>References Driscoll, J., et al.: J. Med. Chem., 34, 3280 (1991), Ueki, T., et al.: Cancer Res., 60, 1835 (2000),Sherr, C., et al.: Cell, 116, 235 (2004), Dote, H., et al.: Clin. Cancer Res.,11, 4571 ( 2005),<br></p>Formula:C9H12N2O5Colore e forma:NeatPeso molecolare:228.204-(2,3-dimethoxyphenyl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:297.31399536132814-([1,1'-Biphenyl]-4-yl)pyrimidin-2-amine
CAS:Purezza:95+%Colore e forma:SolidPeso molecolare:247.300994873046886-Amino-1,3-dipropyl-5-nitrosouracil
CAS:Prodotto controllato<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>Formula:C10H16N4O3Colore e forma:NeatPeso molecolare:240.264-(3,4-dimethylphenyl)-6-(3-methylphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:289.3819885253906Caffeine-13C
CAS:<p>Applications Caffeine-13C is carbon-13 labeled Caffeine (C080100). Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.A study at Johns Hopkins University indicates that caffeine can improve pattern separation memory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Chem. and Eng. News p.34, Jan. 20, (2014)<br></p>Formula:C713CH10N4O2Colore e forma:NeatPeso molecolare:195.18(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:311.2980041503906Ref: 10-F036343
10gPrezzo su richiesta1kgPrezzo su richiesta25gPrezzo su richiesta100gPrezzo su richiesta500gPrezzo su richiestaTenofovir Phosphate Diammonia Salt, >90%
CAS:Prodotto controllato<p>Applications Tenofovir Phosphate Diammonia Salt is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Michelson, A.M., et al.: Biochim. Biophys. Acta, 91, 1 (1964); Rosenberg, I., et al.: Collect. Czeck. Chem. Commun., 50, 1507 (1985); Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),; Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C9H21N7O7P2Purezza:>90%Colore e forma:NeatPeso molecolare:401.25N-Demethyl Ondansetron
CAS:<p>Applications A metabolite of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bayliss, M., et al: Xenobiotica, 24, 231 (1994), Atkins, W., et al.: J. Biol. Chem., 277, 33258 (2002), De Graaf, I., et al.: Drug Metab. Dispos., 30, 1129 (2002),<br></p>Formula:C17H17N3OColore e forma:White To BrownPeso molecolare:279.341-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide
CAS:Prodotto controllatoFormula:C10H16N4O3Colore e forma:NeatPeso molecolare:240.261-tert-Butyl 3-ethyl 4-ureido-1H-pyrrole-1,3(2H,5H)-dicarboxylate
CAS:Purezza:95.0%Peso molecolare:299.3269958496094Pirimiphos-methyl, 90%
CAS:Prodotto controllato<p>Applications Pirimiphos-methyl is a phosphorothioate used as an insecticide. Pirimiphos-methyl is commonly used for mosquito control as well as control of greenhouse crop pests and stored-product insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deighton, J. et al.: Mosq. News, 34, 163 (1974); LaHue, D.W.: J. Econ. Entomol., 68, 236 (1975); Antonious, G.F. et al.: J. Entomol. Sci., 30, 191 (1995):<br></p>Formula:C11H20N3O3PSPurezza:90%Colore e forma:ColourlessPeso molecolare:305.33Uric Acid
CAS:<p>Applications Uric Acid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006);<br></p>Formula:C5H4N4O3Colore e forma:NeatPeso molecolare:168.112-(5-amino-3-methyl-1H-pyrazol-1-yl)-6-phenylpyrimidin-4(3H)-one
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:267.29199218754-(4-bromophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:354.25100708007816-Amino-2-methylpyrimidin-4-ol
CAS:Purezza:95.0%Colore e forma:LiquidPeso molecolare:125.13099670410156Tri-POC Tenofovir Dimer (>90%)
CAS:Prodotto controllato<p>Stability Very Hygroscopic<br>Applications Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil (T018505), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly.<br>References Turhanen, P. et al.: J. Org. Chem., 72, 1468 (2007);<br></p>Formula:C34H52N10O17P2Purezza:>90%Colore e forma:White To Light BeigePeso molecolare:934.78Aminopterin
CAS:<p>Impurity Methotrexate EP Impurity B<br>Applications Aminopterin (Methotrexate EP Impurity B) is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Matherly, L.H., et al.: Cancer Res., 45, 1073 (1985), Rumberger, B.G., et al.: Cancer Res., 50, 4639 (1990), Roy, K., et al.: J. Biol. Chem., 273, 2526 (1998),<br></p>Formula:C19H20N8O5Colore e forma:YellowPeso molecolare:440.411-(6-Ethoxy-2-methylsulfanyl-pyrimidin-4-yl)-piperidin-3-ylamine hydrochloride
CAS:Purezza:95.0%Peso molecolare:304.8399963378906Paraxanthine-1-methyl-d3
CAS:Prodotto controllato<p>Applications An adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formula:C72H3H5N4O2Colore e forma:YellowPeso molecolare:183.184-(4,6-Dimethoxypyrimidin-2-yl)benzoic acid
CAS:Formula:C13H12N2O4Purezza:95.0%Colore e forma:SolidPeso molecolare:260.249Sulbutiamine
CAS:Prodotto controllato<p>Applications Sulbutiamine (isobutyryl thiamine disulfide) is a lipophilic derivative of thiamine used for the treatment of asthenia and other related pathological conditions. Sulbutiamine is available over-the-counter in several countries as a component of nutritional supplements.<br>References Micheau, J., et al.: Pharmacol. Biochem. Behav., 23, 195 (1985), Bettendorff, L., et al.: Biochem. Pharmacol., 40, 2557 (1990), van Reeth, O., et al.: Drugs Today, 35, 187 (1999),<br></p>Formula:C32H46N8O6S2Colore e forma:Off WhitePeso molecolare:702.893-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
CAS:Purezza:98%Peso molecolare:649.630004882813Ref: 10-F867169
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta2-Chloro-N-piperidin-4-ylpyrimidin-4-amine hydrochloride
CAS:Purezza:97.0%Peso molecolare:249.13999938964844Xanthine-13C15N2
CAS:Prodotto controllato<p>Applications Isotope labelled analog of Xanthine (X499950), a substance that can be found in animal organs, yeast, patatoes, coffee beans, tea. Xanthine can be used to relax and widen certain breathing passages of the lungs. It is also found that a large number of derivatives that exhibits adenoside receptor antagonist properties.<br>References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011)<br></p>Formula:C413CH4N215N2O2Colore e forma:Light Yellow To Light BeigePeso molecolare:155.09N-Cyclopropyl-N'-piperidin-3-ylmethyl-pyrimidine-4,6-diamine hydrochloride
CAS:Purezza:95.0%Peso molecolare:283.799987792968754-(3,3-Dipropyl-ureido)benzenesulfonyl chloride
CAS:Formula:C13H19ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:318.82Febuxostat
CAS:<p>Applications Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formula:C16H16N2O3SColore e forma:White To Off-WhitePeso molecolare:316.37Ref: 10-F544640
1gPrezzo su richiesta5mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta2-Isopropyl-pyrimidine-5-carboxylic acid
CAS:Formula:C8H10N2O2Purezza:95.0%Colore e forma:SolidPeso molecolare:166.18Fmoc N-Hydroxysuccinimide Ester
CAS:<p>Stability Moisture Sensitive<br>Applications Used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heidenreich, O., et al.: J. Biol. Chem., 269, 2131 (1994), Kothe, U., et al.: Anal. Biochem., 356, 148 (2006), Thakkar, A., et al.: Anal. Chem., 78, 5935 (2006),<br></p>Formula:C19H15NO5Colore e forma:NeatPeso molecolare:337.33Methotrexate a-tert-Butyl Ester
CAS:Prodotto controllato<p>Applications Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Yoshii, T., et al.: J. Am. Chem. Soc., 136, 16635 (2014);<br></p>Formula:C24H30N8O5Colore e forma:NeatPeso molecolare:510.5461-(5-Bromopyrimidin-2-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS:Purezza:95.0%Peso molecolare:291.1080017089844N-(2-Hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide
CAS:Purezza:95+%Peso molecolare:469.55999755859375(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Prodotto controllato<p>Applications A acyclic phosphonate nucleotide.<br></p>Formula:C13H22N5O4PColore e forma:White SolidPeso molecolare:343.32Formaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Shock Sensitive<br>Applications Formaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic aldehyde found in mainstream cigarette smoke.<br>References Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Formula:C7H6N4O4Colore e forma:NeatPeso molecolare:210.154-(2,5-dimethoxyphenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:335.40701293945312-Chloro Adenosine
CAS:<p>Applications A selective A1-adenosine receptor agonist. Induces apoptosis.<br>References Evans, et al.: Neurosci. Lett., 83, 287 (1987), Szondy, Z.: Biochem. J., 304, 877 (1994)<br></p>Formula:C10H12ClN5O4Colore e forma:Off-WhitePeso molecolare:301.69Isoguanosine Hydrate
CAS:Prodotto controllato<p>Applications A useful synthetic intermedate. A naturally occuring, biologically active isomer of guanosine. Reported to stimulate the accumulation of cyclic-AMP in the brain. It is an inhibitor of IMP pyrophosphorylase, and its 5’-di and -tri-phosphates inhibit glutamic acid dehydrogenase. May contain approximately 0.6 moles of water.<br>References Divakar, K.J., et al.: J. Chem. Soc. Perkin Trans., 1, 771 (1991), Montsch, H.H., et al: Biochemistry, 14, 5593 (1975), Hagen, C.: Biochim. Biophys. Acta., 293, 105 (1973), Huang, M., et al.: J. Med. Chem., 15, 462 (1972)<br></p>Formula:C10H13N5O5·H2OColore e forma:NeatPeso molecolare:301.26Febuxostat 2-Butyl Isomer
CAS:Prodotto controllato<p>Applications Febuxostat 2-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C16H16N2O3SColore e forma:NeatPeso molecolare:316.374,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
CAS:Purezza:98.0%Peso molecolare:349.17001342773441-(4-tert-Butylphenyl)-2-pyrimidin-4-yl ethanol
CAS:Formula:C16H20N2OPurezza:≥95%Colore e forma:SolidPeso molecolare:256.3491-Methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine 1-oxide (Imatinib Impurity)
CAS:Purezza:98%Peso molecolare:509.6144-Amino-1,3-dimethyl-5-nitrosouracil x-H2O
CAS:Prodotto controllato<p>Applications 4-Amino-1,3-dimethyl-5-nitrosouracil is a useful building block for organic synthesis.<br></p>Formula:C6H8N4O3Colore e forma:NeatPeso molecolare:184.15Ref: 10-F603150
1gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:281.3340148925781Ondansetron
CAS:Prodotto controllato<p>Applications Ondansetron is a specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Formula:C18H19N3OColore e forma:White To Light BeigePeso molecolare:293.364,6-Dichloro-2,5-diphenylpyrimidine
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:301.1700134277344Ref: 10-F866867
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaTri-o-tolyl-Phosphine Oxide
CAS:Prodotto controllato<p>Impurity Eletriptan Impurity 14<br>Applications Tri-o-tolyl-Phosphine Oxide (Eletriptan Impurity 14) is an impurity of Eletriptan, a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines.<br>References Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998); Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999); Goadsby, P.J., et al.: Neurology, 54, 156 (2000)<br></p>Formula:C21H21OPColore e forma:NeatPeso molecolare:320.365Tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
CAS:Purezza:97%Peso molecolare:577.71002197265624-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide
CAS:Purezza:99.0%Colore e forma:SolidPeso molecolare:482.82000732421875Ref: 10-F361865
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta25gPrezzo su richiesta10mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiestaN10-Methyl Pteroic Acid
CAS:<p>Impurity Methotrexate EP Impurity D<br>Applications N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D.<br>References Cramer, S., et al.: Cancer Res. 1984, 44, 1843 (1984), Hendel, J., et al.: Eur. J. Clin. Pharmacol., 26, 103 (1984),<br></p>Formula:C15H14N6O3Colore e forma:Orange To Dark RedPeso molecolare:326.31Pentostatin
CAS:Prodotto controllato<p>Applications An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rogler-Brown, T. et al.: Biochem. Pharmacol., 28, 201 (1979); Johnston, J.B. et al.: J. Natl. Canvcer Inst., 80, 765 (1988); Fortune, A.F. et al.: Leuk. and Lymph., 51, 839 (2010); Robak, T. et al.: Drugs, 69, 2415 (2009);<br></p>Formula:C11H16N4O4Colore e forma:White To Off-WhitePeso molecolare:268.279-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one
CAS:Purezza:97%Peso molecolare:270.2200012207031Memantine-Glucose Adduct
Prodotto controllatoFormula:C18H31NO5Colore e forma:NeatPeso molecolare:341.442Ref: 10-F826449
1gPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiestaAllopurinol-13C,15N2
CAS:Prodotto controllato<p>Applications Allopurinol-13C,15N2, is the labeled analogue of Allopurinol (A547300), acting as an Xanthine oxidase inhibitor, and used in treatment of hyperuricemia and chronic gout.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978), Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005), Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005),<br></p>Formula:C413CH4N215N2OColore e forma:NeatPeso molecolare:139.09Methotrexate Dimethylamide (>90%)
CAS:Prodotto controllato<p>Applications Methotrexate Dimethylamide is an impurity of Methotrexate (M260675) which is a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C22H27N9O4Purezza:>90%Colore e forma:NeatPeso molecolare:481.508Tenofovir Alafenamide
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir Alafenamide is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C21H29N6O5PColore e forma:NeatPeso molecolare:476.47(3aS,4S,6R,6aR)-6-(6-Amino-2-chloro-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylic acid
CAS:Purezza:97.0%Peso molecolare:355.7399902343751-phenyl-5-[(pyrimidin-2-ylsulfanyl)methyl]-1H-1,2,3-triazole-4-carboxylic acid
CAS:Purezza:95.0%Peso molecolare:313.3399963378906D-Neopterin-13C5
CAS:<p>Applications Labelled precursor in the biosynthesis of Biopterin. First isolated from the pupae of bees.<br>References Kobashi, I., et al.: Agric. Biol. Chem., 35, 47 (1971), Fukushima, S., et al.: J. Biol. Chem., 247, 4549 (1972),<br></p>Formula:C413C5H11N5O4Colore e forma:Light Beige To BrownPeso molecolare:258.187-Methyl Xanthine
CAS:Prodotto controllato<p>Applications Metabolite of Theophylline and Caffeine.<br>References Yu, Ch. et al.: J. Bacteriol. 191, 4624 (2009); Geraets, L. et al.: Biochem. Pharmacol. 72, 902 (2006).<br></p>Formula:C6H6N4O2Colore e forma:NeatPeso molecolare:166.145-Acetylamino-6-amino-3-methyluracil Hydrate
CAS:Prodotto controllato<p>Applications Metabolite of Caffeine (C080100).<br>References Wong, P., et al.: J. Pharm. Biomed. Anal., 28, 693 (2002), Nyeki, A., et al.: Brit. J. Clin. Pharmacol., 55, 62 (2003), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),<br></p>Formula:C7H12N4O4Colore e forma:NeatPeso molecolare:216.196-(4-Methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS:Formula:C11H10N2O2SPurezza:95.0%Peso molecolare:234.272-(4-Chlorophenyl)amino-4-phenylpyrimidine
CAS:Purezza:95.0%Colore e forma:Solid, No data available.Peso molecolare:281.7399902343754-(furan-2-yl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:327.33999633789061,3,5-Trimethyladamantane
CAS:Prodotto controllato<p>Applications An alkyladamantane derivative that are biotransformed via strains of Pseudomonas. It is used to study alkyladamantane adsorption on graphitized thermal carbon black.<br>References Yashkin, S.N. et al.: Rus. Che,. Bull., 57, 2472 (2008); Slepen’kin, A. et al.: Nefeckhim., 33, 406 (1993);<br></p>Formula:C13H22Colore e forma:NeatPeso molecolare:178.315-Methyl-3-methylene-2-hexanone
CAS:Prodotto controllato<p>Applications 5-Methyl-3-methylene-2-hexanone is an impurity of Tetrabenazine (T284000), an antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brossi, A., et al.: Helv. Chim. Acta, 43, 583 (1960);<br></p>Formula:C8H14OColore e forma:NeatPeso molecolare:126.204-(3,4-dimethylphenyl)-6-(2-fluorophenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:293.34500122070314-(3-Chlorothiophen-2-yl)-6-methylpyrimidin-2-amine
CAS:Purezza:95+%Peso molecolare:225.69000244140625Fenclorim
CAS:Prodotto controllato<p>Applications Herbicide safener.<br>References Lee, H., et al.: Eur. J. Med. Chem., 40, 862 (2005), Wright, S., et al.: Bioorg. Med. Chem. Lett., 17, 5638 (2007), Brazier-Hicks, M., et al.: J. Biol. Chem., 283, 21102 (2008), Vinggaard, A., et al.: Chem. Res. Toxicol., 21, 813 (2008),<br></p>Formula:C10H6Cl2N2Colore e forma:BeigePeso molecolare:225.074-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester
CAS:Prodotto controllato<p>Applications 4-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the synthesis of furoxanoxyalkyl esters of pemetrexed as antifolates and nitric oxide donors for use as anticancer agents and their activities against four human cancer cell lines.<br>References Min, T., et al.: Med. Chem. Res., 18, 495 (2009); Barnett, C.J., et al.: Org. Process Res. Dev., 3, 184 (1999)<br></p>Formula:C12H13BrO3Colore e forma:NeatPeso molecolare:285.13Ref: 10-F047247
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta2,5-Ethyl Acetate Febuxostat
CAS:Prodotto controllato<p>Applications Febuxostat (F229000) is the parent compound for 2,5-Ethyl Acetate Febuxostat. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formula:C20H25NO5SColore e forma:NeatPeso molecolare:391.48N-(3,4-Dimethoxyphenethyl)formamide
CAS:Prodotto controllato<p>Applications N-(3,4-Dimethoxyphenethyl)formamide is an impurity of Tetrabenazine (T284000), an antipsychotic.<br>References Schwartz, D., et al.: Biochem. Pharmacol., 15, 645 (1966),<br></p>Formula:C11H15NO3Colore e forma:NeatPeso molecolare:209.242N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyladenosine
CAS:Purezza:95%Peso molecolare:687.7535-CHLORO-N2-(4-FLUOROBENZYL)-N4-(5-ISOPROPOXY-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE
CAS:Purezza:95.0%Peso molecolare:376.820007324218754-(Tert-butyl)-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)benzamide
CAS:Purezza:98%Peso molecolare:438.54998779296875
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