Steroidi e Derivati
Gli steroidi sono composti organici con una struttura a quattro anelli fusi, nota come nucleo steroideo. Questo nucleo può essere legato a vari gruppi funzionali che ne modificano le proprietà e le funzioni biologiche. Gli steroidi svolgono un ruolo chiave nella regolazione dei processi metabolici e ormonali. Sono utilizzati in medicina per il trattamento di disturbi infiammatori, malattie autoimmuni e squilibri ormonali. Inoltre, alcuni derivati degli steroidi possiedono potenti proprietà antinfiammatorie, come i corticosteroidi. In terapie specifiche, vengono impiegati per ridurre l’infiammazione e controllare il dolore in diverse patologie.
Presso CymitQuimica, offriamo una varietà di steroidi e loro derivati per la ricerca e lo sviluppo farmaceutico.
Trovati 4974 prodotti di "Steroidi e Derivati"
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6,7-Dihydrocanrenone
CAS:Prodotto controllatoFormula:C22H30O3Colore e forma:NeatPeso molecolare:342.47rac 7-Methoxy Lasofoxifene
CAS:Prodotto controllato<p>Applications Lasofoxifene intermediate.<br>References Rosati, R., et al.: J. Med. Chem., 41, 2928 (1998),<br></p>Formula:C29H33NO2Colore e forma:NeatPeso molecolare:427.58Exemestane-13C,D3
CAS:Prodotto controllato<p>Applications Exemestane-13C,D3 is the labeled analogue of Exemestane (E957000), an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Formula:C1913CH21D3O2Colore e forma:NeatPeso molecolare:300.41Vitamin D3 b-D-Glucuronide, >90%
CAS:Prodotto controllato<p>Stability Temperature and Light Sensitive<br>Applications A metabolite of Vitamin D3.<br>References Bell, P.A., et al.: Biochem. J., et al.: 115, 663 (1969), Kumar, R.S., et al.: J. Clin. Invest., 65, 277 (1980), Shimada, K., et al.: Biol. Pharm. Bull., 19, 491 (1996),<br></p>Formula:C33H52O7Purezza:>90%Colore e forma:NeatPeso molecolare:560.7621-Carboxy Dexamethasone
CAS:<p>Applications 21-Carboxy Dexamethasone is a useful research chemical.<br>References Shepard, Allan R., ACS Chem. Biol., 3, 549-558(2013);<br></p>Formula:C22H27FO6Colore e forma:White To Off-WhitePeso molecolare:406.44(16α)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS:Prodotto controllatoFormula:C24H30O6Colore e forma:NeatPeso molecolare:414.49Dexamethasone acetate monohydrate
CAS:Dexamethasone acetate treats rheumatic issues, skin conditions, asthma, allergies, COPD, brain swelling, croup, TB adjunct.Formula:C24H33FO7Colore e forma:SolidPeso molecolare:452.523-(N-Phenyl-N-methyl)aminoacrolein
CAS:<p>3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.</p>Formula:C10H11NOPurezza:Min. 97 Area-%Colore e forma:PowderPeso molecolare:161.2 g/mol(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
CAS:Formula:C24H40O4Purezza:98%Colore e forma:SolidPeso molecolare:392.58Boldione (1 mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C19H24O2Colore e forma:Single SolutionPeso molecolare:284.392-Hydroxy Atorvastatin Lactone
CAS:Prodotto controllato<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Formula:C33H33FN2O5Colore e forma:Off White SolidPeso molecolare:556.622-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Prodotto controllato<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formula:C23H25N5O3Purezza:90%Colore e forma:NeatPeso molecolare:419.48Deflazacort-d3 (Major)
CAS:Prodotto controllatoFormula:C25H28D3NO6Colore e forma:NeatPeso molecolare:444.54Cortisol-D4 21-Sulfate Potassium Salt
CAS:Prodotto controllato<p>Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Formula:C21H25D4KO8SColore e forma:NeatPeso molecolare:484.64Testosterone (1 mg/mL in Acetonitrile)
CAS:Prodotto controllatoFormula:C19H28O2Colore e forma:ColourlessPeso molecolare:288.42Testosterone-16,16,17-d3 17-Decanoate
CAS:Prodotto controllato<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Formula:C292H3H43O3Colore e forma:NeatPeso molecolare:445.69Digitoxigenin Mono-β-D-digitoxoside
CAS:Prodotto controllatoFormula:C29H44O7Colore e forma:White To Off-WhitePeso molecolare:504.666β,17α-Dihydroxyprogesterone
CAS:Prodotto controllatoFormula:C21H30O4Colore e forma:NeatPeso molecolare:346.4613-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS:Prodotto controllato<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Formula:C21H30OColore e forma:NeatPeso molecolare:298.464-Hydroxy Estradiol 1-N3-Adenine
CAS:Prodotto controllato<p>Applications 4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formula:C23H27N5O3Colore e forma:NeatPeso molecolare:421.499-Chloro Triamcinolone Acetonide 21-Acetate
CAS:Prodotto controllato<p>Applications Triamcinolone Acetonide (T767165) impurity.<br></p>Formula:C26H33ClO7Colore e forma:WhitePeso molecolare:492.98917α,21-Dideoxy-6α,9α-Difluoroprednisolone
CAS:Prodotto controllato<p>Applications 17α,21-Dideoxy-6α,9α-Difluoroprednisolone is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)<br></p>Formula:C20H24F2O4Colore e forma:NeatPeso molecolare:366.46-Deschloro Cyproterone Acetate
CAS:Prodotto controllato<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Formula:C24H30O4Colore e forma:NeatPeso molecolare:382.4932-Methyl Ethynyl Estradiol
CAS:Prodotto controllato<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Formula:C21H26O2Colore e forma:NeatPeso molecolare:310.43Betamethasone 21-Mesylate (>90%)
CAS:Prodotto controllatoFormula:C23H31FO7SPurezza:>90%Colore e forma:NeatPeso molecolare:470.55Estratetraenol
CAS:Prodotto controllato<p>Applications A steroid produced by females having pheromone activities.<br>References Kotiyan, P., et al.: J. Pharm. Biomed. Anal., 22, 667 (2000), Bensafi, M., et al.: Behaviour. Brain Res., 152, 11 (2004), Zhu, B., et al.: Endocrinol., 147, 4132 (2006), Bellavance, E., et al.: J. Med. Chem., 52, 7488 (2009),<br></p>Formula:C18H22OColore e forma:NeatPeso molecolare:254.374-Methylestrone
CAS:Prodotto controllato<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Formula:C19H24O2Colore e forma:NeatPeso molecolare:284.39Testosterone Oleate
CAS:Prodotto controllatoFormula:C37H60O3Colore e forma:NeatPeso molecolare:552.871,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS:<p>Stability Hygroscopic<br>Applications A degradation product of Betamethasone (B327000).<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Formula:C28H39FO7Colore e forma:NeatPeso molecolare:506.60Dutasteride-13C6
CAS:Prodotto controllato<p>Applications Labelled Dutasteride (D735000). Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C2113C6H30F6N2O2Colore e forma:NeatPeso molecolare:534.49Latanoprost Tris(triethylsilyl) Ether
CAS:Prodotto controllato<p>Impurity Latanoprost USP Related Compound D<br>Applications Latanoprost derivative. Latanoprost related compound D. Latanoprost USP Related Compound D.<br></p>Formula:C44H82O5Si3Colore e forma:ColourlessPeso molecolare:775.38(4S,trans)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Prodotto controllatoFormula:C14H27NO4Colore e forma:NeatPeso molecolare:273.376α-Chloro-17-acetoxy Progesterone
CAS:<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Formula:C23H31ClO4Colore e forma:NeatPeso molecolare:406.943Betamethasone 21-Acetate-d3
CAS:Prodotto controllato<p>Applications Betamethasone 21-Acetate-d3, is the labeled analogue of Betamethasone 21-Acetate (B327025), which is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formula:C24H28D3FO6Colore e forma:NeatPeso molecolare:437.52Desogestrel
CAS:Prodotto controllato<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formula:C22H30OColore e forma:White To Off-WhitePeso molecolare:310.476α-Hydroxy-21-desacetyl Deflazacort
CAS:Prodotto controllato<p>Applications The minor metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formula:C23H29NO6Colore e forma:NeatPeso molecolare:415.48Ciclesonide-d7
CAS:Prodotto controllato<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formula:C32H37D7O7Colore e forma:NeatPeso molecolare:547.739α-Bromobudesonide
CAS:Prodotto controllato<p>Impurity Budesonide EP Impurity J<br>Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Formula:C25H33BrO6Colore e forma:NeatPeso molecolare:509.43N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Prodotto controllato<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formula:C25H38N2O2Colore e forma:NeatPeso molecolare:398.5817α-Methyl-4-[(phenylthio)methyl]testosterone
CAS:Prodotto controllato<p>Applications Testosterone (T155000) derivative.<br></p>Formula:C27H36O2SColore e forma:NeatPeso molecolare:424.64Prednicarbate
CAS:Prodotto controllato<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Formula:C27H36O8Colore e forma:Off-WhitePeso molecolare:488.57(E/Z)-17-Deacetylnorgestimate
CAS:Prodotto controllatoFormula:C21H29NO2Colore e forma:NeatPeso molecolare:327.46Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Formula:C22H32FO11PS•xNaColore e forma:NeatPeso molecolare:554.52229810b-Hydroxy D-(-)-Norgestrel
CAS:<p>Applications 10β-Hydroxy D-(-)-Norgestrel is an impurity of Levonorgestrel (N689510).<br>References Gorog, S. et al.: J. Pharmac. Biomed. Anal., 14, 85 (1995); Berta, R. et al.: J. Pharmac. Biomed. Anal., 54, 458 (2011); Choudhary, M. I. et al.: Nat. Prod. Res., 20, 1074 (2006);<br></p>Formula:C21H28O3Colore e forma:White To Off-WhitePeso molecolare:328.445(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (Bimatoprost Impurity)
CAS:Prodotto controllatoFormula:C18H24O4Colore e forma:NeatPeso molecolare:304.38Cholesterol 5α,6α-Epoxide
CAS:Prodotto controllato<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Formula:C27H46O2Colore e forma:NeatPeso molecolare:402.6520-Hydroxydexamethasone
CAS:Prodotto controllatoFormula:C22H31FO5Colore e forma:NeatPeso molecolare:394.48Estriol 3,16a,17b-Triacetate
CAS:Prodotto controllato<p>Applications Estriol 3,16α,17β-Triacetate is a triacetate derivative of Estriol (E888960) with contraceptive activity.<br>References Wotiz, H.H., et al.: J. Reprod. Fertil., 26, 363 (1971)<br></p>Formula:C24H30O6Colore e forma:NeatPeso molecolare:414.49
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