Peptidi e Proteine
I peptidi sono corte catene di amminoacidi legate da legami peptidici, mentre le proteine sono catene di amminoacidi più lunghe e complesse, capaci di assumere strutture tridimensionali funzionali. Entrambi i tipi di composti sono essenziali per diverse funzioni biologiche, come la catalisi delle reazioni (enzimi), la difesa immunitaria (anticorpi) e la segnalazione cellulare. Le proteine hanno una struttura gerarchica che comprende la sequenza di amminoacidi e le strutture secondaria, terziaria e quaternaria. I peptidi vengono utilizzati in terapie farmaceutiche e cosmetiche per le loro specifiche proprietà biologiche, ad esempio nel trattamento di malattie metaboliche o nel miglioramento della rigenerazione cellulare. Le proteine, invece, trovano applicazioni in biotecnologia, nutrizione e medicina rigenerativa.
Presso CymitQuimica, offriamo peptidi e proteine di alta purezza per la ricerca in biotecnologia e applicazioni terapeutiche.
Trovati 3121 prodotti di " Peptidi e Proteine"
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(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid
CAS:Prodotto controllatoFormula:C9H16N2O3Colore e forma:NeatPeso molecolare:200.233,3’,5-Triiodo-D-thyronine
CAS:Prodotto controllato<p>Applications 3,3’,5-Triiodo-D-thyronine is a structural analogue o the thyroid homonef Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum.<br>References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)<br></p>Formula:C15H12I3NO4Colore e forma:Off-White To Light BrownPeso molecolare:650.97L-Threonine
CAS:Prodotto controllato<p>Applications L-enantiomer of Threonine. An essential amino acid for human development; last of the common amino acids to be discovered. Identified in oat protein.<br>References LeMaster, D.M., et al.: J. Biol. Chem., 257, 1224 (1982), Ballevre, O., et al.: Anal. Biochem., 193, 212 (1991), Roufs, J.B., et al.: Med. Hypotheses, 34, 20 (1991), Blin, O., et al.: J. Neurol., 239, 79 (1992),<br></p>Formula:C4H9NO3Colore e forma:NeatPeso molecolare:119.12Sacubitril Sodium Salt
CAS:Formula:C24H28NO5·NaColore e forma:White To Off-WhitePeso molecolare:433.473Glecaprevir
CAS:Prodotto controllato<p>Applications Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.<br>References Kwo, P., et. al.: J. Hepatol, 67, 263 (2017)Gane, E., et. al.: N. Engl. J. Med, 377, 1448 (2017)<br></p>Formula:C38H46F4N6O9SColore e forma:NeatPeso molecolare:838.86Dl-valine
CAS:Prodotto controllato<p>Applications Dl-valine<br></p>Formula:C5H11NO2Colore e forma:NeatPeso molecolare:117.15N-2-(Hydroxyethyl)-L-valine-d4 (Technical grade)
CAS:Prodotto controllato<p>Applications Labelled N-2-(Hydroxyethyl)-L-valine (H942300). Cotinine and N-(2-hydroxyethyl)valine are markers of passive exposure to tobacco smoke in children.<br>References Dempsey, D., et al.: Clin. Pharmacol. Ther., 67, 458 (2000), Smith, C., et al.: Food Chem. Toxicol., 41, 807 (20030,<br></p>Formula:C7H11D4NO3Colore e forma:WhitePeso molecolare:165.22Daptomycin
CAS:<p>Applications Daptomycin is a Cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.<br>References Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987), Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1999),<br></p>Formula:C72H101N17O26Colore e forma:Light YellowPeso molecolare:1620.67Vasopressin Acetic Acid Salt
CAS:Prodotto controllato<p>Applications Vasopressin Acetic Acid Salt is an acidic salt of Vasopressin (V991530), an antidiurectic hormone.<br>References Tokushige, S., et al.: Internal Medicine, 55, 1199 (2016)<br></p>Formula:C46H65N15O12S2•(C2H4O2)Colore e forma:NeatPeso molecolare:1084.236005Carbetocin
CAS:<p>Applications An obstetric drug used to control postpartum hemorrhaging.<br>References Sanz-Nebot, V., et al.: Anal. Bioanal. Chem., 377, 306 (2003), Gimpl, G., et al.: Eur. J. Pharmacol., 510, 9 (2005), Handler, J., et al.: Theriogenol., 66, 1397 (2006), Klenerova, V., et al.: J. Physiol. Pharmacol., 60, 57 (2009),<br></p>Formula:C45H69N11O12SColore e forma:NeatPeso molecolare:988.16trans-4-Hydroxy-L-proline
CAS:Prodotto controllato<p>Applications A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.<br>References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);<br></p>Formula:C5H9NO3Colore e forma:NeatPeso molecolare:131.13N-des-succinyl-Sacubitril hydrochloride
CAS:Prodotto controllato<p>Applications (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.<br>References Liu, M., et al.: Faming Zhuanli Shenqing. CN 105168205 A 20151223. Dec 23, 2015; Wang, Z.: PCT Int. Appl. WO 2015154673 A1 20151015. Oct 15, 2015<br></p>Formula:C20H25NO2·HClColore e forma:NeatPeso molecolare:384.34(S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid
CAS:Prodotto controllato<p>Applications (S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid is an intermediate for Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C31H42N4O6Colore e forma:NeatPeso molecolare:566.69(R)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium Chloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications (R)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride is an important co-factor of mammalian mitochondrial energy metabolism. It is also a good active ingredient for dry-skin.<br>References Geier, David A., et al.: Neurochem. Res., 38(11), 2336-2341 (2013);Tanno, Osamu, et al.: Fragrance J., 33(8), 82-85 (2005);<br></p>Formula:C7H16NO3·ClColore e forma:White To Off-WhitePeso molecolare:197.660N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
CAS:<p>Impurity Bortezomib USP Impurity B<br>Applications N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.<br>References Pekol, T., et al.: Drug. Meta. Disp., 33, 771 (2005); Hsieh, F.Y., et al.: J. Pharma. Biomed. Anal., 49, 115 (2009);<br></p>Formula:C14H14N4O2Colore e forma:NeatPeso molecolare:270.29(±)-Methionine
CAS:<p>Applications (±)-Methionine is an essential amino acid involved in various biochemical processes in humans and mammals. Also in poultry meal as a source of nutrition.<br>References Martin-Venegas, R. et al.: Food Chem., 141, 1702 (2013); Austic, R. et al.: J. Agri. Food Chem., 61, 7341 (2013); Yan, L. et al.: J. Anim. Phys Anim Nutr., 97, 457 (2013);<br></p>Formula:C5H11NO2SColore e forma:WhitePeso molecolare:149.213,3',5,5'-Tetraiodo Thyroformic Acid (>90%)
CAS:<p>Impurity Levothyroxine EP Impurity H; T4-Benzoic Acid (USP)<br>Applications 3,3',5,5'-Tetraiodo Thyroformic Acid (Levothyroxine EP Impurity H; T4-Benzoic Acid (USP)) is a thyroid hormone analogue and a potent Thyroxine impurity.<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>Formula:C13H6I4O4Purezza:>90%Colore e forma:White To Light BrownPeso molecolare:733.80Tabimorelin
CAS:Prodotto controllato<p>Applications NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4.<br>References Fabre, G., et al.: Biochem. Pharmacol., 37, 4389 (1988), Thummel, K., et al.: Clin. Pharmacol. Ther., 59, 491 (1996), Yu, D., et al.: J. Clin. Pharmacol., 39, 1203 (1999),<br></p>Formula:C32H40N4O3Colore e forma:NeatPeso molecolare:528.68N,N-Dimethyl-4-hydroxymethoxy Clomiphene (~90%, contains ~10% Z-isomer)
CAS:Prodotto controllatoFormula:C25H26ClNO3Colore e forma:NeatPeso molecolare:423.93N-Nitroso Lisinopril
CAS:Formula:C21H30N4O6Colore e forma:White To Light YellowPeso molecolare:434.486Eptifibatide
CAS:Prodotto controllato<p>Applications An arginine-glycine-aspartate-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.<br>References Pathak, A., et al.: Cardiovas. Diabetol., 7 (2008), Hantgan, R., et al.: Biochem., 48, 8355 (2009), Giugliano, R., et al.: New Eng. J. Med., 360, 2176 (2009),<br></p>Formula:C35H49N11O9S2Colore e forma:Off White SolidPeso molecolare:831.96Carfilzomib (2R,4R)-Diol
Prodotto controllato<p>Applications Carfilzomib (2R,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H59N5O8Colore e forma:NeatPeso molecolare:737.93Perfluorophenol
CAS:Prodotto controllato<p>Applications Perfluorophenol is used in the synthesis of PGA-films as biodegradable polymers. It also participates in the synthesis of tripod macrocyclic Gd(III) chelates for cancer molecular MRI.<br>References Lee, K. et al.: Langmuir., 20, 2531 (2004); Zhou, Z. et al.: Biomater., 34, 7683 (2013);<br></p>Formula:C6HF5OColore e forma:NeatPeso molecolare:184.06(R)-Hydroxy Des(boric Acid) Bortezomib
CAS:Prodotto controllato<p>Impurity Bortezomib USP Impurity I<br>Applications (R)-Hydroxy Des(boric acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C. et al.: Chem. and Eng. News, 87, 41 (2009)<br></p>Formula:C19H24N4O3Colore e forma:NeatPeso molecolare:356.42Bortezomib
CAS:Prodotto controllato<p>Stability Hygroscopic and Moisture Sensitive<br>Applications Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);<br></p>Formula:C19H25BN4O4Colore e forma:White To Off-WhitePeso molecolare:384.24Carfilzomib
CAS:Prodotto controllato<p>Applications Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H57N5O7Colore e forma:White To Off-WhitePeso molecolare:719.91Voclosporin-d4
CAS:Prodotto controllato<p>Applications Labelled Voclosporin (V678500). A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant.<br>References Aspeslet, L., et al.: Transplant Proc., 33, 1048 (2001), Cho, M., et al.: Arthritis Rheum., 46, 1202 (2002), Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2004),<br></p>Formula:C63H107D4N11O12Colore e forma:NeatPeso molecolare:1218.65Oxytocin-d5 Trifluoroacetate
CAS:Prodotto controllato<p>Applications Labelled Oxytocin. The principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.<br>References Pierce, et al.: J. Biol. Chem., 199, 929 (1952), Tuppy, et al.: Biochem. Biophys. Acta, 11, 449 (1953), Cash, et al.: J. Med. Pharm. Chem., 5, 413 (1962), Nachtmann, F., et al.: Anal. Profiles Drug Subs., 10, 563 (1981),<br></p>Formula:C45H62D5F3N12O14S2Colore e forma:White To Off-WhitePeso molecolare:1126.24Desethyl Sacubitril-d4
CAS:Prodotto controllatoFormula:C22H21D4NO5Colore e forma:NeatPeso molecolare:387.46Teduglutide-d8 TFA salt x hydrate (Leu-methyl-d3+Phe-d5)
CAS:Prodotto controllato<p>Applications Teduglutide-d8 TFA salt x hydrate (Leu-methyl-d3+Phe-d5) is an isotopically labelled form of Teduglutide (T013795), which is glucagon-like peptide-2 (GLP-2) analogue that is used for the treatment of short bowel syndrome.<br>References Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br>Chemical Name: Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br></p>Formula:C164H244D8N44O55S•C2HF3O2•x(H2O)Colore e forma:NeatPeso molecolare:3760.081140218Cyclosporin C
CAS:Prodotto controllato<p>Applications A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Formula:C62H111N11O13Purezza:>80%Colore e forma:NeatPeso molecolare:1218.61Bortezomib-D8 (Major)
CAS:Prodotto controllato<p>Applications Labelled Bortezomib, which the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells.d6-3%d7-10%d8-86%<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005)<br></p>Formula:C19H17D8BN4O4Colore e forma:Off-WhitePeso molecolare:392.29L-Methionine
CAS:<p>Applications Essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier.<br>References Benevenga, N.J., et al.: J. Agric. Food Chem., 22, 2 (1974), Fleisher, L.D., et al.: Clin. Endocrinol. Metab., 3, 37 (1974), Meinnel, T., et al.: Biochimie, 75, 1061 (1993),<br></p>Formula:C5H11NO2SColore e forma:White To Off-WhitePeso molecolare:149.215-9-Leuprolide xTFA Salt
CAS:Prodotto controllato<p>Applications 5-9-Leuprolide is a metabolite of Leuprolide (L330590), a gonadotropin-releasing hormone (GnRH) analogue acting as an agonist at pituitary GnRH receptors.<br>References Handelsman, David J., et al.: J. of Steroid Biochem. and Mol. Bio., 141, 113-120 (2014);Okada, Hiroaki, et al.: Pharma. Res., 8(6), 787-91 (1991)<br></p>Formula:C34H57N9O6·x(C2HF3O2)Colore e forma:NeatPeso molecolare:687.87+ x(114.02)Protoporphyrin-9
CAS:<p>Stability Light Sensitive<br>Applications Protoporphyrin-9 is the precursor to heme sites and chlorophyll.<br></p>Formula:C34H34N4O4Colore e forma:NeatPeso molecolare:562.66Teduglutide
CAS:<p>Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).</p>Formula:C164H252N44O55SPurezza:98.08%Colore e forma:SolidPeso molecolare:3752.08L-Valine-d8
CAS:Prodotto controllato<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Formula:C52H8H3NO2Colore e forma:NeatPeso molecolare:125.203-Mercaptopropionic Acid
CAS:Prodotto controllato<p>Applications 3-Mercaptopropionic Acid (cas# 107-96-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C3H6O2SColore e forma:NeatPeso molecolare:106.14γ-Cyclodextrin
CAS:<p>Stability Hygroscopic<br>Applications γ-Cyclodextrin is used as nanomolecular encapsulation for drug delivery and pharmaceuticals. Used in the synthesis of unilamellar vesicles.<br>References Ikeda, A. et al.: Chem. Comm., 50, 1288 (2014); Gudmundsdottir, B. et al.: J. Ocular Pharm. Ther., 30, 35 (2014);<br></p>Formula:C48H80O40Colore e forma:WhitePeso molecolare:1297.12Pidotimod
CAS:Prodotto controllato<p>Applications Immunostimulant used in patients with cell-mediated immunodepression.<br>References Gu, C., et al.: Pharm. Res., 25, 979 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Giagulli, C., et al.: Int. Immunopharmacol., 9, 1366 (2009),<br></p>Formula:C9H12N2O4SColore e forma:NeatPeso molecolare:244.27Thyroxine 4’-O-β-D-Glucuronide
CAS:<p>Applications Thyroxine 4-O-β-D-Glucuronide is a major metabolite and glucuronide conjugate of Thyroxine (T425600) formed via the glucuronidation of the phenyl hydroxyl group.<br>References Tong, Z. et al.: Drug Metab. Dispos., 35, 2203 (2007); West, C.D. et al.: J. Clin. INvest., 42, 1134 (1963);<br></p>Formula:C21H19I4NO10Colore e forma:NeatPeso molecolare:952.99(2R,4R)-Sacubitril
CAS:<p>Applications (2R,4R)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Formula:C24H29NO5Colore e forma:NeatPeso molecolare:411.491L-Prolinamide
CAS:<p>Applications Proline based organocatalyst.<br>References Alberg, D., et al.: Bioorg. Med. Chem. Lett., 19, 3888 (2009), Huang, X., et al.: J. Phys. Chem., 114, 1068 (2010),<br></p>Formula:C5H10N2OColore e forma:White SolidPeso molecolare:114.1463,5,3',5'-Tetraiodo Thyromandelic Acid (>85%)
CAS:Prodotto controllato<p>Impurity Levothyroxine T4-Hydroxyacetic Acid; T4-Hydroacetic Acid (USP)<br>Stability Hygroscopic<br>Applications 3,5,3',5'-Tetraiodo Thyromandelic Acid (Levothyroxine T4-Hydroxyacetic Acid; T4-Hydroacetic Acid (USP)) is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>Formula:C14H8I4O5Purezza:>85%Colore e forma:Light Orange Colour To BrownPeso molecolare:763.834-Methylbenzenesulfonic Acid Monohydrate
CAS:Prodotto controllato<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>Formula:C7H8O3S·H2OColore e forma:WhitePeso molecolare:190.22GSK1904529A
CAS:<p>GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .</p>Formula:C44H47F2N9O5SPurezza:98.2% - 99.38%Colore e forma:SolidPeso molecolare:851.96(S)-Lisinopril-d5 Sodium
CAS:Prodotto controllatoFormula:C21H26D5N3NaO5Colore e forma:NeatPeso molecolare:433.51(4R)-1-Methyl-4-propyl-L-proline Hydrochloride
CAS:Prodotto controllato<p>Applications Proline derivative, and an intermediate in the production of biosynthetic antibiotics.<br></p>Formula:C9H17NO2·ClHColore e forma:NeatPeso molecolare:207.70MK 677
CAS:<p>Applications MK-677 is a potent, non-peptide ghrelin receptor agonist.<br>References Kirstie, A., et al.: Mol. Pharmacol., 76, 802 (2009); Birgitte, H. et al.: Mol. Pharmacol., 75, 44 (2009)<br></p>Formula:C27H36N4O5S·CH4SO3Colore e forma:NeatPeso molecolare:624.80Lopinavir Metabolite M-1
CAS:Prodotto controllato<p>Applications A major metabolite of Lopinavir (L469480) . It is a COVID19-related research product.<br>References Molla, A., et al.: J. Virology, 250, 255 (1998), Sham, H., et al.: Antimicrob. Agents Chemother., 42, 3218 (1998), Kumar, G., et al.: Drug Metab. Dispos., 27, 86 (1999),<br></p>Formula:C37H46N4O6Colore e forma:NeatPeso molecolare:642.785-Oxo-DL-proline-d5
CAS:Prodotto controllato<p>Applications 5-Oxo-DL-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>Formula:C52H5H2NO3Colore e forma:NeatPeso molecolare:134.14Tert-butyl Acetate
CAS:Prodotto controllato<p>Applications Tert-butyl Acetate is a common solvent used in the production of various industrial cleansers, thinners and adhesives and is also known as a VOC.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackay, D., et al.: SAR. QSAR. Enviro. Res., 23, 205 (2012); Yang, Y.S., et al.: Toxicol. Res., 26, 293 (2010);<br></p>Formula:C6H12O2Colore e forma:ColourlessPeso molecolare:116.163,5,3',5'-Tetraiodo Thyroaldehyde
CAS:Prodotto controllato<p>Impurity Levothyroxine EP Impurity I; T4-Aldehyde (USP)<br>Applications 3,5,3',5'-Tetraiodo Thyroaldehyde (Levothyroxine EP Impurity I; T4-Aldehyde (USP)) is a Thyroid hormone analogue and a Thyroxine (T425600) analogue.<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>Formula:C13H6I4O3Colore e forma:Light Beige To BrownPeso molecolare:717.80Lopinavir
CAS:<p>Stability Hygroscopic<br>Applications A selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Formula:C37H48N4O5Colore e forma:White SolidPeso molecolare:628.8013C6-Lys Octreotide Trifluoroacetate
CAS:Prodotto controllatoFormula:C4313C6H66N10O10S2•xC2HF3O2Colore e forma:White To Off-WhitePeso molecolare:1025.2011402Lopinavir-d8
CAS:Prodotto controllato<p>Applications A labelled selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Formula:C37D8H40N4O5Colore e forma:Light YellowPeso molecolare:636.85Liraglutide
CAS:Prodotto controllatoFormula:C172H265N43O51Colore e forma:Off-WhitePeso molecolare:3751.24-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid Methyl Ester
CAS:Prodotto controllato<p>Applications Remifentanil derivative.<br>References James, M.K., et al.: J. Pharmacol. Exp. Ther., 259, 712 (1991), Hoffman, W.E., et al.: Anesthesiology, 79, 107 (1993), Selinger, K., et al.: J. Pharm. Biomed. Anal., 12, 243 (1994), Richardson, T.D., et al.: Expert Opin. Drug Saf., 4, 643 (2005),<br></p>Formula:C20H24N2O2Colore e forma:NeatPeso molecolare:324.4168Bivalirudin Plus-Gly Fragment Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Formula:C100H141N25O34•xC2HF3O2Colore e forma:NeatPeso molecolare:2237.34 + x(114.02)Thyroxine Sodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.<br>References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),<br></p>Formula:C15H10I4NO4·NaColore e forma:NeatPeso molecolare:798.85Semaglutide Impurity 56 (D-Glu 21)
<p>D-Glu(21)-Semaglutide is a semaglutide impurity. The amino acid at position 21 has been replaced by the D-form of the amino acid D-glutamic acid (D-Glu). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molD-Phe(6)-Semaglutide
<p>D-Phe(6)-Semaglutide is a semaglutide impurity. The amino acid at position 6 has been replaced by the D-form of the amino acid D-phenylalanine (D-Phe). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/mol3,3',5,5'-Tetraiodothyroformic acid
CAS:<p>Cymit Quimicaetic beta-D-glucosiduronic acid</p>Formula:C13H6I4O4Purezza:Min. 95 Area-%Colore e forma:Off-White PowderPeso molecolare:733.8 g/molD-His(1)-Semaglutide
<p>D-His(1)-Semaglutide is a semaglutide impurity. The amino acid at position 1 has been replaced by the D-form of the amino acid D-histidine (D-His). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molD-Ser(8)-Semaglutide
<p>D-Ser(8)-Semaglutide is a semaglutide impurity. The amino acid at position 8 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molD-Thr(5)-Semaglutide
<p>D-Thr(5)-Semaglutide is a semaglutide impurity. The amino acid at position 5 has been replaced by the D-form of the amino acid D-threonine (D-Thr). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/mol(S,E)-N-(1-(3-Methylbut-1-enylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
CAS:<p>R-N-(1-(3-methylbut-1-enyl)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide is a drug product that is used for the treatment of bacterial infections. The compound is an impurity in the synthesis of other compounds and is also used as an analytical standard. It is synthesized from commercially available starting materials and through custom synthesis. R-N-(1-(3-methylbut-1-enyl)-1--oxo--3--phenylpropan--2--yl)pyrazine--2--carboxamide has been shown to be metabolized by CYP450 enzymes, which are responsible for the metabolism of many drugs. R-(1-(3Methylbut 1Enylamino)-1Oxo 3Phenylpropan 2Yl)Pyrazine 2Carboxamide has not been evaluated as a drug product and therefore does not</p>Formula:C19H22N4O2Purezza:Min. 95%Peso molecolare:338.4 g/molD-Val(10)-Semaglutide
<p>D-Val(10)-Semaglutide is a semaglutide impurity. The amino acid at position 10 has been replaced by the D-form of the amino acid D-valine (D-Val). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molSemaglutide Impurity 60 (D-Arg 30)
<p>D-Arg(30)-Semaglutide is a semaglutide impurity. The amino acid at position 30 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molDes-His(1)-Semaglutide
<p>Des-His(1)-semaglutide is a semaglutide-related impurity. This des-amino acid form has the histidine (His) amino acid from position 1 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.</p>Formula:C181H284N42O58Peso molecolare:3,976.5 g/molLinear Semaglutide
<p>Linear semaglutide, or simply L-Sema, is the semaglutide compound without the lipid side chain modification. It is essentially a linear version of the peptide.</p>Formula:C152H230N42O47Peso molecolare:3,397.76 g/molD-Ser(11)-Semaglutide
<p>D-Ser(11)-Semaglutide is a semaglutide impurity. The amino acid at position 11 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molD-Ala-(19)-Semaglutide
<p>D-Ala(19)-Semaglutide is a semaglutide impurity. The amino acid at position 19 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molSemaglutide Impurity 101 (D-Glu 3)
<p>D-Glu(3)-Semaglutide is a semaglutide impurity. The amino acid at position 3 has been replaced by the D-form of the amino acid D-glutamic acid (D-Glu). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molDes-Glu(3)-Semaglutide
<p>Des-Glu(3)-semaglutide is a semaglutide-related impurity. This des-amino acid form has got the glutamic acid or glutamate (Glu) amino acid from position 3 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.</p>Formula:C182H284N44O56Peso molecolare:3,984.53 g/molBortezomib intermediate I
CAS:<p>Bortezomib intermediate I is a metabolite of bortezomib, which is a research and development drug product. Bortezomib intermediate I is an impurity standard for bortezomib. Bortezomib intermediate I can be synthesized from the corresponding compound. It is an analytical standard used in pharmacopoeia and can be used as an API impurity or synthetic material in drug development. Bortezomib intermediate I has a high purity, natural origin, and a niche application. CAS No. 1248339-44-7</p>Formula:C25H36BN5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:481.4 g/molSemaglutide Impurity 54 (D-Ala 18)
<p>D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/mol(R)-3-Methyl-1-(pyrazine- 2-carboxamido)butylboronic acid
<p>The compound is a drug product, analytical, and research material. The molecule has been synthesized and purified by the company's chemists. It is not an API impurity but an impurity standard for HPLC. This compound is a synthetic chemical that does not occur naturally in any living organism. It has been developed for use in drug development and research. The compound was custom synthesized by the company's chemists to meet customer demand for high purity standards of this compound. It is used as a pharmacopoeia standard for HPLC analysis and drug development.</p>Purezza:Min. 95%D-Ala(24)-Semaglutide
<p>D-Ala(24)-Semaglutide is a semaglutide impurity. The amino acid at position 24 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molSemaglutide Impurity 29 (β-Asp-9)
<p>Beta-Asp-(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the beta-aspartic acid (also known as isoaspartic, isoAsp, β-Asp or beta-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molSemaglutide Impurity 51 (D-Thr 7)
<p>D-Thr(7)-Semaglutide is a semaglutide impurity. The amino acid at position 7 has been replaced by the D-form of the amino acid D-threonine (D-Thr). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molSemaglutide Impurity 59
<p>D-Arg(28)-Semaglutide is a semaglutide impurity. The amino acid at position 28 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molLisinopril EP Impurity E
CAS:<p>Lisinopril EP Impurity E is an impurity of lisinopril, which is a prescription drug used to treat high blood pressure. This impurity was found in a preparative high performance liquid chromatography (HPLC) and mass spectroscopy analysis of the drug. The molecular weight of Lisinopril EP Impurity E was determined to be 317.2 amu, which corresponds to the molecular formula C7H13NO2. The FT-IR spectrum showed that this impurity has an ammonium group at 1859 cm-1 and butanoic acid at 1647 cm-1.</p>Formula:C21H31N3O5Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:405.49 g/molD-Ser-(12)-Semaglutide
<p>D-Ser(12)-Semaglutide is a semaglutide impurity. The amino acid at position 12 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molD-Asp(9)-Semaglutide
<p>D-Asp(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the D-form of the amino acid D-aspartic acid (D-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Formula:C187H291N45O59Peso molecolare:4,113.64 g/molLisinopril
CAS:<p>Lisinopril, an ACE inhibitor, treats hypertension, heart failure, heart attacks, and prevents diabetes-related eye and kidney issues.</p>Formula:C21H31N3O5Purezza:97.59% - 99.34%Colore e forma:SolidPeso molecolare:405.494-(Phenylamino)-1-benzyl-4-piperidinecarboxamide
CAS:Prodotto controllato<p>Applications Used as modulators of muscarinic receptors for treatment of CNS disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Coghlan, M., et al.: J. Med. Chem., 44, 1627 (2001), Ashcroft, F., et al.: J. Clin. Invest., 115, 2047 (2005), Bryan, J., et al.: Curr. Pharm. Des., 11, 2699 (2005),<br></p>Formula:C19H23N3OColore e forma:NeatPeso molecolare:309.41(S)-(-)-α-Methylbenzylamine
CAS:Prodotto controllato<p>Applications (S)-(-)-α-Methylbenzylamine (cas# 2627-86-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C8H11NColore e forma:NeatPeso molecolare:121.18(2,6-Dimethylphenoxy)acetic Acid
CAS:Prodotto controllatoFormula:C10H12O3Colore e forma:NeatPeso molecolare:180.20(1S,2S)-Bortezomib
CAS:Prodotto controllato<p>Impurity Bortezomib USP Impurity G<br>Stability Hygroscopic<br>Applications (1S,2S)-Bortezomib is an isomer of Bortezomib (B675700), proteasome inhibitor. (1S,2S)-Bortezomib has been seen to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer’s or hypertension.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hardy, J. et al.: Science, 297, 353 (2002); Paris, D. et al.: Mol. Med. 17, 149 (2011);<br></p>Formula:C19H25BN4O4Colore e forma:NeatPeso molecolare:384.24Semaglutide impurity
CAS:<p>Lipid chain (stearic bi-acid) plus γ-glutamic acid or glutamate (γ-Glu) amino acid.</p>Formula:C35H63N3O13Peso molecolare:733.89 g/molAlamethicin
CAS:<p>Alamethicin is isolated from Trichoderma viride. It is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes.</p>Formula:C92H150N22O25Purezza:98%Colore e forma:SolidPeso molecolare:1964.31CP5V
CAS:<p>CP5V, a PROTAC, degrades Cdc20, halts mitosis, and inhibits cancer growth by targeting it for VHL-mediated ubiquitination and proteasome destruction.</p>Formula:C46H66Cl3N9O12SPurezza:98%Colore e forma:SolidPeso molecolare:1075.49(2S)-1-Nitrosopyrrolidine-2-carboxamide
CAS:Prodotto controllatoFormula:C5H9N3O2Colore e forma:NeatPeso molecolare:143.14Teriparatide-d10
CAS:Prodotto controllatoFormula:C181D10H281N55O51S2Colore e forma:NeatPeso molecolare:4127.72(alphaS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride
CAS:Prodotto controllato<p>Applications (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride is a Bortezomib (B675700) intermediate which is used in the evaluation of bone-targeted proteasome inhibitors for myeloma.<br>References Agyin, J.K., et al.: Bioorg. Med. Chem. Lett., 23, 6455 (2013); Traenckner, E., et al.: EMBO. J., 13, 5433 (1994)<br></p>Formula:C24H37BN2O3·ClHColore e forma:NeatPeso molecolare:448.8341(alphaR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
CAS:Prodotto controllato<p>Applications Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.<br>References Kisselev, A., et al.: Chem. Biol., 8, 739 (2001), Kisselev, A., et al.: J. Biol. Chem., 278, 35869 (2003), Verdoes, M., et al.: Chem. Biol., 13, 1217 (2006),<br></p>Formula:C15H28BNO2·C2HF3O2Colore e forma:NeatPeso molecolare:379.22
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