Monosaccaridi

D-Mannono-1,5-lactone is a custom synthesis. It is fluorinated to give 1,5-difluoro-D-mannono-1,4,6-lactone. The methylation of the C2 hydroxyl group and the C3 keto group gives 1,5-difluoro-D-mannono-1,4,6-(methylenedioxy)lactone. Click modification of this product with azide or acetylene gives 1,5-[(azido)-(acetylenyl)] D-mannono lactone or 1,5-[(acetylene)-(azido)] D manno lactone respectively. Monosaccharides can be synthesized from these products by glycosylation with a sugar donor. Polysaccharides can be synthesized from these products by glycosylation with a sugar donor and subsequent glycosidic linkage via an olig

D-Galacturonic acid benzyl ester is a donor of d-galacturonic acid that is used to regulate the growth of bacterial cells. It has been shown to be an acceptor for oligosaccharides, which are substrates for glycosidases. D-Galacturonic acid benzyl ester has been shown to have anti-inflammatory effects in animal models and may be useful in the treatment of heart diseases, such as cardiac hypertrophy.

Propranolol D-glucuronide D6 is a synthetic, fluorinated, saccharide that is a modification of propranolol. It has high purity and can be custom synthesized to meet specific requirements. Propranolol D-glucuronide D6 has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. It is used in veterinary medicine to treat respiratory infections caused by Clostridium perfringens and other bacteria. The drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.

The reduced form of nicotinamide riboside or NRH is a potent NAD+ precursor that helps to replenish its levels in the cell. The reduced nicotinamide riboside form has shown high tolerance against degradation in plasma, which is why it is beneficial as a metabolite for the synthesis of NAD/NADH.

5-Keto-D-gluconic acid is an intermediate in the synthetic pathway of glucose. The enzyme 5-keto-D-gluconate dehydrogenase catalyzes the conversion of 5-keto-D-gluconate to D-glucono-1,5-lactone. This reaction is important for plant physiology and is used industrially for the production of citric acid. In order to synthesize 5-keto-D-gluconic acid, a p. pastoris strain was engineered with an increased expression of 5KGDH, which led to an increase in the production of this compound. This synthesis took place through a dinucleotide phosphate intermediate that was formed by two molecules of malonic acid. Citric acid was also synthesized from this intermediate.
The enzyme activity levels were measured using a bacterial strain that contained a wild type gene sequence (WT) and a mutant gene sequence (

Conduritol D (CD) is a natural product that has been isolated from the pancreas of rats. It is homochiral, and it has been shown to be active in the treatment of diabetic patients. CD has a hydroxy group at C-4' and an alcohol group at C-5'. The functional groups are acetylated at C-3', which may make this compound more potent than other similar compounds with different functional groups. It is also synthesized stereoselectively, making it a selective molecule. CD has been shown to have pharmacokinetic properties that may be beneficial for treating diabetes.

Caffeic acid 3-O-b-D-glucuronide (3BGA) is a phenolic compound that is found in plants. It has been shown to inhibit the growth of viruses, including influenza virus, and chlorogenic acid isomers have been shown to inhibit the growth of bacteria. The highest concentration of 3BGA was found in the heartwood of the plant. Recent pharmacokinetic studies have shown that caffeic acid 3-O-b-D-glucuronide is metabolized by gut bacteria and excreted in human urine.

Raloxifene-4'-D-glucuronide D4 lithium salt is a synthetic glycosylate drug, which belongs to the group of anti-estrogens. Raloxifene-4'-D-glucuronide D4 lithium salt is used for the treatment of postmenopausal osteoporosis and prevention of osteoporotic fractures in women with intact uterus. It has been shown to inhibit bone resorption, increase bone mineral density and reduce the incidence of vertebral fractures in postmenopausal women. Raloxifene-4'-D-glucuronide D4 lithium salt can be synthesized using a click chemistry reaction which involves the addition of an azide to an alkyne followed by copper catalysis and subsequent reduction with sodium borohydride. Synthesis of this compound can be achieved without any purification steps due to its high purity.

1-Deoxy-1-nitro-L-mannitol is an irreversible inhibitor of the enzyme mannitol dehydrogenase. It also inhibits other enzymes, such as L-arabinose isomerase and L-azide amidohydrolase, which are involved in the biosynthesis of arabinose and azide. The synthesis of 1-deoxy-1 nitro mannitol can be achieved through a one step reaction with hydroxide and l-arabinose (or l-xylose) in the presence of carbonate or sulfate. This product can be used in syntheses of amphoteric compounds.