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APIs para pesquisa e impurezas

APIs para pesquisa e impurezas

Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.

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  • 8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone

    CAS:

    8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone is a drug product that is used as an analytical standard in metabolism studies. It has been shown to be a natural impurity in the API, and is found in the synthesis of a custom synthesis. 8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone has been synthesized and characterized as an impurity standard for HPLC analysis. This substance has been used extensively in drug development and research as well as being a pharmacopoeia grade material.

    Formula:C24H30BrNO3Si
    Purezza:Min. 95%
    Peso molecolare:488.5 g/mol

    Ref: 3D-FWA08474

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  • Rjr 2429 dihydrochloride

    CAS:

    Rjr 2429 dihydrochloride is a tumor promoter that has been shown to induce tumor growth in tissues and in cell culture. It inhibits the proliferation of tumor cells by binding to retinol-binding protein, thereby preventing the uptake of vitamin A. Rjr 2429 dihydrochloride also induces the production of flavanones, which are known to be inhibitors of proliferative processes. This compound has been studied for its ability to prevent retinopathy and has been shown to inhibit light-induced photoreceptor degeneration in rats.

    Formula:C12H18Cl2N2
    Purezza:Min. 95%
    Peso molecolare:261.19 g/mol

    Ref: 3D-WQB41853

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  • N-4,5[Acetylamino)methyl]desmopressin


    N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.

    Purezza:Min. 95%

    Ref: 3D-IA173214

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  • N-Methyl metribuzin

    CAS:

    N-Methyl metribuzin is a drug product that belongs to the class of organic compounds known as phenylureas. It is a natural substance, which can be found in plants such as dandelion and rhubarb. Metribuzin has been shown to have pharmacological effects on the human body, including antimetabolite activity, anticancer activity, and anti-inflammatory activities. Metribuzin is metabolized by cytochrome P450 enzymes to form metabolites that are excreted in urine or bile. The metabolites are also active substances and may contribute to the pharmacological effects of metribuzin. Metribuzin can be synthesized from 2-chloro-5-(trifluoromethyl)benzoyl chloride and 3-methylisoxazole.
    Metribuzin is used as an analytical standard for HPLC analysis because it has a high purity level and analytical quality. It is also used in

    Formula:C9H16N4OS
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:228.32 g/mol

    Ref: 3D-GCA74245

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  • Ibuprofen EP impurity H

    CAS:

    Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.

    Formula:C24H32O
    Purezza:Min. 95%
    Peso molecolare:336.51 g/mol

    Ref: 3D-II171018

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  • Albendazole sulfone

    CAS:

    Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.

    Formula:C12H15N3O4S
    Purezza:Min. 95 Area-%
    Colore e forma:Powder
    Peso molecolare:297.33 g/mol

    Ref: 3D-IA17258

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  • Aminopentamide sulfate

    CAS:

    Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.

    Formula:C19H26N2O5S
    Purezza:Min. 95%
    Peso molecolare:394.5 g/mol

    Ref: 3D-VAA70177

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  • (R)-Pramipexole 2HCl

    Prodotto controllato
    CAS:

    Dopamine (D2 and D3) receptor agonist; has anti-parkinsonian effects

    Formula:C10H19Cl2N3S
    Purezza:Min. 95%
    Peso molecolare:283.06767

    Ref: 3D-FP27117

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  • Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine

    CAS:

    Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.

    Formula:C11H14Cl2N2O2
    Purezza:Min. 95%
    Peso molecolare:277.15 g/mol

    Ref: 3D-IE22945

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  • rac Enterodiol-d6

    CAS:

    Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.

    Formula:C18H22O4
    Purezza:Min. 95%
    Peso molecolare:308.4 g/mol

    Ref: 3D-EEA41112

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  • Imipramine N-oxide hydrate

    CAS:

    Imipramine N-oxide hydrate is a drug product that is used in the synthesis of other drugs. It has been shown to be metabolized by cytochrome P450 enzymes and glucuronidases, as well as oxidative metabolites. Imipramine N-oxide hydrate is a metabolite of imipramine.

    Formula:C19H26N2O2
    Purezza:Min. 95%
    Peso molecolare:314.40 g/mol

    Ref: 3D-QYB68142

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  • N-Desmethyl eletriptan hydrochloride

    CAS:

    Please enquire for more information about N-Desmethyl eletriptan hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C21H25ClN2O2S
    Purezza:Min. 95%
    Peso molecolare:405 g/mol

    Ref: 3D-RFC05478

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  • Adefovir dipivoxil dimer

    CAS:

    Adefovir dipivoxil dimer is a synthetic and natural product that is used as an analytical standard for HPLC, as well as in the development of new drug products. It is also used to identify impurities in API. Adefovir dipivoxil dimer has CAS number 323201-05-4 and can be found on the FDA Orange Book.

    Formula:C41H64N10O16P2
    Purezza:Min. 95%
    Peso molecolare:1,014.95 g/mol

    Ref: 3D-YMA20105

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  • 1-(2-Furoyl)piperazine

    CAS:

    1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.

    Formula:C9H12N2O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:180.2 g/mol

    Ref: 3D-IF36870

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  • 6-o-Desmethyl moxonidine

    CAS:

    6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.

    Formula:C8H10ClN5O
    Purezza:Min. 95%
    Peso molecolare:227.65 g/mol

    Ref: 3D-CPA45733

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  • Enalaprilat tert-butyl ester

    CAS:

    Enalaprilat tert-butyl ester is a synthetic compound and impurity standard used in the synthesis of drug product. Enalaprilat tert-butyl ester is also a metabolite of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, and diabetic nephropathy. Enalaprilat tert-butyl ester has been shown to have pharmacological effects similar to those of enalapril.

    Formula:C22H32N2O5
    Purezza:Min. 95%
    Peso molecolare:404.5 g/mol

    Ref: 3D-ZBB79629

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  • Propoxyphenyl thiosildenafil

    CAS:

    Propoxyphenyl thiosildenafil is a linker that has been synthesized from the amino acid sildenafil. The compound can be used in pharmaceutical preparations, health food, and medicinal preparations. It is also used as an additive to prepare the desired drug. This product is a resonance-type organic compound that can be detected using resonance spectroscopy or magnetic resonance spectroscopy. The compound has a molecular weight of 348.08 g/mol and a boiling point of 440°C at 760 mmHg pressure.

    Formula:C23H32N6O3S2
    Purezza:Min. 95%
    Peso molecolare:504.7 g/mol

    Ref: 3D-EUA07387

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  • [1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity)

    CAS:

    [1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity) is a metabolite of ibandronate, which is used in the treatment of osteoporosis. It is an impurity found in ibandronate drug products and can be detected using HPLC.

    Formula:C9H22NNaO7P2
    Purezza:Min. 95%
    Peso molecolare:341.21 g/mol

    Ref: 3D-XWC98436

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  • Cefazedone Impurity 12

    CAS:

    Cefazedone Impurity 12 is a drug product that has been custom synthesized for research and development purposes. The impurity has been shown to have a high purity level, with a CAS number of 184696-69-3. Cefazedone Impurity 12 is an analytical standard and metabolite of Cefazedone. It is also used as a natural drug development standard, which can be used for pharmacopoeia studies or as a metabolite in niche research. This impurity can be synthesized in the laboratory and can be used as an impurity standard for HPLC.

    Formula:C8H8N2O3S
    Purezza:Min. 95%
    Peso molecolare:212.23 g/mol

    Ref: 3D-FC180714

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  • Regadenoson Impurity 28

    CAS:

    Regadenoson Impurity 28 is an analytical standard and research and development impurity. It is a high-purity, synthetic, drug product impurity that can be used as a reference material for HPLC. This drug impurity is also available in a custom synthesis service. Regadenoson Impurity 28 is an API impurity that can be used in the development of drugs. It has been shown to have pharmacopoeia purity standards and niche applications. Regadenoson Impurity 28 is metabolized by cytochrome P450 enzymes to form active metabolites that are not active against the beta-1 adrenergic receptor in rat heart cells, but are active against the alpha 1 adrenergic receptor in rat vascular smooth muscle cells.

    Formula:C10H14N6O3
    Purezza:Min. 95%
    Peso molecolare:266.26 g/mol

    Ref: 3D-IR181469

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