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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

Sottocategorie di "APIs per la ricerca e le impurità"

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  • Levonorgestrel EP Impurity P

    CAS:

    Soluble in Chloroform & in Methanol Confirmed
    Insoluble in Wate

    Purezza:90% min
    Colore e forma:Off White or Beige Solid
    Peso molecolare:312.45

    Ref: ML-LNG16

    10mg
    Prezzo su richiesta
  • Chlorhexidine digluconate impurity K dihydrochloride

    CAS:
    Chlorhexidine digluconate impurity K dihydrochloride is a drug product that is an analytical standard. It is a natural metabolite of chlorhexidine digluconate, which is a synthetic compound. Chlorhexidine digluconate impurity K dihydrochloride has been shown to have anti-inflammatory properties and to inhibit the production of prostaglandins in animal studies. The pharmacopoeia designation for this drug product is USP/NF.
    Formula:C22H29Cl2N9O
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:506.43 g/mol

    Ref: 3D-FC173457

    500µg
    258,00€
    1mg
    378,00€
    2mg
    538,00€
    5mg
    829,00€
    10mg
    1.202,00€
  • N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine

    CAS:

    N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine is a metabolite of guanidine. It is a synthetic compound that is used as an analytical reference standard and impurity in pharmaceutical products. It is also used to create an impurity standard for HPLC analysis. This compound has been found in natural sources such as plants and animal tissues, but it can also be synthesized in the lab. The CAS number for this substance is 74886-59-2.

    Formula:C10H18N8S2
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:314.43 g/mol

    Ref: 3D-ID58189

    50mg
    225,00€
    100mg
    371,00€
    200mg
    564,00€
    500mg
    2.052,00€
  • 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt


    2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt is a white to off-white crystalline powder. It is soluble in water and sparingly soluble in alcohol. This product is used as an analytical standard and has been found to be a metabolite of the drug clozapine. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt has also been found to be an impurity in the drug product lamotrigine.
    Formula:C24H29NO5•Na
    Purezza:Min. 95%
    Peso molecolare:434.49 g/mol

    Ref: 3D-IB178523

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  • (RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

    CAS:
    Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6
    Formula:C18H20N2O6
    Purezza:Min. 95%
    Colore e forma:Yellow Powder
    Peso molecolare:360.36 g/mol

    Ref: 3D-IM57947

    10mg
    135,00€
    25mg
    165,00€
    50mg
    225,00€
    100mg
    338,00€
    250mg
    469,00€
  • Levonorgestrel EP Impurity O

    CAS:

    Soluble in Chloroform & in Methanol Confirmed
    Insoluble in Water

    Purezza:95.0% Min
    Colore e forma:Off White or Beige Solid
    Peso molecolare:344.49

    Ref: ML-LNG15

    10mg
    Prezzo su richiesta
  • Bis{2-[(2S-trans)-Methyl 7-chloro-6,7,8-trideoxy-6-[((1-methyl-4-propyl-2-pyrrolidinyl)-carbonyl)amino]-1-thio-L-threo-a-D-galacto-o ctopyranoside]} pyrophosphate

    CAS:
    CAS No. 37450-78-5, drug product, Custom synthesis, High purity, analytical, Metabolism studies, Natural, Drug development, pharmacopoeia, Metabolite, niche, Synthetic
    Formula:C36H66Cl2N4O15P2S2
    Purezza:Min. 95%
    Peso molecolare:991.91 g/mol

    Ref: 3D-IM58171

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  • N-[1-(R)-(+)-(2-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride

    CAS:
    N-[1-(R)-(+)-(2-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride is a metabolite that is produced by the metabolism of naphthalene. It is an impurity in the naphthalene standard, which is used as an API to assess the purity of other substances. N-[1-(R)-(+)-(2-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride has been shown to be a substrate for CYP2D6. This metabolite is also found in pharmaceuticals and other drugs.
    Formula:C22H22F3N•HCl
    Purezza:Min. 95%
    Peso molecolare:393.87 g/mol

    Ref: 3D-IN58182

    100mg
    135,00€
    250mg
    163,00€
    500mg
    336,00€
    1g
    466,00€
  • (RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate

    CAS:
    (RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate is a drug product with an analytical purpose. This compound is metabolized by the liver and excreted in the urine. It has been shown that this compound is not present in natural sources. The CAS number for this compound is 1316606-40-2 and it's API impurity is less than 0.0001%. This drug product has been synthesized from a custom synthesis and it is an impurity standard for HPLC analyses. It has also been used as a research and development tool to develop drugs or study metabolism studies. This compound is pure enough to be used as a pharmacopoeia standard
    Formula:C21H26N2O7
    Purezza:Min. 95%
    Peso molecolare:418.44 g/mol

    Ref: 3D-II57938

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  • N-Despropyl ropinirole hydrochloride

    CAS:
    N-Despropyl ropinirole hydrochloride is a synthetic drug product that is used as a research and development impurity standard. It is also used in the synthesis of other drugs and has been shown to have an analytical purity of 99%. N-Despropyl ropinirole hydrochloride is not active against bacteria, fungi, or viruses.
    Formula:C13H19ClN2O
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:254.75 g/mol

    Ref: 3D-YGA99076

    25mg
    312,00€
    50mg
    458,00€
    100mg
    651,00€
    250mg
    926,00€
    500mg
    1.163,00€
  • 2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene

    CAS:
    2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene is a synthetic compound that has been used as an impurity standard for the drug product and API. It has also been used for the pharmacopoeia, research and development, and analytical purposes. This compound is a metabolite of erythromycin.
    Formula:C18H19NOS
    Purezza:Min. 95%
    Colore e forma:White To Pink Or Yellow Solid
    Peso molecolare:297.42 g/mol

    Ref: 3D-IM58098

    50mg
    136,00€
    100mg
    198,00€
    250mg
    282,00€
    500mg
    454,00€
  • Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate

    CAS:
    Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate is a hydrophobic, colorless liquid with a pungent odor. It is an additive that can be used in the manufacturing of epoxy resins to increase their light resistance and corrosion resistance. This product also has immunity properties and may be used as an immunotherapy agent for the treatment of viral infections. Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate has been shown to activate immune cells and promote cell immunity by increasing the production of cytokines. It may also be used as a virus transfer agent for the prevention of viral infection.
    Formula:C12H16N2O4
    Purezza:Min. 95%
    Colore e forma:White to off-white powder.
    Peso molecolare:252.27 g/mol

    Ref: 3D-IM07158

    10mg
    135,00€
    25mg
    148,00€
    50mg
    198,00€
    100mg
    310,00€
    250mg
    1.005,00€
  • 2-[4-(2-Methylpropanoyl)phenyl] propanoic acid

    CAS:
    2-[4-(2-Methylpropanoyl)phenyl] propanoic acid is a pharmaceutical intermediate that is used for the production of carprofen. It has been found to be an analytical method for the determination of 4-hydroxybenzoic acid and 4-isobutylacetophenone. The compound is analyzed by chromatographic methods and electrophoresis methods. The optimization of the solvent composition, flow rate, and impurities during the synthesis process are also studied in this research. 2-[4-(2-Methylpropanoyl)phenyl] propanoic acid has been found to be a meaningful validation of analytical methods for medicines, with an impurity limit of 0.1%.
    Formula:C13H16O3
    Purezza:Min. 98 Area-%
    Colore e forma:Powder
    Peso molecolare:220.26 g/mol

    Ref: 3D-IM15852

    1mg
    244,00€
    2mg
    366,00€
    5mg
    592,00€
    10mg
    841,00€
    25mg
    1.123,00€
  • Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside

    CAS:
    Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is a synthetic impurity standard for the drug product. It has been used in studies on metabolism and as an analytical reference material. Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is also available as a custom synthesis at high purity.
    Formula:C22H24O6
    Purezza:Min. 95%
    Colore e forma:White powder.
    Peso molecolare:384.42 g/mol

    Ref: 3D-IM45444

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  • N-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)sulphinyl]-2-hydroxy-2-methylpropanamide

    CAS:
    This drug product is a custom synthesis, CAS No. 2200280-97-1, drug development, Metabolite, Synthetic, Impurity standard, Metabolism studies, API impurity, Natural (pharmacopoeia), analytical (HPLC standard), Research and Development (High purity). It is a metabolite of the drug N-[4-amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)sulphinyl]-2-hydroxy-2-methylpropanamide. This compound has been shown to have high affinity for the dopamine receptor with an IC50 of 0.5 nM.
    Formula:C18H16F4N2O5S
    Purezza:Min. 95 Area-%
    Colore e forma:White to off-white solid.
    Peso molecolare:448.39 g/mol

    Ref: 3D-IA58277

    25mg
    135,00€
    50mg
    197,00€
    100mg
    282,00€
  • N-Methyl zonisamide

    CAS:
    N-Methyl zonisamide is a drug that is an impurity in Zonisamide. It is an analog of the drug and has been used as a research and development standard for Zonisamide. N-Methyl zonisamide can be synthesized from the corresponding nitrobenzene, aminobenzene, and formaldehyde. The synthesis can be performed by converting nitrobenzene to aminobenzene with sodium hydroxide in methanol, followed by conversion to N-methyl zonisamide with formaldehyde in ethanol. Pharmacopoeia standards for this compound are available from Sigma Aldrich, which can be purchased from our website.
    Formula:C9H10N2O3S
    Purezza:Min. 95 Area-%
    Colore e forma:Powder
    Peso molecolare:226.25 g/mol

    Ref: 3D-IM25576

    10mg
    338,00€
    25mg
    513,00€
    50mg
    885,00€
    100mg
    1.515,00€
    250mg
    2.684,00€
  • 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

    CAS:

    6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is a metabolite that can be found in the urine and blood of humans. It has been shown to have cytotoxic effects on human lymphocytes and erythrocytes. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is used as an impurity standard for HPLC analysis and as a reference compound for pharmacopoeia. This chemical is also used in the synthesis of some drugs. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is not listed in any pharmacopoeia or natural product database.

    Formula:C9H7Cl2N5
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:256.09 g/mol

    Ref: 3D-ID20869

    25mg
    135,00€
    50mg
    165,00€
    100mg
    225,00€
    250mg
    369,00€
  • Semaglutide Impurity 56 (D-Glu 21)


    D-Glu(21)-Semaglutide is a semaglutide impurity. The amino acid at position 21 has been replaced by the D-form of the amino acid D-glutamic acid (D-Glu). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.
    Formula:C187H291N45O59
    Peso molecolare:4,113.64 g/mol

    Ref: 3D-IS27843

    1mg
    471,00€
    10mg
    2.340,00€
    100mg
    7.020,00€
  • 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

    CAS:

    3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one is an impurity in the drug development process. It is used as a standard for HPLC testing and a synthetic intermediate. It has been shown to have niche use in the pharmaceutical industry. 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one has been found to be metabolized through oxidation and reduction reactions, leading to the formation of metabolites such as 2,6-dihydroxypyridine (DHP). Further metabolism studies are required for this substance.

    Formula:C14H18N2O4
    Purezza:Min. 95%
    Colore e forma:White to off-white solid.
    Peso molecolare:278.3 g/mol

    Ref: 3D-IM58041

    5mg
    141,00€
    10mg
    170,00€
    25mg
    230,00€
    50mg
    570,00€
    100mg
    896,00€
  • Cetirizine glycerol ester impurity

    CAS:
    Cetirizine glycerol ester impurity is a drug product that is an analytical impurity. It is a natural, API impurity, and synthetic. The CAS number for this impurity is 1243652-36-9. Research and Development (R&D) of cetirizine glycerol ester impurity is required for the manufacture of pharmaceutical products. High purity cetirizine glycerol ester impurity can be used as a pharmacopoeia standard for HPLC analyses.
    Formula:C24H31ClN2O5
    Purezza:Min. 95%
    Peso molecolare:462.97 g/mol

    Ref: 3D-IC57782

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