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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • Fluocortolone Impurity 4

    CAS:

    Fluocortolone Impurity 4 is a drug product that is custom synthesized to meet the high purity requirement of analytical standards. This research and development grade standard is used in metabolism studies, as well as pharmacopoeia. Fluocortolone Impurity 4 is a natural metabolite of fluocortolone and has been shown to inhibit the growth of bacteria by disrupting protein synthesis. It can be found in the urine, feces, and plasma of humans. Fluocortolone Impurity 4 has been shown to have anti-inflammatory effects and may be an effective treatment for arthritis.

    Purezza:Min. 95%

    Ref: 3D-IF180664

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  • 3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxy-thymidine

    CAS:

    3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxythymidine is an analytical standard used in the R&D and drug development of 3'-azido derivatives of thymidine. It is a synthetic intermediate that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV) replication and to inhibit intracellular HIV type 2 (HIV2) production in cultured cells. 3'-[3-(3-Azido-2,3,-dideoxy--b erythro--pentofuranosyl)-3,6--dihydro--5--methyl--2,6--dioxo--1(2H)--pyrimidinyl]-

    Formula:C20H25N7O8
    Purezza:95%Nmr
    Peso molecolare:491.45 g/mol

    Ref: 3D-IA145570

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  • 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan

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    CAS:
    4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-
    Formula:C22H22N2O6
    Purezza:Min. 95%
    Peso molecolare:410.4 g/mol

    Ref: 3D-JGA30803

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  • 6-o-Desmethyl moxonidine

    CAS:

    6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.

    Formula:C8H10ClN5O
    Purezza:Min. 95%
    Peso molecolare:227.65 g/mol

    Ref: 3D-CPA45733

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  • 4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-pyridinium Chloride Monoh ydrochloride

    CAS:

    4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium Chloride Monohydrochloride is a drug product under development for the treatment of bacterial infections. 4-[2-[(6R,7R)-7Amino--2carboxy8oxo5thia1azabicyclo[4.2.0]oct2en3yl]thio]-4thiazolyl]-1methylpyridinium Chloride Monohydrochloride is an impurity in the API Methicillin (CAS No. 40082764). Impurities are not necessarily undesirable and may have substantial therapeutic value or provide a desired

    Formula:C16H15N4O3S3·Cl·HCl
    Purezza:Min. 95%
    Peso molecolare:479.43 g/mol

    Ref: 3D-IA172859

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  • rac-Norphenylephrine hydrochloride

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    CAS:

    Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).

    Formula:C8H12ClNO2
    Purezza:Min. 95%
    Peso molecolare:189.64 g/mol

    Ref: 3D-IN27563

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  • Tetracosanoic-d47 acid

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    CAS:

    Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.

    Formula:C24HD47O2
    Purezza:Min. 95%
    Peso molecolare:415.93 g/mol

    Ref: 3D-TCA06000

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  • Tolterodine S-enantiomer

    CAS:

    Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.

    Formula:C22H31NO·C4H6O6
    Purezza:Min. 95%
    Peso molecolare:475.57 g/mol

    Ref: 3D-YJB55103

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  • Ceftazidime impurity H

    CAS:

    Ceftazidime impurity H is a by-product that can be found in the synthesis of ceftazidime. It has been detected using magnetic separation and UV detection. Ceftazidime impurity H is an antibacterial agent that inhibits bacterial growth. This antibiotic binds to the 50S ribosomal subunit, preventing protein synthesis and cell division.

    Formula:C23H24N6O7S2
    Purezza:Min. 95%
    Peso molecolare:560.6 g/mol

    Ref: 3D-IC63721

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  • Deschloro-zopiclone

    CAS:

    Deschloro-zopiclone is a drug product that is custom synthesized for research and development purposes. It is a synthetic drug that has been shown to have pharmacological properties in the treatment of insomnia. Deschloro-zopiclone is metabolized by hydrolysis, oxidation and conjugation, with the major metabolites being 2,5-dimethoxybenzoic acid and 2-hydroxy-5-methoxybenzoic acid. The metabolite 2,5-dimethoxybenzoic acid has been shown to be responsible for the hypnotic effects of deschloro-zopiclone.

    Formula:C17H18N6O3
    Purezza:Min. 95%
    Peso molecolare:354.4 g/mol

    Ref: 3D-YDC04661

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  • Rocuronium EP Impurity G

    CAS:

    Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.

    Formula:C27H46N2O3
    Purezza:Min. 95%
    Peso molecolare:446.67 g/mol

    Ref: 3D-IR178406

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  • Abt-639 hydrochloride

    CAS:

    Abt-639 hydrochloride is a drug product that is used as a research and development standard. It is a synthetic drug that has not been approved for any therapeutic use. Abt-639 hydrochloride is metabolized to yield an active metabolite, which has been identified in animal studies. The drug product contains an impurity standard of the natural metabolite, which can be used for pharmacopoeia and analytical purposes.

    Formula:C20H21Cl2F2N3O3S
    Purezza:Min. 95%
    Peso molecolare:492.4 g/mol

    Ref: 3D-KZB56031

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  • Ajoene

    CAS:

    Ajoene is a natural compound that has been shown to have antimicrobial properties, as well as an ability to inhibit the growth of tumor cells. Ajoene is also a potent inhibitor of dextran sulfate proteoglycan synthesis in vitro and has been shown to produce a hypoglycemic effect in vivo. Ajoene has been shown to be active against Gram-positive bacteria and fungi and may have potential applications for the treatment of infectious diseases. Further research is needed to determine whether ajoene may be used as an antioxidant or neuroprotective agent.

    Formula:C9H14OS3
    Purezza:Min. 95%
    Peso molecolare:234.4 g/mol

    Ref: 3D-SDA28499

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  • Benz[A]anthracene-7-chloromethane-13C

    CAS:

    Please enquire for more information about Benz[A]anthracene-7-chloromethane-13C including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C19H13Cl
    Purezza:Min. 95%
    Peso molecolare:277.7 g/mol

    Ref: 3D-RFC05460

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  • 7-O-methyl ivermectin B1a


    7-O-methyl ivermectin is a drug product that is an analytical standard for the impurity 7-O-methyl ivermectin B1a. Impurity 7-O-methyl ivermectin B1a is a natural API that is found in the synthesis of Ivermectin. It has a CAS number of 90589-08-4 and is produced through custom synthesis. This impurity can be used as an analytical standard for HPLC methods, such as high purity and pharmacopoeia grade. 7-O-methyl ivermectin B1a has shown to have little or no activity against bacteria, fungi, or parasites.

    Purezza:Min. 95%

    Ref: 3D-IO167868

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  • N-Formyl Saxagliptin


    N-Formyl Saxagliptin is an analytical standard for HPLC. It is used as a drug development and API impurity in the pharmaceutical industry. It was synthesized by reacting formaldehyde with the amino acid L-glutamic acid, followed by purification to remove any other contaminants. The CAS number for this chemical is 57847-82-0.

    Purezza:Min. 95%

    Ref: 3D-IF162360

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  • Carbidopa 4-phosphate trihydrate

    CAS:

    Please enquire for more information about Carbidopa 4-phosphate trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C10H21N2O10P
    Purezza:Min. 95%
    Peso molecolare:360.25 g/mol

    Ref: 3D-HBD68607

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  • CPI 0610

    CAS:

    CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.

    Formula:C20H18ClN3O3
    Purezza:Min. 95%
    Peso molecolare:383.8 g/mol

    Ref: 3D-VYC72614

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  • Epi-canagliflozin

    CAS:

    Epi-canagliflozin is a drug product that is manufactured by HPLC. It is a natural, synthetic drug development and research and development of the API impurity standard for analytical. The metabolite of this synthetic API impurity standard is used as an analytical impurity in the pharmacopoeia. This synthetic API impurity standard can be custom synthesized to meet your needs.

    Formula:C24H25FO5S
    Purezza:Min. 95%
    Peso molecolare:444.5 g/mol

    Ref: 3D-PNC59087

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  • Genistein 4’-β-D-glucuronide

    CAS:

    Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.

    Formula:C21H18O11
    Purezza:Min. 95%
    Peso molecolare:446.4 g/mol

    Ref: 3D-VJA08407

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