Product Information
- Pyr-His-Pro-.beta.NA
- 5-oxo-L-prolyl-3-(4H-imidazol-4-yl)-N-{[(2S)-1-(naphthalen-2-yl)pyrrolidin-2-yl]carbonyl}-L-alaninamide
A sensitive and highly specific substrate for a rapid assay of rat brain TRH-deamidating enzyme (prolyl endopeptidase). TRH-bNA is also hydrolyzed by another TRH-degrading enzyme, pyroglutamyl peptidase II (thyroliberinase), which seems to play a key role in terminating the biological activity of neuronally released TRH.
Chemical properties
Technical inquiry about: 01-4004755 TRH-βNA
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