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Amyloid β-Protein (1-42)
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Amyloid β-Protein (1-42)

CAS: 107761-42-2

Ref. 01-4014447

1mg
467.00 €Add to cart
5mg
1,622.00 €Add to cart
10mg
2,757.00 €Add to cart
25mg
6,605.00 €Add to cart
0.1mg
100.00 €Add to cart
0.5mg
320.00 €Add to cart
Estimated delivery in United States, on Friday 26 Aug 2022

Product Information

Name:
Amyloid β-Protein (1-42)
Synonyms:
  • Aβ42, β-Amyloid (1-42)
  • Beta-Amyloid Peptide (1-42), Human
  • Daefrhdsgyevhhqklvffaedvgsnkgaiiglmvggvvia
  • Amyloid Beta-Peptide (1-42) (Human)
  • Amyloid B-Protein Fragment 1-42
  • Amyloidb-Peptide(1-42)(human)
  • H-Asp-Ala-Glu-Phe-Arg-His-Asp--Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-OH
  • H-asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Gly-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Ile-Ala-OH
  • Abeta 1-42
  • β-Amyloid(1-42)Human
  • See more synonyms
Description:

Ab 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Ab 1-42 readily forms neurotoxic oligomers at physiological pH. On the other hand, the peptide shows antimicrobial activity. The sequence of this peptide corresponds to the sequence of human, bovine, canine, feline, ovine, guinea pig, and rabbit Ab42. The peptide has been used to detect amyloid b-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients through fluorescence correlation spectroscopy. For detailed descriptions of the preparation of Ab 1-42 monomers and protofibrils please see the papers of Jan, Hartley, and Lashuel, Stine et al. (2011), and of Broersen and colleagues. The findings of Ryan et al. indicate that 10% ammonia disaggregates Ab42 more efficiently than HFIP.

Long term storage:
Notes:

Chemical properties

Molecular weight:
4514.1
Formula:
C203H311N55O60S
Purity:
98.1%
Color/Form:
White Lyophilisate
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
GHS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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