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Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide
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Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide

CAS: 143120-27-8

Ref. 01-4020214

1mg
245.00 €
5mg
936.00 €
Estimated delivery in United States, on Monday 13 May 2024

Product Information

Name:
Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide
Synonyms:
  • G 4120
  • Cyclo(S-acetyl-tyrosyl-arginyl-glycyl-aspartyl-cysteinyl-OH) (sulfoxide)
  • Cyclo-S-Ac-tyr-arg-gly-asp-cys-OH (sulfoxide)
  • Cyclo-S-Ac-tyr-rgd-cys-OH (sulfoxide)
  • L-Cysteine, N-(mercaptoacetyl)-D-tyrosyl-L-arginylglycyl-L-alpha-aspartyl-, cyclic (1-5)-disulfide, S-oxide
  • (3R,6S,12S,15R)-6-(carboxymethyl)-12-{3-[(diaminomethylidene)amino]propyl}-15-(4-hydroxybenzyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacyclooctadecane-3-carboxylic acid 1-oxide
Description:

This sulfur-bridged cyclic RGD peptide is a potent inhibitor of the binding of glycoprotein IIb/IIIa to fibrinogen with an IC50 of 1.5 nM. Furthermore, it is a highly potent inhibitor of fibrinogen-mediated platelet aggregation (IC50 = 0.15 uM). Its antithrombotic activity in vivo may render this compound useful in the treatment of arterial thromboembolic diseases.

Brand:
Bachem
Long term storage:
Notes:

Chemical properties

Molecular weight:
668.69
Formula:
C26H36N8O11S
Color/Form:
White
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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