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Product Information
Name:
H-Cys-psi(CH₂NH)Val-psi(CH₂NH)Phe-Met-OH
Synonyms:
- B581
- <span class="text-smallcaps">L</smallcap>-Methionine, N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-<smallcap>L</span>-phenylalanyl-
- <span class="text-smallcaps">L</smallcap>-Methionine, N-[N-[2-[(2-amino-3-mercaptopropyl)amino]-3-methylbutyl]-<smallcap>L</span>-phenylalanyl]-, [S-(R*,S*)]-
- B 581
- Cys-((R))-Val-((R))-Phe-Met
- Ftase Inhibitor I
- H-Cys-(R)-Val-(R)-Phe-Met-Oh
- N-[(2S)-2-[[(2R)-2-Amino-3-mercaptopropyl]amino]-3-methylbutyl]-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-methionine
- N-[(2S)-2-{[(2R)-2-amino-3-sulfanylpropyl]amino}-3-methylbutyl]-L-phenylalanyl-L-methionine
- N-[(S)-2-((R)-2-Amino-3-Mercapto-Propylamino)-3-Methyl-Butyl]-Phe-Met-Oh
- See more synonyms
- N-[2(S)-(2(R)-2-Amino-3-Mercaptopropylamino)-3-Methylbutyl]-L-Phenylalanyl-L-Methionine
- N-[2(S)-[2(R)-Amino-3-Mercaptopropylamino]-3-Methyl-Butyl]-Phe-Met
- N-[2(S)-[2(R)-Amino-3-Mercaptopropylamino]-3-Methylbutyl]-Phe-Met-Oh
CAS:
Description:
B581, Cys-psi(CH2NH)-Val- psi[CH2NH]-Phe-Met is a farnesyltransferase (FTase) inhibitor of special stability and membrane permeability. Due to its high selectivity, B581 is more than 30-fold more active against FTase (IC50 = 21 nM in vitro) than against geranylgeranyltransferase (GGTase). Inhibitors of the farnesyltransferase are potential candidates for the development of anticancer drugs.
Brand:
Bachem
Long term storage:
Notes:
Chemical properties
Molecular weight:
470.7
Formula:
C22H38N4O3S2
Purity:
95.7%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 01-4025336 H-Cys-psi(CH₂NH)Val-psi(CH₂NH)Phe-Met-OH
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