Diphenyldiazomethane resin (200-400 mesh, 0.7-1.3 mmol/g)
Ref. 01-4027172
| 1g | 228.00 € | ||
| 5g | 863.00 € |
Product Information
- Ph-CN₂-Ph-polymer
Diphenyldiazomethane was used industrially for producing benzhydryl esters (diphenylmethyl esters) of b-lactam antibiotics. This "polymeric diphenyldiazomethane" readily reacts with carboxylic acids, e.g. Fmoc-amino acids, which need not to be activated. Products can be cleaved from this very acid-sensitive resin derivative with 1-5 % TFA in dichloromethane. Fmoc-a-amino alcohols can be anchored to PDDM in the presence of BF3 etherate. As the resulting benzhydryl ethers can be cleaved with 1% TFA/DCM, fully protected peptide alcohols can be obtained.
Chemical properties
Technical inquiry about: 01-4027172 Diphenyldiazomethane resin (200-400 mesh, 0.7-1.3 mmol/g)
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
