Product Information
- Ac-WEHD-AMC
- Acetyl-L-Tryptophyl-L-Glutamyl-L-Histidyl-L-Aspartic Acid Alpha-(4-Methylcoumaryl-7-Amide)
- Ac-Wehd-Mca
- Ac-Trp-Glu-His-Asp-7-Amino-4-Methylcoumarin
- Ac-Trp-Glu-His-Asp-Amc
- Ac-Trp-Glu-His-Asp-Mca
- Caspase 1 (Ice) Substrate 3M, Fluorogenic
- Caspase-1 Substrate (Fluorogenic)
With a kcat/Km of 3.3 · 10⁶ M⁻¹s⁻¹ the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently thanAc-YVAD-AMC. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
Chemical properties
Technical inquiry about: 01-4027662 Ac-Trp-Glu-His-Asp-AMC
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