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Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl)
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Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl)

CAS: 153381-95-4

Ref. 01-4029366

1mg
224.00 €Add to cart
5mg
831.00 €Add to cart
Estimated delivery in United States, on Wednesday 17 Aug 2022

Product Information

Name:
Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl)
Synonyms:
  • XJ735
  • Cyclo(-Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) Tfa
  • Cyclo(-Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) Trifluoroacetate Salt
  • Xj735 Trifluoroacetate Salt
  • Cyclo(Ala-Arg-Gly-Asp-3-Aminomethyl-*Benzoyl)Triflu
  • Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)
Description:

The small molecule RGD peptidomimetic avb3 integrin antagonist XJ-735 contains both anionic and cationic binding sites that straddle the RGD binding domain of the avb3 integrin. The IC50 values of XJ 735 for avb3-mediated inhibition of human and porcine cell adhesion, and vascular smooth muscle cell migration, ranged from 0.6 to 4.4 uM. In contrast, IC50 for porcine or human aIIb/b3, a4b1, avb5, and a5b1 inhibition exceeded 100 uM.

Long term storage:
Notes:

Chemical properties

Molecular weight:
532.56
Formula:
C23H32N8O7
Purity:
97.2%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
GHS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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