DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS
CAS: 127134-13-8
Ref. 01-4030716
| 1mg | 375.00 € | ||
| 5mg | 1,421.00 € |
Product Information
- 4-(4-Dimethylaminophenylazo)Benzoyl-Gamma-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-5-[(2-Aminoethyl)Amino]-Naphthalene-1-Sulfonic Acid
- Hiv Protease Fret Substrate I
- Dabcyl-Gaba-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Edans
- DABCYL-GAMMA-ABU-SER-GLN-ASN-TYR-PRO-ILE-VAL-GLN-EDANS
- DABCYL-γ-Abu-SQNYPIVQ-EDANS
- DABCYL-gamma-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS trifluoroacetate salt
- L-Glutamamide,N-[4-[[4-[[4-(dimethylamino)phenyl]azo]benzoyl]amino]-1-oxobutyl]-L-seryl-L-glutaminyl-L-asparaginyl-L-tyrosyl-L-prolyl-L-isoleucyl-L-valyl-N1-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-
- DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS trifluoroacetate salt
- DABCYL-g-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS
The fluorogenic HIV-1 protease substrate DABCYL-Gaba-SQNYPIVQ-EDANS consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH₂-termini. The γ-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm.
Chemical properties
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