PACAP-38 (human, mouse, ovine, porcine, rat)
CAS: 124123-15-5
Ref. 01-4031157
| 1mg | 664.00 € | ||
| 0.2mg | 172.00 € | ||
| 0.5mg | 375.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Product Information
Name:
PACAP-38 (human, mouse, ovine, porcine, rat)
Synonyms:
- Pituitary Adenylate Cyclase Activating Polypeptide-38 (human, mouse, ovine, porcine, rat)
- H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Description:
Kojro et al. observed that the PAC1 agonists PACAP-27 (H-1172) and PACAP-38 strongly increased the activity of α-secretase. Upregulation of this APP-degrading enzyme promotes the non-amyloidogenic processing of APP, i.e. reduces the production of Aβ40/42, and thus may help to prevent Alzheimer’s disease. Nasally applied PACAP-38 in APP[V717I]-transgenic mice additionally enhanced the production of the Aβ-degrading enzyme neprilysin via induction of somatostatin.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Bachem
Long term storage:
Notes:
Chemical properties
Molecular weight:
4534.32
Formula:
C203H331N63O53S
Purity:
97.6%
Color/Form:
White
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: 01-4031157 PACAP-38 (human, mouse, ovine, porcine, rat)
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