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PACAP-38 (human, mouse, ovine, porcine, rat)
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PACAP-38 (human, mouse, ovine, porcine, rat)

CAS: 124123-15-5

Ref. 01-4031157

1mg
664.00 €
0.2mg
172.00 €
0.5mg
375.00 €
Estimated delivery in United States, on Tuesday 19 Nov 2024

Product Information

Name:
PACAP-38 (human, mouse, ovine, porcine, rat)
Synonyms:
  • Pituitary Adenylate Cyclase Activating Polypeptide-38 (human, mouse, ovine, porcine, rat)
  • H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Description:

Kojro et al. observed that the PAC1 agonists PACAP-27 (H-1172) and PACAP-38 strongly increased the activity of α-secretase. Upregulation of this APP-degrading enzyme promotes the non-amyloidogenic processing of APP, i.e. reduces the production of Aβ40/42, and thus may help to prevent Alzheimer’s disease. Nasally applied PACAP-38 in APP[V717I]-transgenic mice additionally enhanced the production of the Aβ-degrading enzyme neprilysin via induction of somatostatin.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Bachem
Long term storage:
Notes:

Chemical properties

Molecular weight:
4534.32
Formula:
C203H331N63O53S
Purity:
97.6%
Color/Form:
White
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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