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BIBP3226
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BIBP3226

CAS: 159013-54-4

Ref. 01-4034548

1mg
163.00 €
Estimated delivery in United States, on Monday 10 Jun 2024

Product Information

Name:
BIBP3226
Synonyms:
  • BIBP 3226
  • (2R)-5-(Diaminomethylideneamino)-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide
  • Benzeneacetamide,N-[4-[(aminoiminomethyl)amino]-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl]-a-phenyl-, (R)-
  • Bibp 3226
  • N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide
Description:

The Y1 receptor antagonist BIBP-3226, a derivative of D-arginine, binds to the Y1 receptor with high affinity (its Ki was 7 nM versus the Ki of 0.2 nM for NPY). BIBP3226 also reduced the NPY-induced increase in intracellular calcium as well as the pressor response in vitro and in vivo. BIBP3226 inhibited NPY induced feeding in rats. In dogs, intra-arterial infusion of BIBP-3226 interrupted tonic NPY Y1 receptor-mediated vasoconstriction in exercising skeletal muscle, resulting in substantial increases in experimental limb blood flow. CAS-Number (trifluoroacetate): 1068148-47-9.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Bachem
Long term storage:
Notes:

Chemical properties

Molecular weight:
473.58
Formula:
C27H31N5O3
Purity:
98.8%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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