(D-Phe⁵,Cys⁶·¹¹,N-Me-D-Trp⁸)-Somatostatin-14 (5-12) amide
CAS: 340821-13-8
Ref. 01-4039201
1mg | 474.00 € |
Product Information
- (N-Me-D-Trp⁴,Thr⁸)-Octreotide amide
- (D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) Amide
- H-D-Phe-Cys-Phe-N-Me-D-Trp-Lys-Thr-Cys-Thr-Nh2
- H-D-Phe-Cys-Phe-N-Me-D-Trp-Lys-Thr-Cys-Thr-NH2 , (Disulfide bond)
This synthetic somatostatin analog is selective for the human somatostatin receptor subtype 5 (hsst5) with a binding affinity similar to somatostatin-28. Its Kd +/-SEM values for hsst1, hsst2, hsst3, hsst4, and hsst5 are 1200 nM, 23.5 +/- 3.92 nM, 11.05 +/- 1.03 nM, >1000 nM, and 0.61 +/- 0.36 nM, respectively. Due to its selectivity it might prove to be useful for evaluating hsst5-mediated responses.
Chemical properties
Technical inquiry about: 01-4039201 (D-Phe⁵,Cys⁶·¹¹,N-Me-D-Trp⁸)-Somatostatin-14 (5-12) amide
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