(Gln²²)-Amyloid β-Protein (1-40)
- Amyloid β-Protein (1-40) E22Q, Amyloid β-Protein (1-40) Dutch Mutation, [Gln22] β-Amyloid (1-40)
The Dutch mutation (E22Q) of amyloid b-peptide aggregates more readily than the wild-type peptide and the resulting fibrils show increased neurotoxicity. The mutant peptide E22Q induced apoptosis of cerebral endothelial cells at a concentration of 25 μm, whereas WT Ab 1-40 and the Italian mutant E22K showed no effect.
Technical inquiry about: 01-4039928 (Gln²²)-Amyloid β-Protein (1-40)
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