Endothelin-1 (human, bovine, dog, mouse, porcine, rat)

CAS: 117399-94-7

Ref. 01-4040254

Product Information

• Name: Endothelin-1 (human, bovine, dog, mouse, porcine, rat)
• Synonyms: ET-1 (human, bovine, dog, mouse, porcine, rat)
• Brand: Bachem
• Description: Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.

Chemical properties

• Molecular weight: 2491.94
• Formula: C₁₀₉H₁₅₉N₂₅O₃₂S₅
• Purity: 91.90%
• Color/Form: White