Tyr-(D-Dab⁴,Arg⁵,D-Trp⁸)-cyclo-Somatostatin-14 (4-11)
CAS: 496849-46-8
Ref. 01-4041674
| 1mg | 321.00 € | ||
| 5mg | 1,231.00 € |
Product Information
- KE 108
High affinity ligand for all five somatostatin receptors (sst1-sst5). In AtT-20 mouse anterior pituitary tumor cells which mainly express sst2 and sst5 receptors the binding affinity of this somatostatin analog was found to be higher than that of somatostatin-14 and octreotide. In a model of epileptogenesis, however, KE 108 did not exhibit antiepileptic activity suggesting that the high potency and efficacy of a synthetic ligand to all known somatostatin receptors may not reproduce entirely the effects of the natural ligand.
Chemical properties
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